Zobrazeno 1 - 10
of 45
pro vyhledávání: '"I V Botezatu"'
Autor:
I V Botezatu, T T Valiev, T E Dushenkina, K V Smirnova, R S Ravshanova, D M Maksimovich, A V Likhtenstein, V E Gurtsevich, A V Popa, N B Senyuta
Publikováno v:
Современная онкология, Vol 20, Iss 1, Pp 23-28 (2018)
Classical Hodgkin's lymphoma (cHL) is one of the many malignant tumors associated with the Epstein-Barr virus (EBV). It is shown that EBV-positive cases of cHL are distributed with different frequencies among all cases of the disease. The frequency o
Externí odkaz:
https://doaj.org/article/a40a19fc5879483a80f722e09ee097b0
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 2, Pp 85-96 (2024)
Introduction. Local hypermethylation of gene promoters and global genome hypomethylation are well-known manifestations of aberrant methylation associated with carcinogenesis. We investigated this phenomenon as a possible diagnostic marker for liquid
Externí odkaz:
https://doaj.org/article/4e20dce98b7a448881c700f72d25f03b
Epstein-Barr virus in Adygeans and Slavs in Russia: virus types, LMP1 variants, and malignant tumors
Autor:
K. V. Smirnova, N. B. Senyuta, A. K. Lubenskaya, I. V. Botezatu, T. E. Dushenkina, A. V. Lichtenstein, V. E. Gurtsevich
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 3, Pp 49-59 (2022)
Introduction. It is known that the structural features of the Epstein-Barr virus (EBV) affect the manifestation of its biological properties. Based on differences in the sequences of the EBNA2, EBNA3A, -B, and -C genes, two types of the virus, EBV-1
Externí odkaz:
https://doaj.org/article/278028c1d892436eb84360d51e42175c
Publikováno v:
Успехи молекулярной онкологии, Vol 8, Iss 4, Pp 53-60 (2021)
Introduction. Hypermethylated CpG islands in the promoters of suppressor genes (in particular, SEPT9) are clinically significant markers of malignant growth that are widely used in liquid biopsy. Real-time polymerase chain reaction with methylation-s
Externí odkaz:
https://doaj.org/article/40b7f50f559b42828e1acc5d4ab2c727
Autor:
K. V. Smirnova, N. B. Senuta, I. V. Botezatu, A. V. Ignatova, T. E. Dushenkina, A. A. Zolotarev, A. V. Lichtenstein, V. E. Gurtsevich
Publikováno v:
Успехи молекулярной онкологии, Vol 8, Iss 3, Pp 14-24 (2021)
Introduction. Epstein–Barr virus (EBV) is equally widespread in the endemic and non-endemic world regions for nasopharyngeal cancer (NPC). High incidence of NPC in endemic countries and low in non-endemic countries suggest there are different mecha
Externí odkaz:
https://doaj.org/article/10bee2d47671466f9d54ff67011fb776
Autor:
V. E. Gurtsevitch, K. V. Smirnova, I. V. Botezatu, T. E. Dushenkina, A. K. Lubenskaya, E. Dubar, N. B. Senyuta, A. V. Lichtenstein, S. V. Petrov
Publikováno v:
Инфекция и иммунитет, Vol 10, Iss 2, Pp 347-358 (2020)
Objective: To compare genetic structure of the main Epstein–Barr virus (EBV) oncogene, latent membrane protein 1 (LMP1), in EBV strains circulating in two genetically distinct ethnic populations in Russian Federation, Tatars and Slavs, as well as a
Externí odkaz:
https://doaj.org/article/14c779e423164006b51ddbbdfd32e626
Autor:
N. L. Lazarevich, P. M. Abramov, M. D. Fedorova, I. F. Kustova, D. A. Shavochkina, A. N. Katargin, N. P. Kisseljova, N. A. Dyakova, I. V. Botezatu, V. N. Kondratova, N. E. Kudashkin, Yu. I. Patyutko, A. V. Lichtenstein, S. V. Vinokurova
Publikováno v:
Успехи молекулярной онкологии, Vol 6, Iss 4, Pp 26-37 (2019)
Background. Over 600,000 people die from hepatocellular carcinoma (HCC) each year worldwide. The disease is often detected at advanced stages and in many cases is not curable. Early diagnostic and monitoring of HCC recurrences remains a substantial p
Externí odkaz:
https://doaj.org/article/9b93f0f531864f19b1a7a465474f40d0
Autor:
K. V. Smirnova, N. B. Senyuta, I. V. Botezatu, T. E. Dushenkina, A. K. Lubenskaya, A. A. Frolovskaya, S. V. Petrov, A. V. Lichtenstein, V. E. Gurtsevitch
Publikováno v:
Успехи молекулярной онкологии, Vol 5, Iss 3, Pp 65-74 (2018)
Objective of the investigation was to study the infection of ethnic Tatars with the Epstein–Barr virus (EBV) and to analyze the genetic structure of the oncogene of the virus, the latent membrane protein 1 (LMP1), in the virus strains of Tatar orig
Externí odkaz:
https://doaj.org/article/67f32287ea8548ea9d6c990016eb635d
Autor:
I. V. Botezatu, I. O. Panchuk, A. A. Kolomeytseva, A. A. Fedenko, N. N. Mazurenko, I. V. Tsyganova, O. Yu. Susova, V. N. Kondratova, V. P. Shelepov, A. V. Lichtenstein
Publikováno v:
Успехи молекулярной онкологии, Vol 5, Iss 1, Pp 35-42 (2018)
Objective: to evaluate the possibility of using a highly sensitive method of “enriched” polymerase chain reaction followed by DNA melting analysis (PCR-DMA) for target liquid biopsy of cancer patients.Materials and methods. The “enriched” PCR
Externí odkaz:
https://doaj.org/article/c36a853db30e43719f641e0ebe646d81
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 1, Pp 46-52 (2017)
Polymerase chain reaction (PCR) followed by DNA melting analysis with TaqMan probes effectively reveals mutations in the human genome “hot” spots. The necessity to carry out PCR in the asymmetric variant causes, however, a number of restrictions
Externí odkaz:
https://doaj.org/article/9c127f68d9e04a8881d1b8d9bd37806b