Zobrazeno 1 - 10
of 51
pro vyhledávání: '"I. Ghazzouli"'
Autor:
I. Ghazzouli, Yung-Chi Cheng, J.‐S. Feng, Shen Zy, George I. Birnbaum, V. Brankovan, G.‐D. Hsiung, J. Giziewicz, J.‐H. Yang, Mao-Chin Liu, Tai-Shun Lin, William H. Prusoff
Publikováno v:
ChemInform. 22
Autor:
Shen Zy, I. Ghazzouli, J. Giziewicz, Mao-Chin Liu, George I. Birnbaum, J.‐H. Yang, Brankovan, Yung-Chi Cheng, Tai-Shun Lin, William H. Prusoff
Publikováno v:
Journal of Medicinal Chemistry. 34:693-701
Various 3'-deoxy pyrimidine nucleoside analogues have been synthesized for evaluation as potential anticancer and antiviral agents. Among these compounds, 1-(3-deoxy-beta-D-threo-pentofuranosyl)cytosine (10, 3'-deoxy-ara-C) and 3'-deoxycytidine (22)
Autor:
D R, Tortolani, J W, Russell, V J, Whiterock, M J, Hitchcock, I, Ghazzouli, J C, Martin, M M, Mansuri, J E, Starrett
Publikováno v:
Journal of pharmaceutical sciences. 83(3)
A series of 5’-derivatives and modified pyrimidine analogues of 2’,3’-didehydro-3’-deoxythymidine (d4T, stavudine, 1) were synthesized to determine their potential as oral prodrugs of d4T. Utilizing a screen developed for the rapid evaluation
Autor:
J J, Bronson, L M, Ferrara, M J, Hitchcock, H T, Ho, K L, Woods, I, Ghazzouli, E R, Kern, K F, Soike, J C, Martin
Publikováno v:
Advances in experimental medicine and biology. 278
Autor:
H. Bachmayer, M. Bodenteich, W. Streicher, Brigitte Rosenwirth, Walter Hayden, Erich Wanek, I. Ghazzouli, Herfried Griengl, Stütz P
Publikováno v:
Journal of Medicinal Chemistry. 28:1679-1684
Syntheses of 5-(2-haloethyl)-2'-deoxyuridines, 5-(3-chloropropyl)-2'-deoxyuridines, and 5-(2-chloroethyl)-2'-deoxycytidine are described. The antiviral activities of these compounds were determined in cell culture against herpes simplex virus types 1
Publikováno v:
Antimicrobial agents and chemotherapy. 28(6)
A decrease in the in vitro sensitivity to acyclovir (ACV) was observed in successive isolates of herpes simplex virus type 1 from three immunocompromised patients during intravenous therapy with this drug. The ACV-resistant isolate from patient 1 was
Publikováno v:
Journal of medicinal chemistry. 32(8)
Several 2,5'-anhydro analogues of 3'-azido-3'-deoxythymidine (AZT), 3'-azido-2'3'-dideoxyuridine (AZU), 3'-azido-2'3'-dideoxy-5-bromouridine, 3'-azido-2',3'-dideoxy-5-iodouridine, and 3'-deoxythymidine and the 3'-azido derivative of 5-methyl-2'-deoxy
Publikováno v:
Cancer research. 36(2 pt 2)
A review of our current progress in C-type virus vaccine research is presented. This includes the findings of C-type virus or its antigen expressions in every naturally occurring tumor of two strains of "low-incidence" laboratory mice, the BALB/cCr m
Autor:
M M, Mansuri, J E, Starrett, I, Ghazzouli, M J, Hitchcock, R Z, Sterzycki, V, Brankovan, T S, Lin, E M, August, W H, Prusoff, J P, Sommadossi
Publikováno v:
Journal of medicinal chemistry. 32(2)
The nucleoside analogue 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine (d4T, 1) was prepared by ring opening of the 3',5'-anhydro compound 5. This method has been refined such that it can be used to prepare d4T on a large scale. The tripho
Publikováno v:
International Journal of Immunopharmacology. 7:389