GFR estimation is complicated by a high incidence of non-steady-state serum creatinine concentrations at the emergency department

Autor: M. S. A. Niemantsverdriet, T. T. Pieters, I. E. Hoefer, M. C. Verhaar, J. A. Joles, W. W. van Solinge, W. M. Tiel Groenestege, S. Haitjema, M. B. Rookmaaker

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261977 (2021)

Background Acquiring a reliable estimate of glomerular filtration rate (eGFR) at the emergency department (ED) is important for clinical management and for dosing renally excreted drugs. However, renal function formulas such as CKD-EPI can give biase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7339a9e323d25879a4dd2249e6baf0
https://pubmed.ncbi.nlm.nih.gov/34965267

Optimization of large animal MI models : A systematic analysis of control groups from preclinical studies

Autor: P. P. Zwetsloot, L. H. J. A. Kouwenberg, E. S. Sena, J. E. Eding, H. M. den Ruijter, J. P. G. Sluijter, G. Pasterkamp, P. A. Doevendans, I. E. Hoefer, S. A. J. Chamuleau, G. P. J. van Hout, S. J. Jansen of Lorkeers

Publikováno v: Scientific Reports, 7(1). Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Zwetsloot, P P, Kouwenberg, L H J A, Sena, E S, Eding, J E, Den Ruijter, H M, Sluijter, J P G, Pasterkamp, G, Doevendans, P A, Hoefer, I E, Chamuleau, S A J, Van Hout, G P J & Jansen Of Lorkeers, S J 2017, ' Optimization of large animal MI models; a systematic analysis of control groups from preclinical studies ', Scientific Reports, vol. 7, no. 1 . https://doi.org/10.1038/s41598-017-14294-z
Scientific Reports

Large animal models are essential for the development of novel therapeutics for myocardial infarction. To optimize translation, we need to assess the effect of experimental design on disease outcome and model experimental design to resemble the clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b7478ec5bade973eec7c5519b0df41
https://dspace.library.uu.nl/handle/1874/356640

Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes

Autor: M. J. H. van Summeren, R. Nuboer, K. A. van Bekkum, Serge Prop, J. Woudstra, W. de Jager, Eric Kalkhoven, Can Keşmir, F. K. de Boer, H. J. van den Ham, Henk S. Schipper, I. E. Hoefer, I. M. H. Mombers, J. H. Kieft, Berent J. Prakken

Publikováno v: Diabetologia. 55:2800-2810

In adults, circulating inflammatory mediators and activated CD14(++) monocytes link obesity to its metabolic and cardiovascular complications. However, it is largely unknown whether these inflammatory changes already occur in childhood obesity. To su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb5235cc83e655e83b70e6d66723bcf
https://doi.org/10.1007/s00125-012-2641-y

54 Angiogenese en gentherapie

Autor: I. E. Hoefer, J. J. Piek

Publikováno v: Cardiologie ISBN: 9789031348299

Hoewel inmiddels steeds meer patienten kunnen worden behandeld met percutane coronaire interventies (PCI) of bypasschirurgie (coronary artery bypass grafting, CABG), blijft er een groot aantal patienten (~20%) over dat om verscheidene redenen (bijvoo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e76b0640fab945990b103a7dcbb20a75
https://doi.org/10.1007/978-90-313-7029-0_54