Zobrazeno 1 - 10
of 109
pro vyhledávání: '"I-Ling Lin"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Ubiquitination and deubiquitination are important forms of posttranslational modification that govern protein homeostasis. Deubiquitinating enzymes (DUBs), a protein superfamily consisting of more than 100 members, deconjugate ubiquitin chai
Externí odkaz:
https://doaj.org/article/be832de6c2344d1585efd96155d54739
Publikováno v:
Micro, Vol 3, Iss 2, Pp 578-590 (2023)
In this study, we developed polyethylene glycol-4000-based hydrogels for ketorolac tromethamine-controlled delivery systems through a free radical polymerization method. The developed hydrogels were subjected to FTIR, TGA, DSC, XRD, SEM, porosity ana
Externí odkaz:
https://doaj.org/article/eef8e746d4a24abaaf9797737aa0ded4
ATG4B and pS383/392-ATG4B serve as potential biomarkers and therapeutic targets of colorectal cancer
Autor:
Wan-Hsiang Hu, Ting-Ting Liu, Pei-Feng Liu, Paul Morgan, I-Ling Lin, Wei-Lun Tsai, Yi-Yun Cheng, Ang-Tsen Hsieh, Tsung-Hui Hu, Chih-Wen Shu
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Autophagy related protease 4B (ATG4B) is a protease required for autophagy processing, which is strongly implicated in cancer progression. Phosphorylation of ATG4B is crucial for activation of its protease activity. However, littl
Externí odkaz:
https://doaj.org/article/0be8ee22e46d479483caa93fbdd655fa
Autor:
Tsung-Ying Yang, Ya-Ju Hsieh, Li-Ting Kao, Guan Hong Liu, Shao-Hsuan Lian, Liang-Chun Wang, I-Ling Lin, Hsian-Yu Wang, Sung-Pin Tseng, Po-Liang Lu
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 1, Pp 86-94 (2022)
Background: Imipenem-relebactam is a new β-lactam and β-lactamase inhibitor combination to treat carbapenem-resistant gram-negative bacteria infections. However, difference in carbapenem resistant mechanisms existed with geographic variations. Obje
Externí odkaz:
https://doaj.org/article/a9c9c60ac01d4fe8bef9565abbfecbfc
Autor:
Ming-Yii Huang, Yi-Jung Huang, Tian-Lu Cheng, Wun-Ya Jhang, Chien-Chih Ke, Yi-Ting Chen, Shih-Hsun Kuo, I-Ling Lin, Yu-Hsiang Huang, Chih-Hung Chuang
Publikováno v:
Cells, Vol 12, Iss 11, p 1475 (2023)
5-FU-based chemoradiotherapy (CRT) and oxaliplatin-based CRT are commonly used therapies for advanced colorectal cancer (CRC). However, patients with a high expression of ERCC1 have a worse prognosis than those with a low expression. In this study, w
Externí odkaz:
https://doaj.org/article/5ef25a9c60a144e0b45a47a7c2918743
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1446 (2023)
Linalool is an aromatic oil with analgesic, anti-inflammatory and anti-UVB-induced skin damage effects. The aim of this study was to develop a linalool-loaded microemulsion formulation for topical application. In order to quickly obtain an optimal dr
Externí odkaz:
https://doaj.org/article/b62c3c8b40e64d44acf29a815dbc2f6b
Publikováno v:
Cancers, Vol 15, Iss 6, p 1776 (2023)
Pancreatic ductal adenocarcinoma (PDAC), the most common pancreatic malignancy, is an aggressive and lethal cancer with a dismal five-year survival rate. Despite remarkable improvements in cancer therapeutics, the clinical outcome of PDAC patients re
Externí odkaz:
https://doaj.org/article/533012ff139944cbbb71b722f2eed56b
Autor:
Muhammad Suhail, Chih-Wun Fang, I-Hui Chiu, Ming-Chia Hung, Quoc Lam Vu, I-Ling Lin, Pao-Chu Wu
Publikováno v:
Gels, Vol 8, Iss 8, p 521 (2022)
Acetaminophen is an odorless and white crystalline powder drug, used in the management of fever, pain, and headache. The half-life of acetaminophen is very short; thus, multiple intakes of acetaminophen are needed in a day to maintain a constant phar
Externí odkaz:
https://doaj.org/article/5bc11ee42e7f404988454115d8e20702
Autor:
Chia-Cheng Yu, Lih-Chyang Chen, Chih-Yung Chiou, Yu-Jia Chang, Victor C. Lin, Chao-Yuan Huang, I-Ling Lin, Ta-Yuan Chang, Te-Ling Lu, Cheng-Hsueh Lee, Shu-Pin Huang, Bo-Ying Bao
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background To determine the association between circadian pathway genetic variants and the risk of prostate cancer progression. Methods We systematically evaluated 79 germline variants in nine circadian pathway genes in a cohort of 458 patie
Externí odkaz:
https://doaj.org/article/c74ff266e82c4e078c57e3dd84528f6a
Publikováno v:
Gels, Vol 8, Iss 7, p 406 (2022)
Ibuprofen is an antipyretic and analgesic drug used for the management of different inflammatory diseases, such as rheumatoid arthritis and osteoarthritis. Due to a short half-life and rapid elimination, multiple doses of ibuprofen are required in a
Externí odkaz:
https://doaj.org/article/42272bef0dbb48aebc6e6541a2e28afc