Zobrazeno 1 - 10
of 116
pro vyhledávání: '"I., Roach"'
Autor:
Latifa Alghfeli, Divyasree Parambath, Shaista Manzoor, Helmtrud I. Roach, Richard O.C. Oreffo, Ahmed T. El-Serafi
Publikováno v:
Bone Reports, Vol 15, Iss , Pp 101143- (2021)
Background: Efficient differentiation of stem cells into three-dimensional (3D) osteogenic construct is still an unmet challenge. These constructs can be crucial for patients with bone defects due to congenital or traumatic reasons. The modulation of
Externí odkaz:
https://doaj.org/article/dd329a1753794badbf3377318595f849
Publikováno v:
AIMS Agriculture and Food, Vol 4, Iss 1, Pp 136-148 (2019)
Approximately 4.5 billion people worldwide are negatively affected by mycotoxins, especially small-scale farmers in regions that do not have access to energy efficient and appropriately designed drying systems. Mycotoxins are produced by fungi tainti
Externí odkaz:
https://doaj.org/article/e52cf1a0d41d43068926188b56933fec
The Upper Darling Floodplain AEM Survey is part of the Exploring for the Future Program. This scientific research is being carried out to obtain data that will enhance understanding of the groundwater resources of the upper Darling River region. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::899662943261247472d9f784d5393b68
Autor:
María C de Andrés, Emmajayne Kingham, Kei Imagawa, Antonio Gonzalez, Helmtrud I Roach, David I Wilson, Richard O C Oreffo
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54957 (2013)
Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic impri
Externí odkaz:
https://doaj.org/article/407e616e20014b898ee83149c70e9107
Autor:
A. Cross, M.P. Doublier, I. Roach, K. Czarnota, P. Wynne, W. Jiang, A. Schofield, R.G. Skirrow, J. Murr, J. Duan, L. Pitt, A. Clark, J. Goodwin, A. O'Rourke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7853edd6019f81b9c39bf39a12c704ad
https://doi.org/10.11636/134444
https://doi.org/10.11636/134444
Autor:
Patrick Flaherty, Mala L Radhakrishnan, Tuan Dinh, Robert A Rebres, Tamara I Roach, Michael I Jordan, Adam P Arkin
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 9, p e1000185 (2008)
Macrophage cells that are stimulated by two different ligands that bind to G-protein-coupled receptors (GPCRs) usually respond as if the stimulus effects are additive, but for a minority of ligand combinations the response is synergistic. The G-prote
Externí odkaz:
https://doaj.org/article/67020bd7c4b647a4a7b7ede15a237b85
Autor:
Eiji Itoi, Richard O.C. Oreffo, Kei Imagawa, Ko Hashimoto, María C. de Andrés, Miguel Otero, Mary B. Goldring, Helmtrud I. Roach
Publikováno v:
Arthritis & Rheumatology. 66:3040-3051
Objective To investigate whether the changes in collagen gene expression in osteoarthritic (OA) human chondrocytes are associated with changes in the DNA methylation status in the COL2A1 enhancer and COL9A1 promoter. Methods Expression levels were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2549d0d049aa4fcc6cbff0e0866c0b75
https://doi.org/10.1002/art.38774
https://doi.org/10.1002/art.38774
Autor:
Antonio González, María C. de Andrés, Mary B. Goldring, Richard O.C. Oreffo, Ko Hashimoto, Helmtrud I. Roach, Kei Imagawa
Publikováno v:
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Servizo Galego de Saúde (SERGAS)
Idiopathic osteoarthritis (OA) is a late-onset, complex disease of the joint, characterized by progressive failure of the extracellular cartilage matrix, along with changes in the synovium and subchondral bone. A key feature of OA is the catabolic de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f81fa4b18edf298013c2d58269bf5b
https://doi.org/10.1002/art.37806
https://doi.org/10.1002/art.37806