Výsledky vyhledávání - "I V, Kutiavin"

[Selective stabilization of AT-rich DNA duplexes by oligodeoxyribonucleotide conjugates with distamycin analogues]

Autor: A N, Siniakov, V A, Riabinin, S V, Seregin, S G, Lokhov, I V, Kutiavin, H B, Gamper, R B, Mayer

Publikováno v: Bioorganicheskaia khimiia. 23(7)

Oligodeoxyribonucleotide conjugates with distamycin analogues containing up to five pyrrolecarboxamide moieties were synthesized. The stability of duplexes formed by these conjugates was shown to depend directly upon the number of pyrrolecarboxamide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e7c2f0fa3bf52a3d4888647e9d163439
https://pubmed.ncbi.nlm.nih.gov/9471974

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[Effect of the intercalating dyes ethidium and phenazine, covalently jointed to the 5'- or 3'-end of the pentanucleotide d(pGAAAG), on the thermodynamics of complementary and cooperative interaction]

Autor: S G, Lokhov, A A, Koshkin, I V, Kutiavin, M P, Mitiakin, M A, Podyminogin, A V, Lebedev

Publikováno v: Bioorganicheskaia khimiia. 21(3)

Thermal stability was studied and thermodynamic parameters of complex formation were calculated for pentanucleotide complexes [formula: see text] and corresponding complexes of pentanucleotide derivatives carrying at their 5'- or 3'-ends covalently b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::956ef89ee63335d493b30ac35ff813f7
https://pubmed.ncbi.nlm.nih.gov/7763318

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[Site-directed chemical restriction of a single-stranded DNA fragment by an alkylating derivative of the tetranucleotide d(pApGpCpA) in the presence of tetranucleotide effectors]

Autor: V F, Zarytova, I V, Kutiavin, S V, Mamaev, M A, Podyminogin

Publikováno v: Bioorganicheskaia khimiia. 18(7)

Alkylation of a single-stranded DNA 302-mer by a 5'-O-phosphoryl-[4-(N-2-chloroethyl-N-methylamino)benzyl]amide derivative of the tetradeoxyribonucleotide d(pApGpCpA) in the presence of 3',5'-di-N-(2-hydroxyethyl) phenazinium derivatives of tetranucl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc3598fdd5123f4ba37c267ae0a08bdb
https://pubmed.ncbi.nlm.nih.gov/1445426

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[Effective selective modification of a single-stranded fragment of DNA with alkylating derivatives of short oligodeoxyribonucleotides in the presence of reaction effectors N-(2-hydroxyethyl)phenazine derivatives of oligodeoxyribonucleotides]

Autor: V F, Zarytova, I V, Kutiavin, S V, Mamaev, M A, Podyminogin

Publikováno v: Bioorganicheskaia khimiia. 16(12)

Tri-, tetra-, penta- and hexanucleotides bearing a reactive 4-(N-methylamino-N-2-chloroethyl)benzylamide group can effectively and selectively modify a single-stranded DNA fragment (302 nucleotides) in the presence of effectors, N-(2-hydroxyethyl)phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10da0a3ebb5c780a89b9cfb4204b01f4
https://pubmed.ncbi.nlm.nih.gov/2090116

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[Study of the spatial structure of the duplex d(pTGTTTGGC) d(pCCAAAC)A in aqueous solution by methods of uni- and two-dimensional (1)H-NMR spectroscopy and organic molecular mechanics]

Autor: E V, Bichenkova, Iu N, Vorob'ev, I V, Kutiavin, A V, Lebedev, T V, Mal'tseva, E Iu, Ténné

Publikováno v: Bioorganicheskaia khimiia. 16(9)

Structure of the complementary complex d(pTGTTTGGC) d(pCCAAAC)A in the aqueous solution has been investigated by one- and two-dimensional 1H NMR spectroscopy. The resonances of nonexchangeable protons of bases as well as methyl and deoxyribose 1', 2'

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ccb6f11dffa96242777d8af4983039b
https://pubmed.ncbi.nlm.nih.gov/2080930

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[Photomodification of nucleic acids by N-(2-hydroxyethyl)phenazine derivatives of oligonucleotides]

Autor: V F, Zarytova, I V, Kutiavin, T V, Mal'tseva, S V, Mamaev, V P, Mal'tsev

Publikováno v: Bioorganicheskaia khimiia. 16(5)

Photomodification of a 302-membered single-stranded DNA fragment by 5'-mono- and 3',5'-di-N-(2-oxyethyl)phenazine (Phn) derivatives of oligonucleotides has been investigated. Under strong laser irradiation (lambda 532 nm; power density 2,5 GV/cm2, ir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e6f88c4818f3e63dc7d7b4fbd1b1357
https://pubmed.ncbi.nlm.nih.gov/2400406

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[The cooperative interaction of oligonucleotides in duplexes with a single-chain break]

Autor: T V, Abramova, V V, Gorn, I V, Kutiavin, A V, Lebedev, S G, Lokhov, M A, Podyminogin

Publikováno v: Doklady Akademii nauk SSSR. 315(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b9daeefc23096bdab4447e4b11978c9
https://pubmed.ncbi.nlm.nih.gov/2088699

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Complementary addressed reagents carrying EDTA-Fe(II) groups for directed cleavage of single-stranded nucleic acids

Autor: M.A. Podyminogin, Valentin V. Vlassov, I. V. Kutiavin, A.S. Boutorin, S.A. Kazakov

Publikováno v: FEBS Letters. 172:43-46

An octathymidylate derivative carrying an EDTA residue at its 5'-terminus was synthesized. In the presence of Fe2+, O2 and dithiotreitol, this derivative cleaves poly(dA) and poly(A) more efficiently than the non-complementary polynucleotide poly(dT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5963fed0ea1858fdddd9419645c7fc
https://doi.org/10.1016/0014-5793(84)80869-8

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[Interaction of alkylating oligonucleotide derivatives with mammalian cells. A study of the uptake mechanism of derivative cells]

Autor: V V, Vlasov, E M, Ivanova, I V, Kutiavin, A S, Raĭt, L V, Iurchenko

Publikováno v: Molekuliarnaia biologiia. 23(1)

Interaction of alkylating deoxyribooligonucleotide derivatives, bearing 4-[(N-2-chloroethyl-N-methyl)amino]benzylamine residues at their 5'-terminal phosphates, with mouse fibroblasts L929 and with ascite carcinoma cells Krebs 2 has been investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7cd39c3d9003786dd7d7f0f527cef58
https://pubmed.ncbi.nlm.nih.gov/2739651

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