Výsledky vyhledávání - "I Yu, Petrushanko"

[Blood-Brain Barrier Transwell Modeling]

Autor: A V, Petrovskaya, E P, Barykin, A M, Tverskoi, K B, Varshavskaya, V A, Mitkevich, I Yu, Petrushanko, A A, Makarov

Publikováno v: Molekuliarnaia biologiia. 56(6)

In vitro blood-brain barrier (BBB) modeling with the use of the brain endothelial cells grown on a transwell membrane is widely used to investigate BBB disorders and factors intended to ameliorate these pathologies. Endothelial cells, due to tight ju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90ddc92bb17d5626546a98ee54fb47fb
https://pubmed.ncbi.nlm.nih.gov/36475493

Zobrazit plný text záznamu

[Combination of RNase Binase and AKT1/2 Kinase Inhibitor Blocks Two Alternative Survival Pathways in Kasumi-1 Cells]

Autor: V A, Mitkevich, I Yu, Petrushanko, M G, Engelhardt, O I, Kechko, A A, Makarov

Publikováno v: Molekuliarnaia biologiia. 56(5)

Treatment of malignant neoplasms often requires the use of combinations of chemotherapeutic agents. However, in order to select combinations that are effective against specific tumor cells, it is necessary to understand the mechanisms of action of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab43e748e23dc75b01c2c79990115ece
https://pubmed.ncbi.nlm.nih.gov/36165015

Zobrazit plný text záznamu

Molecular Mechanisms of the Redox Regulation of the Na,K-ATPase

Autor: A. A. Makarov, Vladimir A. Mitkevich, I. Yu. Petrushanko

Publikováno v: Biophysics. 65:711-730

This review considers the molecular mechanisms involved in the redox regulation of the Na,K-ATPase. The enzyme creates a transmembrane gradient of sodium and potassium ions, which is necessary for the vital activity of all animal cells, and acts as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f041426819314707306f09aef94d8e92
https://doi.org/10.1134/s0006350920050139

Zobrazit plný text záznamu

Enhancement of Na,K-ATPase Activity as a Result of Removal of Redox Modifications from Cysteine Residues of the α1 Subunit: the Effect of Reducing Agents

Autor: Vladimir A. Mitkevich, Alexander A. Makarov, Rustam H. Ziganshin, E. A. Dergousova, I. Yu. Petrushanko, E. A. Klimanova, Olga D. Lopina

Publikováno v: Molecular Biology. 52:247-250

Na,K-ATPase is a transmembrane enzyme that creates a gradient of sodium and potassium, which is necessary for the viability of animal cells. The activity of Na,K-ATPase depends on the redox status of the cell, decreasing with oxidative stress and hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85135d708e6f945fa015f5dbdd673274
https://doi.org/10.1134/s0026893318020024

Zobrazit plný text záznamu

Isomerization of Asp7 increases the toxic effects of amyloid β and its phosphorylated form in SH-SY5Y neuroblastoma cells

Autor: E. P. Barykin, I. Yu. Petrushanko, K. M. Burnysheva, A. A. Makarov, V. A. Mitkevich

Publikováno v: Molecular Biology. 50:762-767

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6dea06857a9398543a17dad64857e23
https://doi.org/10.1134/s0026893316050034

Zobrazit plný text záznamu

Ribonuclease binase induces death in T-cell acute lymphoblastic leukemia cells by apoptosis

Autor: Vladimir S. Prassolov, Vladimir A. Mitkevich, P. V. Spirin, Alexander A. Makarov, I. Yu. Petrushanko, K. M. Burnysheva

Publikováno v: Molecular Biology. 50:302-306

Bacterial ribonuclease binase is a potential anticancer agent. In the present study, we have determined the toxic effect of binase towards cell lines of T-cell acute lymphoblastic leukemia Jurkat and CEMss. We have shown that binase induces apoptosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07257ced328a568facad98093dcb6f0c
https://doi.org/10.1134/s0026893316020035

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání