Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity

Autor: L. Olga, J.A. van Diepen, I. Bobeldijk-Pastorova, G. Gross, P.M. Prentice, S.G. Snowden, S. Furse, T. Kooistra, I.A. Hughes, M.H. Schoemaker, E.A.F. van Tol, W. van Duyvenvoorde, P.Y. Wielinga, K.K. Ong, D.B. Dunger, R. Kleemann, A. Koulman

Publikováno v: EBioMedicine, Vol 63, Iss , Pp 103198- (2021)

Background: Altered lipid metabolism in early life has been associated with subsequent weight gain and predicting this could aid in obesity prevention and risk management. Here, a lipidomic approach was used to identify circulating markers for future

Externí odkaz: https://doaj.org/article/551d7ad850e641199863b7bd8b868fa9

Irradiation of thorium-bearing molten fluoride salt in graphite crucibles

Autor: N.B. Siccama, E. Capelli, A.J. de Koning, G.I.A. Lippens, V. Bhimanadam, Ondřej Beneš, P.J. Baas, Mohamed Naji, D.A. Boomstra, R.J.M. Konings, P.R. Hania, I. Bobeldijk, Pavel Soucek, S. de Groot, C. Sciolla

Publikováno v: Nuclear Engineering and Design. 375:111094

Four fluoride fuel salt samples (78LiF-22ThF4) in graphite crucibles were irradiated in the HFR Petten for a duration of 508 Full Power Days under the name SALIENT-01 (SALt Irradiation ExperimeNT). Goal of the experiment was to gain experience with t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64c44ea3f83395e18872276ce2ba2a5b
https://doi.org/10.1016/j.nucengdes.2021.111094

Variable cartilage degradation in mice with diet-induced metabolic dysfunction : food for thought

Autor: Hans M.G. Princen, R. Kleemann, A.E. Kozijn, Susan Kühnast, Simon C. Mastbergen, F.P.J.G. Lafeber, Harrie Weinans, Reinout Stoop, Lobke Gierman, E.J. Pieterman, R.A. van der Heijden, F. van der Ham, Anne-Marie Zuurmond, A.M. van den Hoek, Martine C. Morrison, A. Van Koppen, I. Bobeldijk, P.M. Stavro, Petra Mulder

Publikováno v: Osteoarthritis and Cartilage, 26(1), 95. W.B. Saunders Ltd
Osteoarthritis and cartilage, 26(1), 95-107. ELSEVIER SCI LTD
Osteoarthritis and Cartilage, 1, 25, 95-107

Objective: Human cohort studies have demonstrated a role for systemic metabolic dysfunction in osteoarthritis (OA) pathogenesis in obese patients. To explore the mechanisms underlying this metabolic phenotype of OA, we examined cartilage degradation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b65a74b2fe861890953043093838cf6
https://dspace.library.uu.nl/handle/1874/363420

SPHERE: Irradiation of sphere-pac fuel of UPuO2−x containing 3% Americium

Autor: C. Sciolla, F. Delage, E. D’Agata, S. Kamer, I. Bobeldijk, R.A.F. Okel, S. Bejaoui, Joseph Somers, P.R. Hania, P.J. Baas, J. McGinley

Publikováno v: Nuclear Engineering and Design. 275:300-311

Americium is a strong contributor to the long term radiotoxicity of high activity nuclear waste. Transmutation by irradiation in nuclear reactors of long-lived nuclides like 241 Am is therefore an option for the reduction of radiotoxicity of waste pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc06a0c3f0ba568fc29b7376045f97e

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