Zobrazeno 1 - 10
of 86
pro vyhledávání: '"I-Tong Mak"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210107 (2019)
We determined if HIV-1 expression in transgenic (HIV-1-Tg) rats enhanced hepatic genomic changes related to oxidative/nitrosative stress and lipogenesis during cART-treatment, and assessed effects of Mg-supplementation. A clinically used cART (atazan
Externí odkaz:
https://doaj.org/article/d4892e25a4ee46c5a3e056cc11b787f5
Autor:
Christopher F. Spurney, Micaela Iantorno, William B. Weglicki, I. Tong Mak, Joanna J. Chmielinska, Jay H. Kramer
Publikováno v:
Hearts. 1:117-125
The role of NADPH oxidase subunit, gp91phox (NOX2) in development of oxidative stress and cardiac dysfunction due to iron (Fe)-overload was assessed. Control (C57BL/6J) and gp91phox knockout (KO) mice were treated for up to 8 weeks with Fe (2.5 mg/g/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ccd28c0df315b6457326a652ba67f7
https://doi.org/10.3390/hearts1020012
https://doi.org/10.3390/hearts1020012
Autor:
Jay H. Kramer, I. Tong Mak
Publikováno v:
Hearts. 1:149-151
Cardiac injury manifested as either systolic or diastolic dysfunction is considered an important preceding stage that leads to or is associated with eventual heart failure (HF) [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1348877d8bd6555b48bf8a3fe81ee759
https://doi.org/10.3390/hearts1030015
https://doi.org/10.3390/hearts1030015
Autor:
Christopher F. Spurney, Jay H. Kramer, I. Tong Mak, William B. Weglicki, Terry M. Phillips, Joanna J. Chmielinska
Publikováno v:
Hearts
Volume 1
Issue 2
Pages 11-116
Volume 1
Issue 2
Pages 11-116
Hypomagnesemia occurs clinically as a result of restricted dietary intake, Mg-wasting drug therapies, chronic disease status and may be a risk factor in patients with cardiovascular disorders. Dietary restriction of magnesium (Mg deficiency) in anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfcb26561286e64303587790ae57207a
Autor:
Joanna J. Chmielinska, I-Tong Mak, Christopher F. Spurney, William B. Weglicki, Jay H. Kramer
Publikováno v:
Molecular and cellular biochemistry. 465(1-2)
Cutaneous changes like rash and hair loss, as well as other neurogenic inflammation side effects, occur frequently during anticancer treatment with the epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), erlotinib. These adverse ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea9efe7dacfde9d59e3db8bf239fac3
https://pubmed.ncbi.nlm.nih.gov/31853800
https://pubmed.ncbi.nlm.nih.gov/31853800
Publikováno v:
Isolated Adult Cardiomyocytes ISBN: 9780429290541
Isolated Adult Cardiomyocytes
Isolated Adult Cardiomyocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adbb90d09d7a8c33e11c6bc6bdbcaeb6
https://doi.org/10.1201/9780429290541-6
https://doi.org/10.1201/9780429290541-6
Autor:
Joanna J. Chmielinska, Jay H. Kramer, William B. Weglicki, Christopher F. Spurney, I. Tong Mak
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 8
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2409 (2018)
Volume 19
Issue 8
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2409 (2018)
Chronic effects of a combination antiretroviral therapy (cART = tenofovir/emtricitatine + atazanavir/ritonavir) on systemic and cardiac oxidative stress/injury in HIV-1 transgenic (Tg) rats and protection by Mg-supplementation were assessed. cART (lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3727393d413f83fa6aad6c600751f3d
https://pubmed.ncbi.nlm.nih.gov/30111743
https://pubmed.ncbi.nlm.nih.gov/30111743
Autor:
William B. Weglicki, I. Tong Mak, Christopher F. Spurney, Joanna J. Chmielinska, Jay H. Kramer
Publikováno v:
Journal of Cardiovascular Pharmacology. 65:54-61
To determine whether the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib may cause hypomagnesemia, inflammation, and cardiac stress, erlotinib was administered to rats (10 mg · kg(-1)· d(-1)) for 9 weeks. Plasma magnesium decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdaa878e19b80049e9b9964435dd766
https://doi.org/10.1097/fjc.0000000000000163
https://doi.org/10.1097/fjc.0000000000000163
Autor:
Xi Chen, I. Tong Mak
Publikováno v:
Free Radical Biology and Medicine. 69:77-85
Ritonavir (RTV), a prototypical protease inhibitor currently used as a key component of anti-HIV therapy, is known for its endothelial and hepatic toxicity. The effects of RTV and magnesium supplementation on cultured bovine endothelial cell (EC) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31d77f13c6b76cd18feab31d20d85c7
https://doi.org/10.1016/j.freeradbiomed.2014.01.011
https://doi.org/10.1016/j.freeradbiomed.2014.01.011
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210107 (2019)
PLoS ONE
PLoS ONE
We determined if HIV-1 expression in transgenic (HIV-1-Tg) rats enhanced hepatic genomic changes related to oxidative/nitrosative stress and lipogenesis during cART-treatment, and assessed effects of Mg-supplementation. A clinically used cART (atazan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db49dd6ba2d96f56a70851804fac0949
https://doi.org/10.1371/journal.pone.0210107
https://doi.org/10.1371/journal.pone.0210107