Zobrazeno 1 - 10
of 33
pro vyhledávání: '"I S, Stafeev"'
Autor:
I. S. Stafeev, A. D. Yudaeva, S. S. Michurina, M. Yu. Menshikov, M. V. Shestakova, Y. V. Parfyonova
Publikováno v:
Сахарный диабет, Vol 26, Iss 2, Pp 192-202 (2023)
In the modern world the prevalence of obesity and type 2 diabetes mellitus (T2DM) significantly increases. In this light the risks of obesity-associated complications also grow up. The crucial linkage between obesity and its complications is inflamma
Externí odkaz:
https://doaj.org/article/3a916937eb8e4adfb13a5534f48bd750
Autor:
A. D. Yudaeva, I. S. Stafeev, S. S. Michurina, M. Yu. Menshikov, M. V. Shestakova, Y. V. Parfyonova
Publikováno v:
Сахарный диабет, Vol 26, Iss 1, Pp 75-81 (2023)
In the modern world the prevalence of obesity and type 2 diabetes mellitus (T2DM) significantly increases. In this light the risks of obesity-associated complications also grow up. The crucial linkage between obesity and its metabolic and cardiovascu
Externí odkaz:
https://doaj.org/article/6cb8f36c442f445096606d039c77de70
Publikováno v:
Mitochondrion. 59:157-168
Non-shivering thermogenesis takes place in brown and beige adipocytes and facilitates cold tolerance and acclimation. However, thermogenesis in adipose tissue also was found to be activated in metabolic overload states for fast utilization of nutrien
Publikováno v:
International Journal of Endocrinology, Vol 2017 (2017)
Obesity is a growing problem in modern society and medicine. It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myo
Externí odkaz:
https://doaj.org/article/b01dbd9422c042cf9ad58029c49c616c
Autor:
K. V. Dergilev, M. Yu. Men’shikov, I. B. Beloglazova, E. V. Parfyonova, I. S. Stafeev, E. S. Zubkova, E. I. Ratner
Publikováno v:
Bulletin of Experimental Biology and Medicine. 167:492-495
TNFα mediates the expression of MMP-9 in THP-1 monocytes induced by urokinase (uPA). Upregulation of MMP-9 caused by uPA and TNFα is suppressed by etanercept, a TNFα inhibitor. In addition, uPA stimulates TNFα mRNA expression. Both uPA and TNFα
Autor:
N. Podkuychenko, S. Michurina, Ye. V. Parfyonova, I. S. Stafeev, Mikhail Menshikov, Alexander V. Vorotnikov
Publikováno v:
Biochemistry (Moscow). 84:553-561
Obesity is accompanied by dyslipidemia, hypoxia, endoplasmic reticulum (ER) stress, and inflammation, representing the major risk factor for the development of insulin resistance (IR) and type 2 diabetes. We modeled these conditions in cultured 3T3-L
Autor:
S. Michurina, E. I. Ratner, Ekaterina A. Shestakova, N. Podkuychenko, Ye. V. Parfyonova, I. S. Stafeev, A. Panevina, Yuriy Ivanovich Yashkov, Marina Vladimirovna Shestakova, Mikhail Menshikov, V. Fedenko, Igor A. Sklyanik, Alexander V. Vorotnikov, Kamil Yahyaev
Publikováno v:
Journal of Diabetes and its Complications. 33:148-159
Background Obesity and type 2 diabetes mellitus (T2DM) are among the most important morbidity factors. In this study we tested the hypothesis that low proliferative potential of adipose derived stromal cells (ADSC) associates with reduced formation o
Autor:
N. Podkuychenko, Marina Vladimirovna Shestakova, Asker Y. Khapchaev, Alexander V. Vorotnikov, Maxim Skulachev, Vladimir P. Shirinsky, Tatiana Vlasik, Vadim Z. Lankin, I. S. Stafeev, Mikhail V. Samsonov
Publikováno v:
Diabetes. 70
In diabetes-associated hyperlipidemia, free fatty acids (FFAs) are thought to induce insulin resistance and endothelial dysfunction leading to vascular injury and cardiovascular T2DM complications. However, evidence is scarce regarding the effects of
Autor:
N. Podkuychenko, Asker Y. Khapchaev, Alexander V. Vorotnikov, I. S. Stafeev, Vladimir P. Shirinsky, S. Michurina
Publikováno v:
Diabetes. 70
Increased levels of circulating free fatty acids (FFA) is the major risk factor for type 2 diabetes in obesity. While the long-term effects of increased FFA on adipose tissue likely involve latent inflammation, the short-term effects on insulin-sensi
Autor:
E. I. Ratner, Anatoliy Yurasov, Yelena V. Parfyonova, Marina Vladimirovna Shestakova, Ekaterina A. Shestakova, I. S. Stafeev, Kamil Yahyaev, Mikhail Menshikov, Igor A. Sklyanik, Alexander V. Vorotnikov, S. Michurina, E. Mamontova
Publikováno v:
Diabetes. 70
Objective: We have performed the comparative study of basal state of SGK-dependent signaling among obese patients with/without type 2 diabetes mellitus (T2DM). We have accomplished correlation analysis of glucose metabolism and incretin profile param