Zobrazeno 1 - 10
of 62
pro vyhledávání: '"I. A. Chaban"'
Publikováno v:
Фармацевтичний журнал, Vol 1, Pp 17-25 (2021)
As a result of metabolic transformations of substances in the human body in the reactions of lipid peroxidation, reactive oxygen species are formed. Normally, the regulation of the production of activated oxygen metabolites and free radicals in human
Externí odkaz:
https://doaj.org/article/1cf91c6d8d734d81afce7f72454489e5
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 132-139 (2020)
In an effort to develop novel anti-inflammatory agents, a series of thiazolo[4,5-b]pyridines were synthesized and modified at the N3 position. The structures of the obtained compounds were confirmed by 1H NMR spectroscopy and elemental analysis. The
Externí odkaz:
https://doaj.org/article/242d7b3868fa42f2835fa3987cd0e259
Publikováno v:
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 12, Iss 2, Pp 129-134 (2019)
Condensed bicyclic systems with thiazolidine core being annulated to pyridine one occupy prominent place in medicinal chemistry because of their broad spectrum of pharmacological activities. So, the synthesis of new N3 substitutes thiazolo[4,5-b]pyri
Externí odkaz:
https://doaj.org/article/38c595cee4e84b48abcfbeb18b70aa47
Autor:
Y. E. Matiichuk, Olga Ya. Shyyka, I. G. Chaban, T. I. Chaban, Vasyl S. Matiychuk, Ihor Nektegayev, V. V. Ogurtsov
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 4, Pp 1035-1043 (2020)
The synthesis, anti-inflammatory and antioxidant properties of novel 5-hydroxy-7-methyl-3H-thiazolo[4,5-b]pyridin-2-one derivatives were discussed. Fused thiazolo[4,5-b]pyridin-2-ones were synthesized and modified at the N3, C5 and C6 positions of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15617c3d85fbc8d30180e54e279650d9
https://doi.org/10.17344/acsi.2019.5439
https://doi.org/10.17344/acsi.2019.5439
Publikováno v:
Фармацевтичний часопис. :11-17
Мета роботи. Здійснити синтез деяких тіазоло[4,3-b]хіназолінів та провести дослідження протизапальної активності новосинтезованих сполу
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a2976bf9e0abe7336dbd5d543ddb03
https://doi.org/10.11603/2312-0967.2020.4.11656
https://doi.org/10.11603/2312-0967.2020.4.11656
Autor:
Olexandra Komarytsya, Ihor Nektegaev, Vasyl S. Matiychuk, Iryna Myrko, T. I. Chaban, I. G. Chaban, V. V. Ogurtsov
Publikováno v:
Pharmacia 67(3): 121-127
Synthesis of novel N3 and C5 substituted thiazolo[4,5-b]pyridin-2-ones was carried out on the basis of [3+3]-cyclocodensation, acylation and alkylation reactions. The structures of the obtained compounds were confirmed by 1H NMR spectroscopy, and ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d346523255d6b9b13fd78a3d2ec63a
https://doi.org/10.3897/pharmacia.67.e38969
https://doi.org/10.3897/pharmacia.67.e38969
Publikováno v:
Russian Journal of Organic Chemistry. 56:813-818
The reactions of ethyl 1-aryl-4-(2-bromoacetyl)-5-methyl-1H-pyrazolocarboxylates with ortho-hydroxybenzonitrile and 4,6-dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile gave previously unknown 2-aryl-3-methylbenzofuro[3,2-b]pyrazolo[4,3-e]azepine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f5534e2f10c63db5bf09a0eec3edff4
https://doi.org/10.1134/s1070428020050139
https://doi.org/10.1134/s1070428020050139
Publikováno v:
Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 132-139 (2020)
In an effort to develop novel anti-inflammatory agents, a series of thiazolo[4,5-b]pyridines were synthesized and modified at the N3 position. The structures of the obtained compounds were confirmed by 1H NMR spectroscopy and elemental analysis. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5bbab9d13e0e1f8f49d988acce974e
http://ukrbiochemjournal.org/wp-content/uploads/2020/04/Chaban_2_20.pdf
http://ukrbiochemjournal.org/wp-content/uploads/2020/04/Chaban_2_20.pdf
Publikováno v:
Фармацевтичний часопис. :13-20
Мета роботи. Здійснити синтез 3-[5-(5,7-диметил-2-оксо-тіазоло[4,5-b]піридин-3-ілметил)-[1,3,4]оксодіазол-2-ілсульфаніл-пропіонової кислоти та її ам
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::149a0228059968c22fa723510bd14416
https://doi.org/10.11603/2312-0967.2019.3.10467
https://doi.org/10.11603/2312-0967.2019.3.10467
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 17, Iss 3, Pp 15-20 (2019)
Aim. To expand the synthetic potential of thiazolo[4,5-b]pyridines, study the reactivity and perform the pharmacological screening of the antioxidant activity of the novel compounds synthesized. Results and discussion. A series of novel 3-aryl-5-hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62a4ec0db26e66e41d259ce1c779be3
http://ophcj.nuph.edu.ua/article/view/ophcj.19.174239/177690
http://ophcj.nuph.edu.ua/article/view/ophcj.19.174239/177690