Zobrazeno 1 - 10
of 57
pro vyhledávání: '"I V Zarubina"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 153:336-339
Pronounced antihypoxic and antioxidant effects of preventive injection of succinic acid, aminothiol antihypoxants gutimine and amtizol, and succinate-containing aminothiol antihypoxants gutimine succinate and amtizol succinate to Wistar rats with acu
Autor:
I. V. Zarubina
Publikováno v:
Bulletin of Experimental Biology and Medicine. 145:47-50
The animals were adapted to intermittent hypoxic hypoxia in a flow pressure chamber for 3 days. Each one-day training session consisted of 4 elevations to an altitude of 6000 m for 20 min (15 m/sec, 20-min intervals between assents). Trekrezan (25 mg
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 78(8)
Experiments on rats divided into two groups (with high and low pain sensitivity) were used to assess the effect of tropalgin, a new derivative of tropine, in thermal pain tests (tail-flick and hot plate). Tropalgin was found to possess an analgesic e
Publikováno v:
Patologicheskaia fiziologiia i eksperimental'naia terapiia. 59(2)
Individual pain sensitivity of male Wistar rats was determined in a tail-flick model after action of focused thermal ray (flick) on tail. Rats with latency less than 5 sec were qualified as high sensitive (HS) to pain, more than 10 sec as low sensiti
Autor:
P. D. Shabanov, I. V. Zarubina
Publikováno v:
Bulletin of experimental biology and medicine. 160(4)
Experiments on rats showed that neurospecific protein preparations reduce the severity of neurological deficit, restore the structure of individual behavior of the animals with different hypoxia tolerance, and exert antioxidant action during chronic
Publikováno v:
Bulletin of Experimental Biology and Medicine. 142:205-208
Trekrezan in a dose of 25 mg/kg normalized the lymphocyte immune status and produced an energy-stabilizing effect, which manifested in decreased levels of lactate, ADP, and AMP and increased content of pyruvate and ATP in blood lymphocytes and lung t
Publikováno v:
Bulletin of Experimental Biology and Medicine. 140:752-755
A mathematical model is developed, which predicts the maximum deviation of adenine nucleotide content from the normal and the period of its restoration in the brain of animals. This model diminishes labor expenditures and duration of experimental stu
Publikováno v:
Bulletin of Experimental Biology and Medicine. 138:58-62
Monotherapy of consequences of craniocerebral trauma with pyrazidol (1 mg/kg) produced an anxiolytic effect in animals highly resistant to hypoxia and activating effect on low resistant animals. Treatment with bemitil in a dose of 25 mg/kg produced a
Autor:
P. D. Shabanov, I. V. Zarubina
Publikováno v:
Bulletin of experimental biology and medicine. 160(2)
The antioxidant effects of individual or combined application of polyoxidonium and metaprot were examined in rats with acute bronchopulmonary inflammation. By degree of antioxidant potency, polyoxidonium was inferior to metaprot, but their combined a
Publikováno v:
Journal of obstetrics and women's diseases. 48:43-47
The results of the carried out clinical approbation of a preparation have shown, that at term pregnancy in complex therapy of chronic fetal hypoxia caused with gestosis, the inclusion of bemithyl is expedient. The reception of a preparation within 5