Výsledky vyhledávání - "I V, Ekimova"

Akademický článek

Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures I. V. Ekimova et al. Exo-Hsp70/Hsc70 in chemically-induced seizures.

Autor: Ekimova, Irina V.¹, Nitsinskaya, Larisa E.¹, Romanova, Irina V.², Pastukhov, Yuri F.¹, Margulis, Boris A.³, Guzhova, Irina V.³ guzhova@mail.cytspb.rssi.ru

Publikováno v: Journal of Neurochemistry. Nov2010, Vol. 115 Issue 4, p1035-1044. 10p. 3 Color Photographs, 1 Graph.

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The Chaperone Inducer U133 Eliminates Anhedonia and Prevents Neurodegeneration in Monoaminergic Emotiogenic Brain Structures in a Preclinical Model of Parkinson’s Disease in Aged Rats

Autor: Yu. F. Pastukhov, S. G. Polonik, D. V. Belan, I. V. Ekimova, M. B. Pazi

Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 57:1130-1141

Parkinson’s disease (PD) is a neurodegenerative disorder mainly diagnosed in elderly patients, which is now considered incurable. To date, there are no effective neuroprotectors suitable to treat PD patients. We have previously demonstrated that U1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fff162c506bd1896e01bcbe1699c3803
https://doi.org/10.1134/s0022093021050148

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Preventive Administration of the Heat Shock Protein Hsp70 Relieves Endotoxemia-Induced Febrile Reaction in Pigeons (Columba livia) and Rats

Autor: Irina V. Guzhova, K. V. Lapshina, I. V. Ekimova

Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 57:1060-1071

The stress-inducible 70 kDa heat shock protein (Hsp70) can exert a protective effect on endotoxemia and sepsis due to its ability to interact with immune cells and modulate the immune response. However, it remains unknown whether Hsp70 is able to rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd55170091420a0bda5c09485b09ad1b
https://doi.org/10.1134/s0022093021050082

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Autor: Yu. F. Pastukhov, I. V. Ekimova, V. V. Simonova, M. A. Guzeev

Publikováno v: Neuroscience and Behavioral Physiology. 51:704-710

Objective. To assess changes in the time characteristics of the states of sleep and waking which may serve as nonmotor signs of the initial stage of PD using a model of the preclinical stage of Parkinson’s disease (BP) in Wistar rats of different a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6361156ee1b91670367d9bd1a4e32b10
https://doi.org/10.1007/s11055-021-01124-z

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Assessment of the Efficacy of Preventive Therapy with Chaperone Inducer U133 in a Model of the Preclinical Stage of Parkinson’s Disease in Elderly Rats

Autor: S. G. Polonik, D. V. Belan, I. V. Ekimova

Publikováno v: Neuroscience and Behavioral Physiology. 51:673-680

Parkinson’s disease (PD) is a chronic relentlessly progressive neurodegenerative disease mainly affecting dopamine (DA)-ergic neurons in the nigrostriatal system of the brain. PD mostly affects elderly people and is incurable. Impairments to the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b46dce28250af77ed99a046084ba029b
https://doi.org/10.1007/s11055-021-01120-3

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U-133, a Chaperone Inducer, Eliminates Sleep Disturbances in a Model of the Preclinical Stage of Parkinson’s Disease in Aged Rats

Autor: T. S. Shemyakova, I. V. Ekimova, V. V. Simonova, S. G. Polonik, Yu. F. Pastukhov, M. A. Guzeev

Publikováno v: Advances in Gerontology. 10:254-259

Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease that is closely associated with aging. It is considered incurable due to its late diagnosis and the use of symptomatic treatment, which cannot alter the molecular mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::faaaf93eaeae4f49ba93b2dc4e9aa719
https://doi.org/10.1134/s2079057020030133

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Impairment to Cognitive Functions in Wistar Rats in a Model of the Preclinical Stage of Parkinson’s Disease

Autor: Yu. F. Pastukhov, I. V. Ekimova, M. V. Chernyshev, A. V. Matsulevich, N. N. Abdurasulova

Publikováno v: Neuroscience and Behavioral Physiology. 50:439-450

The preclinical stage of Parkinson’s disease (PD), when most dopaminergic neurons in the nigrostriatal system of the brain are still intact and compensatory mechanisms have not yet been overwhelmed, is the most effective “therapeutic window.” M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9c8e00f34f1210842fcd49dfb7d6d84
https://doi.org/10.1007/s11055-020-00919-w

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Assessment of the Neuroprotective Potential of Glucose-Regulated Heat Shock Protein in a Model of Parkinson’s Disease in Rats

Autor: I. V. Ekimova, M. B. Pazi, D. V. Plaksina

Publikováno v: Neuroscience and Behavioral Physiology. 50:119-125

Parkinson’s disease (PD) is a multisystem chronic progressive neurodegenerative disease which to date is among the untreatable neurodegenerative diseases. Progress in treatment is linked with the development of new techniques for prophylactic neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd72420cb4fa28fa3a7c56c62153039d
https://doi.org/10.1007/s11055-019-00877-y

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