Zobrazeno 1 - 10
of 17
pro vyhledávání: '"I V Kashparov"'
Autor:
K. B. Ignatov, I V Kashparov, E. A. Sokolova, T. S. Zamolodchikova, O D Kotsareva, A D Pemberton, A N Andrianov, E. V. Smirnova
Publikováno v:
Biochemistry (Moscow). 70:672-684
Mammalian serine proteases such as the chromosome 14 (Homo sapiens, Mus musculus) located granzymes, chymases, cathepsin G, and related enzymes including duodenase collectively represent a special group within the chymotrypsin family which we refer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702cd222dfd4e1d0af940a172f76d575
https://doi.org/10.1007/s10541-005-0168-2
https://doi.org/10.1007/s10541-005-0168-2
Publikováno v:
Molecular Biology. 36:754-759
The method of molecular dynamics in explicit solvent was applied to test the hypothesis of the existence of a self-inhibited form of chymosin in solution. The paths and energies were calculated for chymosin in solution and in a crystalline environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dba3cac4e15baa0ac63e1ce699d2ec6
https://doi.org/10.1023/a:1020644018474
https://doi.org/10.1023/a:1020644018474
Publikováno v:
Russian Journal of Bioorganic Chemistry. 28:28-37
An algorithm was proposed for the representation of biopolymer structures in an internal coordinate system (so-called structure regularization) by minimizing the target function using a flexible weighting coefficient scheme with three components that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1a5392fd2c5612720dbfdf8a3f724fb
https://doi.org/10.1023/a:1013950118719
https://doi.org/10.1023/a:1013950118719
Publikováno v:
Molekuliarnaia biologiia. 36(5)
The method of molecular dynamics in explicit solvent was applied to test the hypothesis of the existence of a self-inhibited form of chymosin in solution. The paths and energies were calculated for chymosin in solution and in a crystalline environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cc198822bd6874e1381aafdd829b6e0
https://pubmed.ncbi.nlm.nih.gov/12391857
https://pubmed.ncbi.nlm.nih.gov/12391857
Publikováno v:
Bioorganicheskaia khimiia. 28(1)
An algorithm for the representation of biopolymer structures in an internal coordinate system (so-called structure regularization) by minimizing the target function with a flexible weighting coefficient scheme using three components that determine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d709aa0214c7fccf29210247d1be569
https://pubmed.ncbi.nlm.nih.gov/11875971
https://pubmed.ncbi.nlm.nih.gov/11875971
Publikováno v:
Bioorganicheskaia khimiia. 25(12)
A computer model of a noncovalent complex of HIV-1 aspartyl protease with substrate-like inhibitor JG-365 was a priori constructed by using the approaches of theoretical conformational analysis and molecular mechanics. The root mean square deviation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e8f7d82828c1b34de6bdbfd75a8a644
https://pubmed.ncbi.nlm.nih.gov/10734551
https://pubmed.ncbi.nlm.nih.gov/10734551
Publikováno v:
Bioorganicheskaia khimiia. 25(8)
The conformational states of side chains of catalytic Asp residues in active sites of HIV-1 protease and rhizopuspepsin in the potential field of free enzymes were studied by using theoretical conformational analysis. Structural factors that stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d53235a9f3bdfce2a75bbb3ef3fe0cb8
https://pubmed.ncbi.nlm.nih.gov/10578465
https://pubmed.ncbi.nlm.nih.gov/10578465
Publikováno v:
Molekuliarnaia biologiia. 33(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f65b663daff5616df614af33eb2db35
https://pubmed.ncbi.nlm.nih.gov/10519125
https://pubmed.ncbi.nlm.nih.gov/10519125
Publikováno v:
Bioorganicheskaia khimiia. 25(6)
On the basis of theoretical conformational analysis of separate peptide fragments, the conformational characteristics of two substrates and a substrate-like inhibitor of aspartic protease rhizopuspepsin were studied. It was shown that the spatial str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78d60b08df11094c47a0675aed19b4d9
https://pubmed.ncbi.nlm.nih.gov/10505230
https://pubmed.ncbi.nlm.nih.gov/10505230
Publikováno v:
Bioorganicheskaia khimiia. 25(6)
A set of conformations was shown to be characteristic of the free-state spatial structure of substrate-like inhibitor JG-365 for aspartic protease from HIV-1. Among them, the lowest-energy conformations have a folded form of the peptide backbone. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6903f228e77256f12790ac65920e922e
https://pubmed.ncbi.nlm.nih.gov/10505229
https://pubmed.ncbi.nlm.nih.gov/10505229