Zobrazeno 1 - 10 of 24 pro vyhledávání: '"I. D. Algranati"'
1
Polyamine metabolism in Trypanosoma cruzi: studies on the expression and regulation of heterologous genes involved in polyamine biosynthesis
Autor: I. D. Algranati
Publikováno v: Amino Acids. 38:645-651
Biochemical studies have shown that Trypanosoma cruzi and Toxoplasma gondii are the only eukaryotic organisms so far described which are auxotrophic for polyamines. Both parasites are unable to carry out the de novo biosynthesis of putrescine, and th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45d8e76de9a63175521dd0f90183fee
https://doi.org/10.1007/s00726-009-0425-6
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2
Streptomycin bactericidal action is dependent on polyamine endogenous levels in E. coli
Autor: G B, Diniello, I D, Algranati, S H, Goldemberg
Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 44(3)
E. coli polyamine-supplemented and depleted cultures showed an important difference in survival to streptomycin; the bactericidal effect of the antibiotic was remarkably higher in cells with normal levels of polyamines. Similar results were observed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b254b1ad65ab6f41546e4cd2b419825
https://pubmed.ncbi.nlm.nih.gov/9620449
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3
Effect of polyamines on plasmid-mediated kanamycin resistance and kanamycin phosphotransferase gene expression in Escherichia coli
Autor: H G, Nastri, I D, Algranati
Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 42(5)
The emergence of kanamycin resistance in a polyamine-deficient mutant of E. coli transformed with a plasmid encoding the kanamycin phosphotransferase gene has been studied. The initial inhibition of growth and protein synthesis caused by the addition
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cea8248984af1d18a7b68ccab30c190
https://pubmed.ncbi.nlm.nih.gov/8832103
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4
Regulation of putrescine uptake in Leishmania mexicana promastigotes
Autor: N S, Gonzalez, I D, Algranati
Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 40(7)
Putrescine uptake of Leishmania mexicana promastigotes is tightly regulated by polyamine intracellular concentrations. This uptake, markedly stimulated after parasite treatment with alpha-difluoromethylornithine (DFMO) for 48 to 72 hrs., was strongly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e654fa4aeb2bc4d857fab6179fa6e7af
https://pubmed.ncbi.nlm.nih.gov/7849558
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5
Polyamines prevent DFMO-mediated inhibition of angiogenesis
Autor: Martin Monte, Davel L, I. D. Algranati, S. Klein, Maria A. Jasnis, E Sacerdote de Lustig
Tumor growth mainly depend on formation of new blood vessels. DFMO (α-difluoromethylornithine), an inhibitor of polyamine biosynthesis, inhibits tumor growth in many animal tumors. Our investigation was to evaluate the requirement of polyamines for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6cda0aab91d8f6b5b097b174cd2020
https://www.sciencedirect.com/science/article/abs/pii/0304383594900604
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6
Long-term treatment of tumor-operated mice with high doses of alpha-difluoromethylornithine
Autor: I. D. Algranati, S. Klein, A. Fuchs, E. S. Lustig
Publikováno v: Biology of the Cell. 58:233-237
Mice inoculated subcutaneously with a mammary adenocarcinoma M3cell suspension and submitted 10 to 15 days later to the surgical removal of primary tumors have been chosen in our laboratory as the experimental model to study the effect of several dru
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d39aaece8e3a44e14fc7b4504a24f9
https://doi.org/10.1111/j.1768-322x.1986.tb00510.x
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7
Polyamines and regulation of ornithine biosynthesis in Escherichia coli
Autor: I D Algranati, A A Cataldi
Publikováno v: J. BACTERIOL. 1989;171(4):1998-2002
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
The growth rate of several polyamine-deficient mutants of Escherichia coli was very low in minimal medium and increased markedly upon the addition of putrescine, spermidine, arginine, citrulline, or argininosuccinic acid. The endogenous content of po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97df119e4671dd19047d6a4c06280e79
https://doi.org/10.1128/jb.171.4.1998-2002.1989
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8
A probable new pathway for the biosynthesis of putrescine in Escherichia coli
Autor: A A Cataldi, I D Algranati
Publikováno v: Biochemical Journal. 234:617-622
Some cultures of Escherichia coli BGA8, a mutant unable to synthesize putrescine, showed a change of behaviour and could grow almost equally well in either the absence or the presence of polyamines after repeated periods of polyamine starvation. Expe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbf1764d44c13dfdfb0c9a5a5f984c0
https://doi.org/10.1042/bj2340617
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10
Mechanism of Puromycin Action: Fate of Ribosomes after Release of Nascent Protein Chains from Polysomes
Autor: M. E. Azzam, I. D. Algranati
Publikováno v: Proceedings of the National Academy of Sciences. 70:3866-3869
The exchange of ribosomal subunits during the release of growing polypeptide chains by puromycin has been investigated in a bacterial cell-free system engaged in protein synthesis. The addition of spermidine, used as a stabilizing agent of 70S monome
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5056955741d155e4205047afb4d47dde
https://doi.org/10.1073/pnas.70.12.3866
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