Zobrazeno 1 - 10
of 115
pro vyhledávání: '"I. A. Bass"'
Autor:
Anna Berenson, Ryan Lane, Luis F. Soto-Ugaldi, Mahir Patel, Cosmin Ciausu, Zhaorong Li, Yilin Chen, Sakshi Shah, Clarissa Santoso, Xing Liu, Kerstin Spirohn, Tong Hao, David E. Hill, Marc Vidal, Juan I. Fuxman Bass
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cooperativity and antagonism between transcription factors (TFs) can drastically modify their binding to regulatory DNA elements. While mapping these relationships between TFs is important for understanding their context-specific functions,
Externí odkaz:
https://doaj.org/article/7449c28685fe45b293b4edfe2955aed8
Autor:
Jeffrey Kuniholm, Elise Armstrong, Brandy Bernabe, Carolyn Coote, Anna Berenson, Samantha D Patalano, Alex Olson, Xianbao He, Nina H Lin, Juan I Fuxman Bass, Andrew J Henderson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009982 (2021)
HIV-1 establishes a persistent proviral reservoir by integrating into the genome of infected host cells. Current antiretroviral treatments do not target this persistent population of proviruses which include latently infected cells that upon treatmen
Externí odkaz:
https://doaj.org/article/e65535297290443082962053fc349f65
Autor:
Clarissa S. Santoso, Zhaorong Li, Jaice T. Rottenberg, Xing Liu, Vivian X. Shen, Juan I. Fuxman Bass
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Treatment of the cytokine release syndrome (CRS) has become an important part of rescuing hospitalized COVID-19 patients. Here, we systematically explored the transcriptional regulators of inflammatory cytokines involved in the COVID-19 CRS to identi
Externí odkaz:
https://doaj.org/article/cd86cc74fba14a2595e55e02e89eafb4
Autor:
Juan I Fuxman Bass, Carles Pons, Lucie Kozlowski, John S Reece‐Hoyes, Shaleen Shrestha, Amy D Holdorf, Akihiro Mori, Chad L Myers, Albertha JM Walhout
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 10, Pp 1-19 (2016)
Abstract Transcription factors (TFs) play a central role in controlling spatiotemporal gene expression and the response to environmental cues. A comprehensive understanding of gene regulation requires integrating physical protein–DNA interactions (
Externí odkaz:
https://doaj.org/article/a6b21d56d5cf41ec85dc315ca42fac2b
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Recent whole-genome sequencing studies have identified millions of somatic variants present in tumor samples. Most of these variants reside in non-coding regions of the genome potentially affecting transcriptional and post-transcriptional gene regula
Externí odkaz:
https://doaj.org/article/541f743735f74ae9be98e71140ee3434
Autor:
Xuan Anita He, Anna Berenson, Michelle Bernard, Chris Weber, Juan I. Fuxman Bass, Shannon Fisher
Craniosynostosis (CS) is a common congenital defect affecting more than 1/2000 infants. Infants with CS have a premature fusion of one or multiple cranial sutures resulting in restricted brain expansion. Single gene mutations account for 15-20% of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f89d82d24b40c9e9ca95092664db3f72
https://doi.org/10.1101/2022.09.01.506150
https://doi.org/10.1101/2022.09.01.506150
Autor:
I I Bass
Publikováno v:
Russian journal of linguistics: Vestnik RUDN, Vol 0, Iss 2, Pp 159-168 (2014)
Two Japanese benefactive constructions are explored in the article: converb form of the verb -te/-de plus kudasaru and converb form of the verb -te/-de plus kureru. Semantic verb subclasses, capable of generating those constructions, are analyzed. A
Externí odkaz:
https://doaj.org/article/ef93fa5037a8464092cb79c846df67ed
Autor:
Juan I. Fuxman Bass, Lu Ge, Sergei I. Grivennikov, Dietmar J. Kappes, Bernardo S. Reis, Jikun Zha, Yinfei Tan, H. Leighton Grimes, Suraj Peri, Emmanuelle Nicolas, Kyle Ferchen, Daniel Mucida, Philip Czyzewicz, Xiang Hua, Jayati Basu, Albertha J.M. Walhout, Kathy Q. Cai
Publikováno v:
Nature Immunology. 22:969-982
The transcription factor ThPOK (encoded by the Zbtb7b gene) controls homeostasis and differentiation of mature helper T cells, while opposing their differentiation to CD4+ intraepithelial lymphocytes (IELs) in the intestinal mucosa. Thus CD4 IEL diff
Publikováno v:
Nucleic Acids Research
Variable Number Tandem Repeats (VNTRs) are tandem repeat (TR) loci that vary in copy number across a population. Using our program, VNTRseek, we analyzed human whole genome sequencing datasets from 2,770 individuals in order to detect minisatellite V
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Single nucleotide variants (SNVs) located in transcriptional regulatory regions can result in gene expression changes that lead to adaptive or detrimental phenotypic outcomes. Here, we predict gain or loss of binding sites for 741 transcription facto