Zobrazeno 1 - 10
of 47
pro vyhledávání: '"I. G. Young"'
Publikováno v:
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Interleukin 5 is expressed in type 2 T lymphocytes and has a key role in driving the differentiation, recruitment and activation of eosinophils. Mice with a null mutation in the interleukin 5 gene (IL-5 -/- mice) have altered type 2 immune responses
Publikováno v:
Journal of Clinical Investigation. 99:1064-1071
The mechanism of cooperation between IL-5 and eotaxin for the selective accumulation of eosinophils at sites of allergic inflammation is unknown. In this investigation we have used IL-5 deficient mice to define the relationship between this cytokine
Publikováno v:
The Journal of Immunology. 153:3466-3475
The TCATTT-containing element extending from -61 to -41 of the mouse IL-5 gene is highly conserved in the corresponding region of the granulocyte-macrophage colony-stimulating factor (GM-CSF) gene and has been previously shown to be involved in regul
Publikováno v:
The Journal of Immunology. 152:5691-5702
The signaling mechanisms that regulate lymphokine gene expression in the murine Th2 clone D10.G4.1 were investigated by comparing the steady state mRNA levels of six lymphokine genes in response to cellular treatment with various activators and inhib
Publikováno v:
Anaesthesia. 49:287-292
Summary Intra-operative patient controlled sedation with propofol (bolus dose 18 mg over 5.4 s; lockout period 1 min) has been compared 10 continuous propofol infusion (3.6 nig.kg−1.h−1) in a randoniised crossover study of 38 ASA 1 or 2 day surge
Publikováno v:
European journal of biochemistry. 268(10)
The major signalling entity of the receptors for the haemopoietic cytokines granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin-3 (IL-3) and interleukin-5 (IL-5) is the shared beta(c) receptor, which is activated by ligand-specific