Zobrazeno 1 - 10
of 34
pro vyhledávání: '"I-Lu Lai"'
Autor:
Chung-Ming Huang, Yu-Chia Chen, I-Lu Lai, Hong-Da Chen, Po-Hao Huang, Siang-Jyun Tu, Ya-Ting Lee, Ju-Chen Yen, Chia-Li Lin, Ting-Yuan Liu, Jan-Gowth Chang
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Hyperuricemia and gout are two of the most common metabolic disorders worldwide; their incidence is increasing with changes in lifestyle, and they are correlated with many diseases, including renal and cardiovascular diseases. The majority of studies
Externí odkaz:
https://doaj.org/article/4ec10053b92c4368b0c9b7e33cedecc5
89
Hepatocellular transformation is a long-term process that requires chronic exposure to the harm of virus, alcohol or oxidative stress. Activator protein 1 (AP-1), a nuclear transcription factor, consists of Jun/Fos heterodimer or Jun/Jun homo
Hepatocellular transformation is a long-term process that requires chronic exposure to the harm of virus, alcohol or oxidative stress. Activator protein 1 (AP-1), a nuclear transcription factor, consists of Jun/Fos heterodimer or Jun/Jun homo
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/70480987890311018010
97
KAP1 (KRAB-association protein 1) is a transcriptional intermediary factor, which acts as a scaffold in many transcriptional regulation complexes. The recruitment of KAP1 by a large family of Kruppel-like zinc finger proteins (KRAB-ZFPs) to r
KAP1 (KRAB-association protein 1) is a transcriptional intermediary factor, which acts as a scaffold in many transcriptional regulation complexes. The recruitment of KAP1 by a large family of Kruppel-like zinc finger proteins (KRAB-ZFPs) to r
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/11960554554180661960
Publikováno v:
Oncology. 92:115-124
Objective: Oncogene-driven stress-related DNA damage has been observed in lesions of colon cancer. Furthermore, DNA sensors and nucleases are stimulated during active DNA damage and replication. However, their changes and influences with respect to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0dc1f75beaf4994133f1205adcb1e0
https://doi.org/10.1159/000452281
https://doi.org/10.1159/000452281
Autor:
Jan-Gowth Chang, Wen-Ling Chan, I-Lu Lai, Ya-Ting Lee, Shih-Ya Hung, Ju-Chen Yen, Ya-Sian Chang, Chin-An Yang
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3473 (2019)
Volume 20
Issue 14
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3473 (2019)
Volume 20
Issue 14
Gender affects cancer susceptibility. Currently, there are only a few studies on Y chromosome-linked long noncoding RNAs (lncRNAs), and the potential association between lncRNAs and cancers in males has not been fully elucidated. Here, we examined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f57905f86179fc731ab2183ac66d78
http://europepmc.org/articles/PMC6678590
http://europepmc.org/articles/PMC6678590
Autor:
I-Lu Lai, Joung-Liang Lan, Ju-Chen Yen, Jan-Gowth Chang, Chin-An Yang, Yu-Chia Chen, Ju-Pi Li, Yu-Chen Ho
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2806 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 9
International Journal of Molecular Sciences
Volume 19
Issue 9
Monocytes/macrophages are important in orchestrating inflammatory responses. However, knowledge of the long noncoding RNA (lncRNA) regulation of monocytic cell differentiation and diseases remains limited. We aimed to elucidate the role of the 17 kb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91437221cd8c0c714f36ba20b0ada57b
http://www.mdpi.com/1422-0067/19/9/2806
http://www.mdpi.com/1422-0067/19/9/2806
Autor:
Ya-Wen Cheng, Yen-Hao Su, Kuen Haur Lee, I-Lu Lai, Hsin-Yi Jiang, Wan-Chun Tang, Peik Sia, Chi-Chen Huang, Jun-Wei Lee, Ming-Heng Wu, Yi-Chao Lee
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853:2261-2272
There is a wide range of drugs and combinations under investigation and/or approved over the last decade to treat colorectal cancer (CRC), but the 5-year survival rate remains poor at stages II–IV. Therefore, new, more-efficient drugs still need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455fedcaac06aeab49b72cb6262795b6
https://doi.org/10.1016/j.bbamcr.2015.05.012
https://doi.org/10.1016/j.bbamcr.2015.05.012
Publikováno v:
Journal of Biological Chemistry. 290:20556-20564
PAX3 is a transcription factor critical to gene regulation in mammalian development. Mutations in PAX3 are associated with Waardenburg syndrome (WS), but the mechanism of how mutant PAX3 proteins cause WS remains unclear. Here, we found that PAX3 loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d03170981fad324ac1652f708c8bc49
https://doi.org/10.1074/jbc.m114.607713
https://doi.org/10.1074/jbc.m114.607713
Autor:
Ya-Sian Chang, Ju-Chen Yen, Ya-Ting Lee, Pei-Chin Lin, Chin-An Yang, Jan-Gowth Chang, Wen-Ling Chan, I-Lu Lai
Publikováno v:
Oncotarget
// I-Lu Lai 1, 8 , Chin-An Yang 2, 3, 4 , Pei-Chin Lin 5, 6, 7 , Wen-Ling Chan 1, 8 , Ya-Ting Lee 1 , Ju-Chen Yen 1 , Ya-Sian Chang 1, 2 and Jan-Gowth Chang 1, 2, 4 1 Epigenome Research Center, China Medical University Hospital, Taichung, Taiwan 2 De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a92e9c17e24acb648a4a086222ebb6
https://pubmed.ncbi.nlm.nih.gov/29228680
https://pubmed.ncbi.nlm.nih.gov/29228680