Zobrazeno 1 - 10
of 20
pro vyhledávání: '"I Richard Thompson"'
Autor:
Yi-Ting Tsai, Nogayhan Seymen, I Richard Thompson, Xinchen Zou, Warisha Mumtaz, Sila Gerlevik, Ghulam J Mufti, Mohammad M Karimi
Publikováno v:
eLife, Vol 13 (2024)
Retrotransposons (RTEs) have been postulated to reactivate with age and contribute to aging through activated innate immune response and inflammation. Here, we analyzed the relationship between RTE expression and aging using published transcriptomic
Externí odkaz:
https://doaj.org/article/1bd4e5dc38914a7780624f5ed7854f4f
Autor:
Sila Gerlevik, Nogayhan Seymen, Shan Hama, Warisha Mumtaz, I Richard Thompson, Seyed R Jalili, Deniz E Kaya, Alfredo Iacoangeli, Andrea Pellagatti, Jacqueline Boultwood, Giorgio Napolitani, Ghulam J Mufti, Mohammad M Karimi
Publikováno v:
eLife, Vol 13 (2024)
Mutational profiles of myelodysplastic syndromes (MDS) have established that a relatively small number of genetic aberrations, including SF3B1 and SRSF2 spliceosome mutations, lead to specific phenotypes and prognostic subgrouping. We performed a mul
Externí odkaz:
https://doaj.org/article/3ee4a561cd2144888814648747b54fd4
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182059 (2017)
Stress Granules (SGs) are dynamic ribonucleoprotein aggregates, which have been observed in cells subjected to environmental stresses, such as oxidative stress and heat shock (HS). Although pluripotent stem cells (PSCs) are highly sensitive to oxidat
Externí odkaz:
https://doaj.org/article/b499ee93c1c7457d854e8f526a8b59ea
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
It is now evident that DNA forms an organized nuclear architecture, which is essential to maintain the structural and functional integrity of the genome. Chromatin organization can be systematically studied due to the recent boom in chromosome confor
Externí odkaz:
https://doaj.org/article/d1ad71cf7669483b8d1d39704bb01462
Publikováno v:
Cells, Vol 11, Iss 23, p 3833 (2022)
Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem cells. However, this process
Externí odkaz:
https://doaj.org/article/39c4c427f4f94eb58e7f671008663588
Autor:
Salam Salloum-Asfar, Rudolf Engelke, Hanaa Mousa, Neha Goswami, I. Richard Thompson, Freshteh Palangi, Kamal Kamal, Muna N. Al-Noubi, Frank Schmidt, Sara A. Abdulla, Mohamed M. Emara
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates that different types of ce
Externí odkaz:
https://doaj.org/article/1205d84d15c8408f8cc7c6e129328464
Autor:
Kamal Kamal, I. Richard Thompson, Rudolf Engelke, Neha Goswami, Mohamed Emara, Sara A. Abdulla, Muna N. Al-Noubi, Freshteh Palangi, Frank Schmidt, Salam Salloum-Asfar, Hanaa Mousa
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2021 (2021)
Stem Cells International, Vol 2021 (2021)
Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates that different types of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7de8343751871203e087abc267ba43
https://doi.org/10.1155/2021/8274936
https://doi.org/10.1155/2021/8274936
Autor:
I. Richard Thompson, Elmoubasher Farag, Hadi M. Yassine, Hebah A. Al Khatib, Peter Coyle, Asmaa A. Al Thani, Muna Al Maslamani
Publikováno v:
Microorganisms, Vol 8, Iss 1, p 133 (2020)
Microorganisms
Volume 8
Issue 1
Microorganisms
Volume 8
Issue 1
The diversity of RNA viruses dictates their evolution in a particular host, community or environment. Here, we reported within- and between-host pH1N1virus diversity at consensus and sub-consensus levels over a three-year period (2015&ndash
2017
2017
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a226aee00d1981d8d88ff0e4f795eee6
https://www.mdpi.com/2076-2607/8/1/133
https://www.mdpi.com/2076-2607/8/1/133
Publikováno v:
Meta Gene. 13:57-62
Intellectual disability (ID) is a common heterogeneous disease. Many genes have been implicated in the etiology of ID, yet gene discovery continues at a fast pace. In this study, we investigated the genetic cause of ID in a consanguineous Arab family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff93713bbcd5102d15a7e1d22614cad
https://doi.org/10.1016/j.mgene.2017.05.002
https://doi.org/10.1016/j.mgene.2017.05.002
Autor:
Mohamed Emara, Chris R. Triggle, Freshteh Palangi, Samson Mathews Samuel, I. Richard Thompson
Publikováno v:
Qatar Foundation Annual Research Conference Proceedings Volume 2018 Issue 2.
In cells subjected to environmental stresses, such as oxidative stress and heat shock (HS), dynamic ribonucleoprotein aggregates, known as Stress Granules (SGs)), are formed as a part of the cell response program. Different types of stresses control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0827381e1f2f805e0fc3c1b5d37a4904
https://doi.org/10.5339/qfarc.2018.hbpp822
https://doi.org/10.5339/qfarc.2018.hbpp822