Zobrazeno 1 - 10
of 37
pro vyhledávání: '"I. Blench"'
Autor:
Stephanie Barker, I Blench, Michael P. Jennings, Gail Payne, Maria Panico, Anne Dell, Mumtaz Virji, Katherine Makepeace, Elaine Stimson, E. Richard Moxon, Jon R. Saunders, Howard R. Morris
Publikováno v:
Molecular Microbiology. 17:1201-1214
Neisseria meningitidis pili are filamentous protein structures that are essential adhesins in capsulate bacteria. Pili of adhesion variants of meningococcal strain C311 contain glycosyl residues on pilin (PilE), their major structural subunit. Despit
Autor:
M Rangarajan, Brian S. Hartley, K S Siddiqui, Howard R. Morris, A Kitmitto, Maria Panico, I Blench
Publikováno v:
Biochemical Journal. 289:201-208
The pattern and kinetics of partial proteolysis of Arthrobacter D-xylose isomerase tetramer was studied in order to determine the flexibility of surface loops that may control its stability. It was completely resistant to trypsin, chymotrypsin and el
Publikováno v:
Molecular and Cellular Endocrinology. 83:85-92
Estradiol 17β-hydroxysteroid dehydrogenase (E 2 DH) is the enzyme responsible for the interconversion of estrone (E 1 ), and the more biologically potent steroid, estradiol (E 2 ), and has a crucial role in regulating breast tissue concentrations of
Autor:
Helen Ireland, J. M. Freyssinet, David A. Lane, R J Olds, Howard R. Morris, L. Grunebaum, E. Thompson, S. L. Thein, I. D. Walker, I Blench
Publikováno v:
British Journal of Haematology. 79:70-74
A female with recurrent thrombosis was found to have a functional abnormality of antithrombin, with a ratio of functional to immunological activity in plasma of approximately 50%. Crossed immunoelectrophoresis in the presence of heparin was normal, i
Autor:
R. Caso, D. A. Lane, E. A. Thompson, R. J. Olds, S. L. Thein, M. Panico, I. Blench, H. R. Morris, J. M. Freyssinet, M. Aiach, F. Rodeghiero and, G. Finazzi
Publikováno v:
British Journal of Haematology. 77:87-92
Antithrombin (AT) Vicenza has been previously identified as a functionally abnormal antithrombin associated with familial thrombosis (Finazzi et al, 1985). It binds normally to heparin, but loses its affinity following interaction with thrombin: it i
Autor:
Iain MacIntyre, Howard R. Morris, Sunil J. Wimalawansa, Anthony Etienne, Maria Panico, I Blench
Publikováno v:
Biochemical and Biophysical Research Communications. 167:993-1000
Human β-calcitonin gene-related peptide (β-hCGRP) was isolated and purified from spinal cord. The complete characterization of this material was based on definitive mass analysis by fast atom bombardment mass spectrometry together with gas phase se
Publikováno v:
Molecular and biochemical parasitology. 82(1)
Protein modification by isoprenylation is essential in mammals and other eukaryotes, but has not been demonstrated in the parasitic protozoa of the order kinetoplastida. A key regulatory enzyme of the mevalonate pathway, hydroxymethylglutaryl-coenzym
Autor:
Jon R. Saunders, Gail Payne, Elaine Stimson, Stephanie Barker, Maria Panico, Mumtaz Virji, Howard R. Morris, A. Dell, E. R. Moxon, I Blench
Pili, which are filamentous protein structures on the surface of the meningitis-causing organism Neisseria meningitidis, are known to be post-translationally modified with substituents that affect their mobility in SDS/PAGE and which might play a cru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8bd4dba1ced572b556a03f3ebef20c
https://europepmc.org/articles/PMC1217337/
https://europepmc.org/articles/PMC1217337/
Publikováno v:
Molecular and cellular endocrinology. 85(3)
Estradiol 17 beta-hydroxysteroid dehydrogenase acts to convert estrone to the biologically active estrogen, estradiol, in breast tumors and MCF-7 breast cancer cells in vitro. In this study we have examined the ability of albumin to influence the eff
Autor:
Gerald W. Hart, Maria Panico, Andrew J. Reason, Robert S. Haltiwanger, I Blench, Howard R. Morris, A. Dell
Publikováno v:
Glycobiology. 1(6)
In this paper we report the first application of fast atom bombardment mass spectrometry (FAB-MS) to O-linked N-acetylglucosamine (O-GlcNAc)-bearing glycopeptides. Using N-acetylgalactosamine (GalNAc)- and Gal-GalNAc-containing glycopeptides (isolate