Zobrazeno 1 - 10
of 56
pro vyhledávání: '"I V, Gorudko"'
Autor:
M. S. Terekhova, I. V. Gorudko, D. V. Grigorieva, I. V. Semak, A. V. Sokolov, O. M. Panasenko, S. N. Cherenkevich
Publikováno v:
Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, Vol 0, Iss 7, Pp 80-84 (2019)
Lactoferrin (Lf) is a biologically important molecule, that accomplishes a number of useful functions in an organism. Lf can be situated in conditions associated with enrichment of reactive halogen species (asthma, infectious disease, heart-disease e
Externí odkaz:
https://doaj.org/article/ddab0bb6b2324921bcae696360d2bfe8
Autor:
A. V. Sokolov, V. A. Kostevich, N. V. Gorbunov, D. V. Grigorieva, I. V. Gorudko, V. B. Vasilyev, O. M. Panasenko
Publikováno v:
Медицинская иммунология, Vol 20, Iss 5, Pp 699-710 (2018)
Myeloperoxidase is a key factor promoting development of halogenative/oxidative stress under inflammatory conditions. Previously, we have discovered complexes including myeloperoxidase and its physiological inhibitor, ceruloplasmin in blood plasma of
Externí odkaz:
https://doaj.org/article/e627e47f30214d8aa883d46108f91c8a
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:467-490
Autor:
Oleg M. Panasenko, Daria V. Grigorieva, Alexander V. Timoshenko, N. A. Grudinina, Alexey V. Sokolov, I. V. Gorudko, Igor Semak
Publikováno v:
International Journal of Biological Macromolecules. 195:30-40
Previously we have shown that lactoferrin (LTF), a protein of secondary neutrophilic granules, can be efficiently modified by hypohalous acids (HOCl and HOBr), which are produced at high concentrations during inflammation and oxidative/halogenative s
Publikováno v:
System Biology and Physiology Reports. 1:3-11
In this study, we have revisited the existing and suggested new approaches to the use of patch-clamp methodology for measuring the activity of single ion channels and membrane potential of human platelets in the cell-attached configuration. We record
Autor:
Alexey V. Sokolov, I. V. Borodina, D. S. Matyushkina, Sergey N. Cherenkevich, Daria V. Grigorieva, I. V. Gorudko, Oleg M. Panasenko, V. E. Reut, V. A. Ivanov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:299-306
The interaction of the oxazine dye gallocyanine with reactive oxygen ( $$^{\centerdot }{\text{O}}_{2}^{ - },$$ Н2О2) and halogen (HOCl) species has been studied by spectrophotometry, mass spectrometry, and spectrofluorimetry. It has been shown that
Publikováno v:
Journal of Applied Spectroscopy. 87:693-700
We investigated the effect of drugs (dapsone, paracetamol, and isoniazid) on the production of reactive oxygen and halogen species by neutrophils. The standard fluorescent method using scopoletin as well as recently developed fluorescent methods usin
Publikováno v:
Biochemistry (Moscow). 85:34-55
This review discusses formation of reactive halogen species (RHS) catalyzed by myeloperoxidase (MPO), an enzyme mostly present in leukocytes. An imbalance between the RHS production and body’s ability to remove or neutralize them leads to the devel
Autor:
Nikolay N. Gorbunov, Valeria A. Kostevich, Veronika E. Lutsenko, Daria V. Grigorieva, Alexey V. Sokolov, Sergey N. Cherenkevich, I. V. Gorudko, Oleg M. Panasenko
Publikováno v:
Medical academic journal. 19:63-71
Objective — the study of hypochlorous acid (HOCl) and its derivatives production, which catalyzed by human neutrophil myeloperoxidase, using “turn-on” fluorescent sensor — celestine blue B. Materials and methods. Neutrophils were isolated fro
Publikováno v:
Medical academic journal. 18:58-63
This work showed for the first time that recombinant lactoferrin isolated from the milk of transgenic goats binds to the plasma membrane of platelets. The interaction of recombinant lactoferrin with platelets leads to the potentiation or inhibition o