Zobrazeno 1 - 10
of 123
pro vyhledávání: '"I. Beier"'
Autor:
Jiang Li, Toshifumi Sato, María Hernández-Tejero, Juliane I. Beier, Khaled Sayed, Panayiotis V. Benos, Daniel W. Wilkey, Abhinav Humar, Michael L. Merchant, Andres Duarte-Rojo, Gavin E. Arteel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Although liver transplantation (LT) is an effective therapy for cirrhosis, the risk of post-LT NASH is alarmingly high and is associated with accelerated progression to fibrosis/cirrhosis, cardiovascular disease and decreased survival. Lack
Externí odkaz:
https://doaj.org/article/abb9545801424a18bd94c2374937741d
Autor:
Toshifumi Sato, Kimberly Z. Head, Jiang Li, Christine E. Dolin, Daniel Wilkey, Nolan Skirtich, Katelyn Smith, Dylan D. McCreary, Sylvia Liu, Juliane I. Beier, Aatur D. Singhi, Ryan M. McEnaney, Michael L. Merchant, Gavin E. Arteel
Publikováno v:
Matrix Biology Plus, Vol 17, Iss , Pp 100127- (2023)
Although most work has focused on resolution of collagen ECM, fibrosis resolution involves changes to several ECM proteins. The purpose of the current study was twofold: 1) to examine the role of MMP12 and elastin; and 2) to investigate the changes i
Externí odkaz:
https://doaj.org/article/b4a3e19f54cd4396a9a5f48571ac9871
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3756-3767 (2021)
Occupational and environmental exposures to industrial chemicals are well known to cause hepatotoxicity and liver injury. However, despite extensive evidence showing that exposure can lead to disease, current research approaches and regulatory polici
Externí odkaz:
https://doaj.org/article/0ac4da00042b4a3994cd2f3d10c6e7fd
Autor:
Juliane I. Beier, Gavin E. Arteel
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3768-3778 (2021)
Liver diseases are considered to predominantly possess an inherited or xenobiotic etiology. However, inheritance drives the ability to appropriately adapt to environmental stressors, and disease is the culmination of a maladaptive response. Thus “p
Externí odkaz:
https://doaj.org/article/65d91a6abfcf4931b018756a57400252
Autor:
Yue Ge, Maribel Bruno, Maliha S Nash, Najwa Haykal Coates, Brian N Chorley, Matthew C Cave, Juliane I Beier
Publikováno v:
Toxicol Sci
Alterations in physiological processes in pancreas have been associated with various metabolic dysfunctions and can result from environmental exposures, such as chemicals and diet. It was reported that environmental vinyl chloride (VC) exposure, a co
Publikováno v:
Redox Biology, Vol 24, Iss , Pp - (2019)
Vinyl chloride (VC), an abundant environmental contaminant causes steatohepatitis at high levels, but is considered safe at lower (i.e., sub-OSHA) levels. However, we have previously shown that even lower VC levels exacerbate experimental nonalcoholi
Externí odkaz:
https://doaj.org/article/688ca73520fa4058af4a0c8b47f35fab
Autor:
Juliane I. Beier, Luping Guo, Swati Joshi-Barve, Jeffrey D. Ritzenthaler, Jesse Roman, Gavin E. Arteel
Publikováno v:
Annals of Hepatology, Vol 15, Iss 5, Pp 762-772 (2016)
Background. The regenerative capacity of the liver is critical for proper responses to injury. Fibrin extracellular matrix (ECM) deposition is a common response to insult and contributes to inflammatory liver injury. However, the role of this matrix
Externí odkaz:
https://doaj.org/article/ec5ba9c02e124c2eb11fb40091d20247
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 2477-2503 (2015)
Both Alcoholic Liver Disease (ALD) and alcohol-related susceptibility to acute lung injury are estimated to account for the highest morbidity and mortality related to chronic alcohol abuse and, thus, represent a focus of intense investigation. In gen
Externí odkaz:
https://doaj.org/article/a36d82ef0d874778ab5febdd14f7c571
Autor:
Silvia Liu, Liqing He, Olivia B. Bannister, Jiang Li, Regina D. Schnegelberger, Charis-Marie Vanderpuye, Andrew D. Althouse, Francisco J. Schopfer, Banrida Wahlang, Matthew C. Cave, Satdarshan P. Monga, Xiang Zhang, Gavin E. Arteel, Juliane I. Beier
Publikováno v:
Toxicology and Applied Pharmacology. 468:116514
Autor:
David A. Brenner, Hayato Hikita, Yuji Iimuro, Kenichi Ikejima, Tatiana Kisseleva, Keiko Iwaisako, Juliane I. Beier, Hidekazu Tsukamoto, Kazuyoshi Kon, Yuko Akazawa, Shunhei Yamashina, Gavin E. Arteel
Publikováno v:
Juntendo Medical Journal. 67:248-256