Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

Autor: Laurence Amar, Jose Felipe Golib Dzib, Celso E. Gomez-Sanchez, Norbert B. Ghyselinck, I. Giscos-Douriez, Benoit Samson-Couterie, Sheerazed Boulkroun, Amanda J. Rickard, Maria-Christina Zennaro, Audrey H. Soria, Fabio L. Fernandes-Rosa, Arndt Benecke, Rami M El Zein, Marko Poglitsch, A. Rocha

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-50988-2⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)

International audience; Primary aldosteronism (PA) is the most frequent form of secondary arterial hypertension. Mutations in different genes increase aldosterone production in PA, but additional mechanisms may contribute to increased cell proliferat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cac84892b5de2a4d32234d8a6303d8c
https://hal.archives-ouvertes.fr/hal-02324112

The naturally occurring steroid solasodine induces neurogenesis in vitro and in vivo

Autor: Gábor Szabó, A.I. Hashim, I. Giscos-Douriez, Wenguo Yao, I. Dinca, Laurent Lecanu, Ferenc Erdélyi, Janet Greeson, Stefano Vicini, Vassilios Papadopoulos, Althea McCourty

Publikováno v: Neuroscience. 183:251-264

In this study, we explored the capacity of the naturally occurring compound solasodine to promote neurogenesis in vitro and in vivo. Mouse embryonic teratocarcinoma P19 cells exposed to solasodine for 2 days followed by a 5-day washout differentiated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d258f21e230417ac429c1122116e1a1f
https://doi.org/10.1016/j.neuroscience.2011.03.042

CO-33: Different somatic mutations in multinodular adrenals with aldosterone-producing adenoma

Autor: Sheerazed Boulkroun, Laurence Amar, Tchao Meatchi, Celso E. Gomez-Sanchez, Fabio L. Fernandes-Rosa, Maria-Christina Zennaro, I. Giscos-Douriez

Publikováno v: Annales de Cardiologie et d'Angéiologie. 64:S16

Background Primary aldosteronism is the most common form of secondary hypertension. Somatic mutations in KCNJ5, ATP1A1, ATP2B3 and CACNA1D are found in aldosterone producing adenoma. Additionally, adrenals with aldosterone producing adenomas show cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7ab38ee88e0dd63e3fcf818fff3db69
https://doi.org/10.1016/s0003-3928(16)30033-6

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