Zobrazeno 1 - 10
of 70
pro vyhledávání: '"I R Peake"'
Autor:
D. Ginsburg, P. M. Mannucci, L. Vermylen, M. Blombäck, C Petersson, I. R. Peake, J. J. Michiels, Stefan Lethagen, R. Nuss, Christian Freiburghaus, Lilian Tengborn, Rolf Ljung, F. Giannelli, C. Rodriguez-Merchan, Björn Dahlbäck, Erik Berntorp, L. Hoyer, Lars Holmberg, Jan Astermark, L. Aledort, H. Petersson, G. Mariani
Publikováno v:
Haemophilia. 7:401-410
Professor Inga Marie Nilsson (1923-99) was a pioneer in the field of bleeding and thrombo-embolic disorders and made several major scientific contributions during her career. To honour her memory, colleagues from all over the world were invited to co
Publikováno v:
Blood. 88:1700-1707
The molecular basis of type I or III Protein S deficiency has been investigated in three kindred also showing independent inheritance of factor V (FV) Leiden. A T to C transition in codon 570 (Met-->Thr) was identified in the propositi and shown to s
Publikováno v:
Blood. 77:1476-1483
Recent reports of the mutations resulting in von Willebrand disease (vWD) have indicated that some cases of type IIA vWD are caused by single nucleotide substitutions in the gene encoding von Willebrand factor (vWF). However, the molecular pathogenes
Autor:
EA Tuley, CL Verweij, JM Sorace, I. R. Peake, M. B. Liddell, DJ Mancuso, P Moodie, LA Westfield, G Standen, J E Sadler
Publikováno v:
Blood. 75:654-661
Southern blotting was performed with cDNA probes for the human von Willebrand factor (vWF) gene on six patients with severe type III von Willebrand's disease (vWD). A partial deletion in the 3′ end of the vWF gene was demonstrated in one individual
Publikováno v:
British journal of haematology. 124(6)
Publikováno v:
British journal of haematology. 113(4)
Publikováno v:
British journal of haematology. 113(4)
Genomic DNA from 97 cases of adult de novo acute myeloid leukaemia (AML) was screened using polymerase chain reaction (PCR) and conformation-sensitive gel electrophoresis (CSGE) for FLT3 exon 20 mutations. Initial sequencing of four cases, representi
Autor:
A C, Goodeve, J C, Eikenboom, D, Ginsburg, L, Hilbert, C, Mazurier, I R, Peake, J E, Sadler, F, Rodeghiero
Publikováno v:
Thrombosis and haemostasis. 85(5)
Examination of the entire von Willebrand factor (VWF) gene for mutations, particularly in types 1 and 3 von Willebrand disease (VWD) is becoming more widely practised. The sequence of the entire VWF gene will soon be compiled as a single sequence. Fo
Publikováno v:
Thrombosis and haemostasis. 83(5)
The molecular basis of quantitative antithrombin deficiency was investigated in four families predicted to have major antithrombin gene rearrangements. A 1,442 bp deletion and insertion of the sequence 5'T(n = 38-40)GAGACG was characterised in one ca
Autor:
M, Makris, M, Leach, N J, Beauchamp, M E, Daly, P C, Cooper, K K, Hampton, P, Bayliss, I R, Peake, G J, Miller, F E, Preston
Publikováno v:
Blood. 95(6)
Protein S deficiency is a recognized risk factor for venous thrombosis. Of all the inherited thrombophilic conditions, it remains the most difficult to diagnose because of phenotypic variability, which can lead to inconclusive results. We have overco