Zobrazeno 1 - 10
of 62
pro vyhledávání: '"I. A. Zhuravin"'
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
The amyloid cascade hypothesis of Alzheimer's disease (AD) postulates that accumulation in the brain of amyloid β-peptide (Aβ) is the primary trigger for neuronal loss specific to this pathology. In healthy brain, Aβ levels are regulated by a dyna
Externí odkaz:
https://doaj.org/article/0460458fca474cf68d857e0271b5ca10
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 52(5)
Changes in electrical activity of neocortex after prenatal hypoxia (day 14 of embryogenesis - E14, 7 % 02 for 3 hours) and these combined with intracortical microinjection of epileptogenic 4-aminopyridine (4-AP) have been studied in adult rats. We an
Autor:
D. S. Vasylev, D. I. Kozlova, N. M. Dubrovskaya, N. L. Tumanova, Natalia N. Nalivaeva, I. А. Zhuravin
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 51:480-484
Analysis of the effect of a caspase-3 inhibitor on the level of amyloid-degrading neuropeptidase neprilysin (NEP) in the cortex of rats exposed to prenatal hypoxia (7% О2, 3 h) on day 14 of embryonic development (E14) was performed. It was found tha
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 51(6)
Analysis of the effect of a caspase-3 inhibitor on the content of the amyloid-degrading neuropeptidase neprilysin (NEP) in the cortex of rats subjected to prenatal hypoxia (7% O2, 3 h) on the 14-th day of the embryonic development (E14) was performed
Publikováno v:
Journal of Neurochemistry. 81:9-13
By studying the effects of gangliosides (G) on learning and memory we have found that i.p. administration of G led to a decrease in AC activity in the cortex (Cx) and striatum (Str) as well as in the threshold of the sensitivity of striatal neurons t
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 51(2)
This study reports the dynamics of changes in postnatal ontogenesis of the activity of soluble and membrane-bound forms of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in sensorimotor cortex of rats as well as the pattern of their cha
Autor:
D S, Vasiliev, N L, Tumanova, I A, Zhuravin, K Kh, Kim, N Ya, Lukomskaya, L G, Magazanik, A V, Zaitsev
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 50(6)
Animal models of epilepsy are very diverse and are used to elucidate the mechanisms underlying epileptogenesis and seizures. A single administration of pentylenetetrazole (PTZ) induces seizures, however it does not increase risk of further developmen
Autor:
D S, Vasil'ev, N L, Tumanova, V V, Lavrent'eva, L A, Starshinova, E P, Zhabko, N Ia, Lukomskaia, I A, Zhuravin, L G, Magazanik
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 99(9)
We investigated in mice the relationship between convulsions and morphological changes of hippocampal neurons that arise in the development of pentylentetrazol (PTZ)-induced kindling. The kindling was caused by of 35 mg/kg PTZ i.p. 3 times a week for
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 99(11)
The aim of the work was the analysis of the changes in a number of labile synaptopodin-positi- ve dendritic spines in parietal cortex and the CA1 field of the hippocampus, which characterize plasticity of intracellular interaction, and of the memoriz
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 49(3)