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pro vyhledávání: '"I S, Ayene"'
Publikováno v:
Radiation research. 146(5)
Most in vitro studies of the modification of radiation damage to DNA by oxygen and reduced thiol compounds have excluded non-thiol .OH scavengers. However, the non-thiol .OH scavengers are known to be very effective radiation protectors and are prese
Publikováno v:
Radiation research. 144(1)
A number of investigations have suggested that the widely observed oxygen enhancement of radiation-induced cell killing or intracellular DNA damage requires the presence of glutathione (GSH) or other thiols. We have adapted an in vitro model system t
Publikováno v:
Radiation research. 142(2)
Studies of intact cells have generally shown a substantial enhancement by oxygen of radiation-induced cell killing or DNA breakage, with an oxygen enhancement ratio (OER) of 2.5-3. Analogous studies of radiation damage to purified DNA in aqueous solu