Výsledky vyhledávání - "I V, Alexeeva"

Сationic carboxamide derivatives of tricyclic heteroaromatic compounds: synthesis and preliminary evaluation of antiproliferative activity

Autor: I. V. Alexeeva, N. A. Lysenko, V. V. Negrutska, V. G. Kostina, Igor Dubey

Publikováno v: Ukr. Bioorg. Acta 2020, Vol. 15, N1. 15:34-41

This research was aimed at the synthesis and study of biological activity of the carboxamides of tricyclic heteroaromatic systems, acridone, phenazine and thioxanthone, containing the aliphatic and aromatic cationic substituents at amide fragment. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::467237ace1423cc6f01ec76f207546ec
https://doi.org/10.15407/bioorganica2020.01.034

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The Polarimetry of Нα-prominences

Autor: E. Z. Suyunova, A. R. Osokin, V. V. Popov, I. V. Mironova, I. V. Alexeeva, I. S. Kim

Publikováno v: Geomagnetism and Aeronomy. 58:1073-1080

A brief comparative analysis determining the magnetic field in optical and radio range prominences is presented; a tendency to increase averaged magnetic fields two to four times in quiescent and active prominences, compared to previously accepted va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2ae527389e78085f3c5ecfa885f1878
https://doi.org/10.1134/s0016793218080091

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Telomerase inhibition by new di- and trisubstituted acridine derivatives

Autor: N. A. Lysenko, I. V. Saraieva, I. Ya. Dubey, I. V. Alexeeva, V. G. Kostina, V. V. Negrutska

Publikováno v: Biopolymers and Cell, Vol 32, Iss 6, Pp 468-471 (2016)

Aim. To study a series of new acridine derivatives containing two basic fragments able to bind to quadruplex DNA at C-4 and C-9 positions as potential telomerase inhibitors. Methods. TRAP assay was used to determine the activity of compounds in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac62c1238cdb7febc8328e569cc44231
https://doi.org/10.7124/bc.00093e

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New 1,2,4-triazine bearing compounds: molecular modeling, synthesis and biotesting

Autor: A. D. Shved, L. S. Usenko, M. O. Platonov, O. M. Kostenko, V. V. Negrutska, I. V. Alexeeva, L. G. Palchykovska

Publikováno v: Biopolymers and Cell, Vol 25, Iss 6, Pp 491-499 (2009)
Scopus-Elsevier

Aim. To enlarge a spectrum of biologically active compounds in the series of the 1,2,4-triazino[5,6-b] [1,4]benzothiazine (1,2,4-TBT) derivatives and reveal among them efficient inhibitors of RNA synthesis Methods. The methods of structure optimizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab37b0aa45fe538c6c732c6340ad887d
http://www.biopolymers.org.ua/archive/2009/06/ru/Palchikovskaya.pdf

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New acridone-4-carboxylic acid derivatives as potential inhibitors of Hepatitis C virus infection

Autor: Anna Stankiewicz-Drogoń, Larisa G. Palchykovska, Anna M. Boguszewska-Chachulska, V. G. Kostina, I. V. Alexeeva, A. D. Shved

Publikováno v: Bioorganic & Medicinal Chemistry. 16:8846-8852

A new class of compounds—acridone derivatives—was tested using the direct fluorometric helicase activity assay to determine the inhibitory properties of the derivatives towards the NS3 helicase of Hepatitis C virus (HCV). The compounds were also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fa2bcf2a33fd1cc58c7f7a17afed3b
https://doi.org/10.1016/j.bmc.2008.08.074

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Tricyclic 1,2,4-triazine bearing heterosystem: directed synthesis of new bioactive compounds

Autor: V. G. Kostina, L. S. Usenko, L. G. Palchikovs'ka, I. V. Alexeeva

Publikováno v: Biopolymers and Cell. 24:406-411

A new se ries of tricyclic heteroaromatic com pounds was pre pared by cyclization of N2-sub sti tuted-6-bromo-3-oxo(amino)-1,2,4-tri azin-5(4I)-ones with 2-aminobenzothiol. The struc ture of bioactive tricyclic glycosides, ob tained ear lier by the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::978fac7ae2b1abb1c1c7d7ae6f4f8981
https://doi.org/10.7124/bc.0007b9

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