Zobrazeno 1 - 10
of 428
pro vyhledávání: '"I. A. Macdonald"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Expanded toolkits for prokaryotic synthetic biology can enhance the dynamic range of gene expression. Here the authors move the eukaryotic transcription factor QF into E. coli and integrate it into genetic devices.
Externí odkaz:
https://doaj.org/article/44d1dd608d0e4d2182bc9fe6b9c31be6
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background A novel, high bioavailability oral, enteric coated tablet formulation of S-adenosylmethionine (MSI-195) has been developed for life science application. The present research reports on a Phase 1 study to (i) determine the safety o
Externí odkaz:
https://doaj.org/article/c6f1277238be4abc9d881d1c864779d4
Publikováno v:
British Journal of Surgery. 110
Introduction Satiety is regulated by behavioural and physiological mechanisms. This study aimed to investigate the effects of food ingestion on subjective satiety, gastric emptying, mesenteric blood flow, and blood glucose concentration. Methods Twen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b606bc660153248df1c1ac7cf7dfa2c4
https://doi.org/10.1093/bjs/znad101.032
https://doi.org/10.1093/bjs/znad101.032
Autor:
E J Simpson, S Althubeati, S Cordon, D Bush, C Hoad, S Eldeghaidy, P Gowland, I A Macdonald, D N Lobo
Publikováno v:
British Journal of Surgery. 110
Introduction Hormones released in response to nutrients in the gastrointestinal (GI) tract, act as physiological signals to regulate appetite and play a role in feeding behaviours. Altered secretion of these ‘appetite’ hormones after feeding in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cfe270c04d726be2f2c2f89617216ab
https://doi.org/10.1093/bjs/znad101.155
https://doi.org/10.1093/bjs/znad101.155
Publikováno v:
Journal of the Geological Society. 179
Well-exposed fluvio-deltaic deposits of the Middle Jurassic Ravenscar Group (Yorkshire coast) provide a direct analogue for North Sea reservoirs, but previous studies were restricted to a few accessible bays. This study used lidar and drone photogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33036bae7ac83b9cf582dfd96a9e6210
https://doi.org/10.1144/jgs2021-017
https://doi.org/10.1144/jgs2021-017
Publikováno v:
Journal of Psychiatric Research. 121:118-125
Early score fluctuation in double-blind, placebo-controlled studies may affect the reliability of the baseline measurement and adversely affect the eventual study outcome. We examined the effect of early score fluctuation during a 2-week double-blind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e09e200492e948e8b83ec87bbf17ab
https://doi.org/10.1016/j.jpsychires.2019.11.014
https://doi.org/10.1016/j.jpsychires.2019.11.014
Publikováno v:
Biogeosciences, Vol 2, Iss 3, Pp 295-309 (2005)
Geophysical, temperature, and discrete depth-stratified geochemical data illustrate differences between an actively venting mud volcano and a relatively quiescent brine pool in the Gulf of Mexico along the continental slope. Geophysical data, includi
Externí odkaz:
https://doaj.org/article/6a14e2b9769c48a7a83805013357e1ec
Publikováno v:
Journal of Diabetes, Metabolism and its Complications. :1-5
Purpose: This study investigated the basal activity, and cold-induced thermogenic response, of supraclavicular brown adipose tissue (BAT) under warm (23˚C) and cool (18˚C) ambient conditions using supraclavicular skin temperature as a measure of BA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d6130f896986f9801255be5ae0ef2e
https://doi.org/10.31487/j.jdmc.2019.01.02
https://doi.org/10.31487/j.jdmc.2019.01.02
Publikováno v:
Journal of Psychiatric Research. 107:86-96
We conducted a 6-week double-blind, placebo-controlled, augmentation study comparing the efficacy and safety of MSI-195 800 mg (a proprietary formulation of S-adenosylmethionine) or placebo added to ongoing antidepressant medication (ADT) in acutely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fe67a01ea4a6e48c49a323ea894891
https://doi.org/10.1016/j.jpsychires.2018.10.010
https://doi.org/10.1016/j.jpsychires.2018.10.010
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Expanding the genetic toolbox for prokaryotic synthetic biology is a promising strategy for enhancing the dynamic range of gene expression and enabling new engineered applications for research and biomedicine. Here, we reverse the current trend of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ef42ab48e8ea94d78725328fbc627e
https://pubmed.ncbi.nlm.nih.gov/34226549
https://pubmed.ncbi.nlm.nih.gov/34226549