Zobrazeno 1 - 10
of 23
pro vyhledávání: '"I S Figari"'
Publikováno v:
The Journal of Immunology. 151:4637-4641
TNF-alpha can enhance the proliferation of human thymocytes stimulated by the comitogen Con A. To determine which of the two different TNF receptors is responsible for signaling this cellular response, we investigated the proliferation of human thymo
Autor:
I S Figari, Michael A. Palladino
Publikováno v:
Annals of the New York Academy of Sciences. 685:483-487
Autor:
Scot A. Marsters, Avi Ashkenazi, Steven M. Chamow, Douglas H. Smith, Daniel J. Capon, I S Figari, Diane Pennica, David V. Goeddel, Michael A. Palladino
Publikováno v:
Proceedings of the National Academy of Sciences. 88:10535-10539
Tumor necrosis factors (TNF) alpha and beta are structurally related cytokines that mediate a wide range of immunological, inflammatory, and cytotoxic effects. During bacterial infection of the bloodstream (sepsis), TNF-alpha induction by bacterial e
Publikováno v:
The Journal of Experimental Medicine
Using recombinant DNA technology, we have generated Chinese hamster ovary (CHO) cell lines that synthesize latent transforming growth factor beta 1 (TGF-beta 1) to study immune regulation by TGF-beta 1. In vitro, latent TGF-beta 1 synthesized by tran
Publikováno v:
Novartis Foundation Symposia ISBN: 9780470513521
Ciba Foundation Symposium 131-Tumour Necrosis Factor and Related Cytotoxins
Ciba Foundation Symposium 131-Tumour Necrosis Factor and Related Cytotoxins
The discoveries of a tumour necrosis-inducing substance in sera of experimental mice and of cytotoxic factor(s) in cultures of stimulated lymphoid cells triggered intense research efforts which have culminated in the production of two distinct but re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2783ca0f60b8c8e2988b19e921f3cdd
https://doi.org/10.1002/9780470513521.ch3
https://doi.org/10.1002/9780470513521.ch3
Publikováno v:
Ciba Foundation Symposium 157-Clinical Applications of TGF-β
TGF-beta is a potent regulator of immune functions both in vitro and in vivo. The majority of studies have examined changes in immune functions after the addition of TGF-beta that had been previously activated by acid treatment. Peripheral blood mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c7b9c3206ae566de78f9195b17e17a0
https://doi.org/10.1002/9780470514061.ch7
https://doi.org/10.1002/9780470514061.ch7
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461360384
The protooncogene, HER2 (also known as c-erbB-2, neu, and HER-2 / neu) encodes a receptor tyrosine kinase, p185HER2 which is homologous to the EGF receptor (EGFr). HER2 was found to be amplified from 2 to 20-fold in up to ~ 30% of primary human breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e14aa9cb6188d01cb1b6dee551b09f1
https://doi.org/10.1007/978-1-4615-2443-4_9
https://doi.org/10.1007/978-1-4615-2443-4_9
Autor:
L A, Tartaglia, D V, Goeddel, C, Reynolds, I S, Figari, R F, Weber, B M, Fendly, M A, Palladino
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(9)
TNF-alpha can enhance the proliferation of human thymocytes stimulated by the comitogen Con A. To determine which of the two different TNF receptors is responsible for signaling this cellular response, we investigated the proliferation of human thymo
Autor:
Wai Lee Wong, I S Figari, H M Shepard, Brian M. Fendly, Paul Carter, Cornelia M. Gorman, Gail D. Lewis
Publikováno v:
Cancer immunology, immunotherapy : CII. 37(4)
The HER2 protooncogene encodes a receptor tyrosine kinase, p185HER2. The overexpression of p185HER2 has been associated with a worsened prognosis in certain human cancers. In the present work we have screened a variety of different tumor cell lines f
Autor:
Dyana K. Dalton, Sharon Pitts-Meek, I S Figari, Allan Bradley, Timothy A. Stewart, Satish Keshav
Publikováno v:
Science (New York, N.Y.). 259(5102)
Interferon-gamma (IFN-gamma) is a pleiotrophic cytokine with immunomodulatory effects on a variety of immune cells. Mice with a targeted disruption of the IFN-gamma gene were generated. These mice developed normally and were healthy in the absence of