Zobrazeno 1 - 10
of 62
pro vyhledávání: '"I V, Hutchinson"'
Publikováno v:
Transplant Immunology. 5:122-128
Alloreactive T cells recognize either determinants of the intact donor MHC molecules displayed on the surface of transplanted-cells or peptide fragments of donor antigens associated with self-MHC molecules by means of their T cell receptors (TCR). To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d207d6e29402256122fc6ffd3f8e8aca
https://doi.org/10.1016/s0966-3274(97)80052-4
https://doi.org/10.1016/s0966-3274(97)80052-4
Publikováno v:
Eye. 9:155-160
Antibodies are known to damage grafted tissues by a variety of means, so it is important to know how the humoral response is initiated. In this paper we summarise the cellular events in B cell activation, the mechanisms of antibody-mediated rejection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41dcb6eaa88088849ff6b1a9edde8ff
https://doi.org/10.1038/eye.1995.32
https://doi.org/10.1038/eye.1995.32
Publikováno v:
Ciba Foundation Symposium 96 - Fetal Antigens and Cancer
The purpose of this study was to ascertain whether the protection afforded to adult mice against the induction and growth of 3-methylcholanthrene-induced tumours by prior exposure to syngeneic fetal cells has an immunological basis. Adult CBA mice we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9321e1aab50bbf3133697c52da30b14
https://doi.org/10.1002/9780470720776.ch8
https://doi.org/10.1002/9780470720776.ch8
Autor:
A H, Hajeer, I V, Hutchinson
Publikováno v:
Human immunology. 62(11)
Tumor necrosis factor alpha (TNFalpha) is a potent inflammatory cytokine. In human, the TNFalpha gene is located within the highly polymorphic major histocompatibility complex (MHC) region on chromosome 6p21.3. TNF gene cluster contains many polymorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57888c17acbd5a2af2270a74dac842f0
https://pubmed.ncbi.nlm.nih.gov/11704281
https://pubmed.ncbi.nlm.nih.gov/11704281
Publikováno v:
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 28(4)
We have identified a new single nucleotide polymorphism within the promoter region of the human allograft inflammatory factor (AIF-1) gene. The polymorphism, defined by Genbank accession number AF097515, was characterized as a C/T single base pair su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c24058101b1e3694cf54def78748924f
https://pubmed.ncbi.nlm.nih.gov/11532020
https://pubmed.ncbi.nlm.nih.gov/11532020
Autor:
M, Azzawi, P S, Hasleton, D M, Turner, N, Yonan, A K, Deiraniya, P J, Sinnott, I V, Hutchinson
Publikováno v:
Human immunology. 62(2)
Irreversible acute rejection of the transplanted heart usually has a fatal outcome. Predicting which recipients are most likely to reject might allow closer monitoring and modification of treatment protocols to prevent graft loss. Recipients genetica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b02f7953a4a5227dfa249b548e5dc2
https://pubmed.ncbi.nlm.nih.gov/11182223
https://pubmed.ncbi.nlm.nih.gov/11182223
Publikováno v:
Human immunology. 61(9)
We have described previously a variable length CA repeat sequence in the first intron of the human IFN-gamma gene and showed that allele #2 is associated with high in vitro IFN-gamma production. In a consecutive study, allele #2 was found to be assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e315187a60bb879e93ef2ae4c08e6033
https://pubmed.ncbi.nlm.nih.gov/11053629
https://pubmed.ncbi.nlm.nih.gov/11053629
Autor:
A H, Hajeer, I V, Hutchinson
Publikováno v:
Microscopy research and technique. 50(3)
TNF-alpha is a proinflammatory cytokine that has been implicated in the severity of different immune-regulated diseases including autoimmune diseases and transplantation. The gene for TNF-alpha is located within the MHC region on chromosome 6p21.3. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dff5d9f2b503904460c7a51f31adaf59
https://pubmed.ncbi.nlm.nih.gov/10891887
https://pubmed.ncbi.nlm.nih.gov/10891887
Autor:
W J, Burlingham, P J, O'Connell, L M, Jacobson, B N, Becker, A D, Kirk, V, Pravica, I V, Hutchinson
Publikováno v:
Transplantation. 69(7)
Genomic DNA was obtained from peripheral blood samples of patients JB and DS each of whom received a kidney transplant at 16 years of age from a serologically HLA-DR matched and HLA-class I -mismatched donor. Both patients discontinued immunosuppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86275474f249fd9de36a274074e65ea1
https://pubmed.ncbi.nlm.nih.gov/10798787
https://pubmed.ncbi.nlm.nih.gov/10798787
Publikováno v:
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 27(1)
We have described two rare, single-nucleotide polymorphisms within the promoter regions of the IL-12 p35 and p40 subunit genes. Transitions C to T at position -916 from the transcription start of the IL-12 p35 gene and G to T at position -1287 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de4153472084ee8dacdf492c3256198d
https://pubmed.ncbi.nlm.nih.gov/10651849
https://pubmed.ncbi.nlm.nih.gov/10651849