Zobrazeno 1 - 10
of 14
pro vyhledávání: '"I. F. W. McDOWELL"'
Autor:
S E, Humphries, J A, Cooper, M, Seed, N, Capps, P N, Durrington, B, Jones, I F W, McDowell, H, Soran, H A W, Neil
Publikováno v:
Atherosclerosis
Background and aims Patients with familial hypercholesterolaemia (FH) have an elevated risk of coronary heart disease (CHD). Here we compare changes in CHD mortality in patients with heterozygous (FH) pre 1992, before lipid-lowering therapy with stat
Publikováno v:
Journal of Inherited Metabolic Disease. 22:243-246
Premature vascular disease and thrombosis are recognized complications in homocystinuria. Vascular disease in patients with homocystinuria affects both arterial and venous systems, with venous thrombosis as the major cause of death (Mudd et al 1985).
Autor:
I. F. W. McDowell, M. Andrikoula
Publikováno v:
Diabetes, obesitymetabolism. 10(4)
LDL has been widely recognized as the major atherogenic lipoprotein and designated as the primary target for prevention of coronary heart disease (CHD); however, there is growing evidence that other triglyceride-rich lipoproteins, such as very low-de
Publikováno v:
Circulation. 102
To the Editor: Verhaar and colleagues, in their recent article,1 report on improvement in forearm endothelial function after 4 weeks’ oral treatment with folic acid at a dose of 5 mg daily in 20 subjects. They used a randomized crossover design wit
Autor:
I. F. W. McDowell, M. Brownlee, Michael Bellamy, Robert G. Newcombe, M. W. Ramsey, Malcolm J. Lewis, C. Bones
Publikováno v:
Circulation. 98(18)
Background —Elevated plasma homocysteine is a risk factor for arteriosclerosis, but a cause-and-effect relationship remains to be fully established. Endothelial dysfunction, an early event in the atherogenic process, has been shown to be associated
Autor:
R. A. Still, I. F. W. Mcdowell
Plasma homocysteine is emerging as an important risk factor for cardiovascular disease. Measurement in clinical laboratories is feasible by several techniques, including HPLC. Of particular importance is the potential for treatment by dietary modific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f785de2b80e7a8db830646e50afe43
https://europepmc.org/articles/PMC500636/
https://europepmc.org/articles/PMC500636/
Autor:
M. F. Bellamy, I. F. W. McDowell
Publikováno v:
Journal of inherited metabolic disease. 20(2)
In homocystinuria homocysteine appears to be directly toxic to the vasculature, but in mild hyperhomocysteinaemia a cause and effect relationship remains unproven. Evidence for a causal role is derived from recent primate and human studies in which e
Autor:
Graham P. Feeney, P. A. L. Ashfield-Watt, Frank David John Dunstan, Mark Worwood, I. F. W. McDowell, Michael Leslie Burr
Publikováno v:
Heart. 90:939-940
The incidence of cardiovascular disease increases progressively with age in men and is more common in younger men than in women of similar age. The difference in incidence of cardiovascular disease between the sexes diminishes in the elderly, as the
Autor:
D. J. Tiller, Ian D. Caterson, Bruce M. Hall, David J. Handelsman, I. F. W. Mcdowell, John R. Turtle
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 91:802-807
Summary. Ovarian function was assessed in 24 women after renal transplantation who were treated either with cyclosporin A (10 patients) or with a combination of azathioprine and prednisone (14 patients) as immunosuppressive therapy. The different reg
Publikováno v:
The Journal of endocrinology. 95(3)
Hypogonadal (hpg) mice lack hypothalamic luteinizing hormone releasing hormone (LH-RH). Gonadotrophs from male hpg mice have been identified by immunocytochemistry for LH and quantitative electron microscopy allied with radioimmunoassay of the gonado