Zobrazeno 1 - 10
of 117
pro vyhledávání: '"I. A. Abramets"'
Publikováno v:
Медицинский вестник Юга России, Vol 12, Iss 1, Pp 24-32 (2021)
The efficacy of depressive disorders treatment is insufficient. It is explained by an incomplete understanding of both pathogenesis of depression and antidepressants mechanism action. An improvement of the treatment efficacy of depression disorders i
Externí odkaz:
https://doaj.org/article/93716046e1b84a32846ec8539ee85cc9
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 18-24 (2020)
Background. Treatment of depression disorders is insufficiently effectively. It uses for increasing of treatment efficiency empirical selected combinations of antidepressants with preparations of lithium and certain others, which possess cerebroprote
Externí odkaz:
https://doaj.org/article/8ac4bc5c6ae54fb2b6e46dbb0432d5fa
Publikováno v:
I.P. Pavlov Russian Medical Biological Herald. 26:351-359
Background. It was find out the cerebroprotective properties of diacamphe – (±)-cis-3-(2’-benzimidazolyl)-1,2,2-trimethylcyclopentan-carbonic acid hydrochloride in vivo experiments in the some models of brain injury. Aim. To investigate the neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91c8fb6fd89f710c4115a935f758540
https://doi.org/10.23888/pavlovj2018263351-359
https://doi.org/10.23888/pavlovj2018263351-359
Publikováno v:
I.P. Pavlov Russian Medical Biological Herald. 24:21-30
The rostral anterior cingulate cortex (ACC) is important unit of the brain default mode network. An operation of this network is overset in depressive disorders of different genesis. A hyperactivity of ACC marks this overset. Neurophysiological natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3aa5fbd70caffcb626ca67353d34d7
https://doi.org/10.17816/pavlovj2016221-30
https://doi.org/10.17816/pavlovj2016221-30
Publikováno v:
Research Results in Pharmacology 5(2): 49-55
Research Results in Pharmacology, Vol 5, Iss 2, Pp 49-55 (2019)
Research Results in Pharmacology, Vol 5, Iss 2, Pp 49-55 (2019)
Introduction: Ketamine has a fast, but short-term antidepressant effect. To support the therapeutic effect, repeated administrations of the drug are needed, which causes cognitive disorders. The drugs with cerebroprotective action can potentially int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffae9222a7641f38757e45ede316ca3
https://doi.org/10.3897/rrpharmacology.5.35530
https://doi.org/10.3897/rrpharmacology.5.35530
Autor:
D. V. Evdokimov, I. I. Abramets
Publikováno v:
I.P. Pavlov Russian Medical Biological Herald. 23:120-125
Slow appearance of therapeutic action and partial therapeutic efficiency of used today antidepressants demand otherwise approaches for creation on principle new antidepressants. One from prototypes such drugs is ketamine possessing by capacity fast t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb3bb2a7b1c3f1d1ef1c8deb4bad0cd
https://doi.org/10.17816/pavlovj20153120-125
https://doi.org/10.17816/pavlovj20153120-125
Autor:
Aleksey Anatol'yevich Khodakovskiy, Ruslan Grigor'yevich Red'kin, Leonid Borisovich Braverman, I. I. Abramets, D. V. Evdokimov, Ol'ga Vital'yevna Khodakovskaya, Sergey Yur'yevich Shtrygol'
Publikováno v:
Reviews on Clinical Pharmacology and Drug Therapy. 13:56-61
The mechanisms of the neuroprotective effect of 3,2’-spiro-pyrrolo-2-оxindole derivative (code number R-86) were investigated in hippocampal sections of rats by measuring the amplitude of postsynaptic potentials in pyramidal neurons. In vitro R-86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86478a896618e00618c1d395be6cd707
https://doi.org/10.17816/rcf13156-61
https://doi.org/10.17816/rcf13156-61
Autor:
Tamara O. Zayka, I. I. Abramets, Sergey V. Nalotov, D. V. Evdokimov, Yulia V. Sidorova, M. Gorky
Publikováno v:
Biological Markers and Guided Therapy. 2:79-88
Studies of hippocampal slices of rats were show that non-competitive blocker of the NMDA glutamate receptor Ketamine (10 µM) and a selective inhibitor of COX-2 Nimesulide (10 µM) decrease a brain damages caused by excitotoxic action of NMDA (50 µM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f630e0388b3b5984d635b01033d008a
https://doi.org/10.12988/bmgt.2015.5117
https://doi.org/10.12988/bmgt.2015.5117
Publikováno v:
Research in Neurology: An International Journal. :1-13
In experiments on rats was simulated the behavioral depression caused by social isolation and chronic inflammation. It was found in slices of the medial prefrontal cortex that behavioral depression was attained by the inhibition of the basal glutamat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d25870acd0b160386b5366e5af498211
https://doi.org/10.5171/2013.159123
https://doi.org/10.5171/2013.159123
Publikováno v:
Neurophysiology. 45:279-288
Experimental diabetes mellitus (EDM) was induced in rats by injections of alloxan (125 mg/kg); this disease was manifested in a rise in the mean level of glucose in the blood from 5.0 to 18.7 mM. On the 4th week of the development of EDM, rats demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921b362bc931eb5aac3436d01f690199
https://doi.org/10.1007/s11062-013-9369-2
https://doi.org/10.1007/s11062-013-9369-2