Zobrazeno 1 - 10
of 313
pro vyhledávání: '"I-ju Chen"'
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 1, Pp 38-47 (2024)
Background: Immunomodulatory agents, such as tocilizumab (TCZ), exert promising effects against SARS-CoV-2 infection. However, growing evidence indicates that using TCZ may carry higher risks of secondary bloodstream infection (sBSI). This study dete
Externí odkaz:
https://doaj.org/article/e440fa8f60874966a30f9b3fb42c40e2
Autor:
Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou, Yu-Ching Hsieh, Ya-Chi Chang, Hsiao-Chen Huang, Zhi-Qin Li, Yuan-Chin Hsieh, I-Ju Chen, Bo-Cheng Huang, Yu-Cheng Su, Wen-Wei Lin, Hsin-Chieh Lin, Jui-I Chao, Shyng-Shiou F. Yuan, Yun-Ming Wang, Tian-Lu Cheng, Shey-Cherng Tzou
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-16 (2023)
Abstract Background CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG1 that is approved for treating rheumatoid arthritis. However, CTLA4Ig may induce adve
Externí odkaz:
https://doaj.org/article/04a6994390a54d96bd95a6eab38a44f9
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Engineering quantum states requires precise manipulations at the atomic level. Here, the authors use deep reinforcement learning to manipulate Ag adatoms on Ag surfaces, which combined with path planning algorithms enables autonomous atomic assembly.
Externí odkaz:
https://doaj.org/article/7bf6029542df4c3baecdb5278c8d57c8
Autor:
Yuan-Chin Hsieh, Jun-min Liao, Kuo-Hsiang Chuang, Kai-Wen Ho, Shih-Ting Hong, Hui-Ju Liu, Bo-Cheng Huang, I-Ju Chen, Yen-Ling Liu, Jaw-Yuan Wang, Hsiang-Lin Tsai, Yu-Cheng Su, Yen-Tseng Wang, Tian-Lu Cheng
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Humanization of mouse monoclonal antibodies (mAbs) is crucial for reducing their immunogenicity in humans. However, humanized mAbs often lose their binding affinities. Therefore, an in silico humanization method that can prevent t
Externí odkaz:
https://doaj.org/article/682be9e061ff404fb8b92628dae0d0c1
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Globally, obesity is a major health problem and can markedly increase the risk of various diseases, including type 2 diabetes mellitus, hypertension (HTN), dyslipidemia, and chronic kidney disease (CKD). The association of obesity-related parameters,
Externí odkaz:
https://doaj.org/article/9f819d2291a44b0c9c5546cfcfa07b3f
Autor:
Michael J Campbell, Hope S Rugo, Chiun-Sheng Huang, Chun-Yen Lin, Jung-Tung Hung, I-Ju Chen, Shir-Hwa Ueng, Shin-Cheh Chen, Mu-Yi Chen, Yung-Chang Lin, Alice L Yu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/89c1a2bb641f4bd6abe6049e9723de97
Autor:
Yi-An Cheng, Tung-Ho Wu, Yun-Ming Wang, Tian-Lu Cheng, I-Ju Chen, Yun-Chi Lu, Kuo-Hsiang Chuang, Chih-Kuang Wang, Chiao-Yun Chen, Rui-An Lin, Huei-Jen Chen, Tzu-Yi Liao, En-Shuo Liu, Fang-Ming Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Developing a universal strategy to improve the specificity and sensitivity of PEGylated nanoaparticles (PEG-NPs) for assisting in the diagnosis of tumors is important in multimodality imaging. Here, we developed the anti-methoxypo
Externí odkaz:
https://doaj.org/article/a1709e686d1b41b7aed8c1d16fb3348b
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundTraditional risk factors for chronic kidney disease (CKD) include diabetes mellitus (DM), hypertension (HTN), and metabolic syndrome, which are health conditions related to obesity. We aimed to investigate which of the three obesity indices
Externí odkaz:
https://doaj.org/article/a9de743f1d034573b018bf84fee49797
Autor:
Wen-Wei Lin, Kai-Wen Ho, Hsiang-Han Su, Tien-Fang Fang, Shey-Cherng Tzou, I-Ju Chen, Yun-Chi Lu, Mu-Shen Chang, Yun-Chen Tsai, En-Shuo Liu, Yu-Cheng Su, Yen-Tseng Wang, Tian-Lu Cheng, Hsin-Kai Huang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Fibrinogen-like protein 1 (FGL1) was recently identified as a major ligand of lymphocyte-activation gene-3 (LAG-3) on activated T cells and serves as an immune suppressive molecule for regulation of immune homeostasis. However, whether FGL1 has thera
Externí odkaz:
https://doaj.org/article/2f22afbac68e419987c354eef80b6a3e
Autor:
Mei-Chun Lu, I-Ju Chen, Le-Tien Hsu, Ying-Jen Chen, Meng-Ting Tsou, Tao-Hsin Tung, Jau-Yuan Chen
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: This study aimed to quantify the proportion of participants with chronic kidney disease (CKD) and associated metabolic risk factors in a middle-aged and elderly population in Guishan District, Taoyuan City, Taiwan.Methods: This cross-sect
Externí odkaz:
https://doaj.org/article/46d6aafdaa62489182fe8304480919d0