Výsledky vyhledávání - "I. Dienava-Verdoold"

Patient-derived monoclonal antibodies directed towards beta(2) glycoprotein-1 display lupus anticoagulant activity

Autor: P. G. De Groot, Jan Voorberg, Mariëtte Boon-Spijker, Koen Mertens, I. Dienava-Verdoold, B. de Laat, R. H. W. M. Derksen, H.-J. M. Brinkman

Publikováno v: Journal of thrombosis and haemostasis, 9(4), 738-747. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 9(4), 738-747. Wiley

Patients with antiphospholipid syndrome (APS) display a heterogeneous population of antibodies with beta(2) glycoprotein-1 (?(2)GP1) as the major antigen.We isolated and characterized human mAbs directed against ?(2)GP1 from the immune repertoire of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ef14fc7b1b80a7f54b1c01cac661cc
https://doi.org/10.1111/j.1538-7836.2011.04212.x

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Shear stress is required for the endocytic uptake of the factor VIII-von Willebrand factor complex by macrophages

Autor: I. Dienava-Verdoold, Alexander B. Meijer, Koen Mertens, Lydia Castro-Núñez, Eszter Herczenik

Publikováno v: Journal of thrombosis and haemostasis : JTH. 10(9)

Summary. Background: Low-density lipoprotein (LDL) receptor family members contribute to the cellular uptake of factor VIII. How von Willebrand factor fits into this endocytic pathway has remained poorly understood. Objectives: It has been suggested

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2dd9f826a79d841cb30b2625672e12
https://pubmed.ncbi.nlm.nih.gov/22812646

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Tissue factor pathway inhibitor is an inhibitor of factor VII-activating protease

Autor: Femke Stephan, I. Dienava-Verdoold, Alan E. Mast, Sacha Zeerleder, Lucien A. Aarden, Ingrid Bulder, Diana Wouters, H. Te Velthuis

Publikováno v: Journal of thrombosis and haemostasis, 10(6), 1165-1171. Wiley-Blackwell

Summary. Background: Factor VII-activating protease (FSAP) is a serine protease that circulates in plasma in its inactive single-chain form and can be activated upon contact with dead cells. When activated by apoptotic cells, FSAP leads to the releas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947dc8c1253fe2515fb9d3201acd199e
https://pubmed.ncbi.nlm.nih.gov/22449009

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Factor seven activating protease (FSAP): does it activate factor VII?

Autor: Koen Mertens, Alexander B. Meijer, I. Dienava-Verdoold, H.-J. M. Brinkman, Mariëtte Boon-Spijker, Fabian Stavenuiter

Publikováno v: Journal of thrombosis and haemostasis : JTH. 10(5)

Summary. Background: Factor seven activating protease (FSAP) was initially reported as an activator of single-chain urokinase-type plasminogen activator (scuPA) and factor VII (FVII). Subsequently, numerous additional substrates have been identified,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db1cdaf4555d4f7d812ebf75138ce43
https://pubmed.ncbi.nlm.nih.gov/22394423

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Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies

Autor: Ruben Bierings, I. Dienava-Verdoold, Astrid Kragt, Dorothee van Breevoort, Karine M. Valentijn, Jacqueline W.T.M. Klein Gebbinck, Jan Voorberg, Alexander B. Meijer, Jeroen Eikenboom, Ellen L. van Agtmaal, Anton J.G. Horrevoets, Bieuwke S. Dragt, Mar Fernandez-Borja

Publikováno v: Journal of Proteome Research, 11(5), 2925-2936. American Chemical Society
van Breevoort, D, van Agtmaal, E L, Dragt, B S, Gebbinck, J K, Dienava-Verdoold, I, Kragt, A, Bierings, R, Horrevoets, A J G, Valentijn, K M, Eikenboom, J C, Fernandez-Borja, M, Meijer, A B & Voorberg, J 2012, ' Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies ', Journal of Proteome Research, vol. 11, no. 5, pp. 2925-2936 . https://doi.org/10.1021/pr300010r
Journal of proteome research, 11(5), 2925-2936. American Chemical Society
Journal of Proteome Research, 11(5), 2925-2936

Vascular endothelial cells contain unique storage organelles, designated Weibel-Palade bodies (WPBs), that deliver inflammatory and hemostatic mediators to the vascular lumen in response to agonists like thrombin and vasopressin. The main component o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce276742366e350b9d07dae5aa7697ce
https://research.vumc.nl/en/publications/fa1c1ea3-9400-423d-9c50-2ceb011db419

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