Zobrazeno 1 - 10
of 25
pro vyhledávání: '"I R, Macgregor"'
Publikováno v:
Scopus-Elsevier
Pulmonary microvascular injury, one of the earliest events in adult respiratory distress syndrome (ARDS), is caused by the release of injurious products from stimulated neutrophils and other inflammatory cells in the lung microvessels. An increased l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646fa417adfee2985fc1af318d7da349
https://doi.org/10.1164/ajrccm.155.1.9001288
https://doi.org/10.1164/ajrccm.155.1.9001288
Publikováno v:
Vox sanguinis. 93(2)
The DiaMed Impact R tests platelet function under close to physiological flow conditions using cone and plate technology. An image analyser quantifies the adhered platelets and results are expressed as percentage of well surface covered by aggregates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ccbc1fd447a4bd95f6f25bf16500181
https://pubmed.ncbi.nlm.nih.gov/17683361
https://pubmed.ncbi.nlm.nih.gov/17683361
Autor:
H E, Reichl, P R, Foster, A G, Welch, Q, Li, I R, MacGregor, R A, Somerville, K, Fernie, P J, Steele, D M, Taylor
Publikováno v:
Vox sanguinis. 83(2)
There is still uncertainty over how the agent of variant Creutzfeld-Jakob disease (vCJD) would partition during the manufacture of plasma derivatives. In this study, a BSE-derived agent was used as a vCJD model to determine the extent to which infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd73280a96b09f87aea3e0571fe44710
https://pubmed.ncbi.nlm.nih.gov/12201843
https://pubmed.ncbi.nlm.nih.gov/12201843
Autor:
I R, MacGregor, O, Drummond
Publikováno v:
Vox sanguinis. 81(4)
The concern that variant Creutzfeldt-Jakob disease could be transmitted via blood transfusion has prompted studies of blood infectivity in animal models. As normal prion protein acts as a substrate for conversion to the abnormal form associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c33184db0dfd13d7a496ecdb4cbec0e8
https://pubmed.ncbi.nlm.nih.gov/11903999
https://pubmed.ncbi.nlm.nih.gov/11903999
Autor:
C V, Prowse, V S, Hornsey, O, Drummond, I R, MacGregor, D S, Pepper, G R, Barclay, H, Bethel, B, Walker, G, Barnard, L, Kirby, J, Hope
Publikováno v:
British journal of haematology. 106(1)
Universal leucodepletion is being introduced in the U.K. to reduce a theoretical risk of Creutzfeldt-Jakob disease (CJD) transmission. If CJD infectivity is associated with leucocytes, any cell fragmentation associated with filtration could reduce th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fede322493b6e9873e3e7bfbc13f03fb
https://pubmed.ncbi.nlm.nih.gov/10444194
https://pubmed.ncbi.nlm.nih.gov/10444194
Autor:
K. Little, Colin Robertson, D. J. Steedman, M. W. G. Gordon, I R MacGregor, Seamas C. Donnelly, Christopher Haslett, Adil Zamani
Publikováno v:
Scopus-Elsevier
Inflammatory cells, particularly neutrophil granulocytes, have been implicated in the pathogenesis of the adult respiratory distress syndrome (ARDS). In this study, we investigated whether a relationship exists between neutrophil elastase in the plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adee31802083b5d95af332af27be4d76
https://pubmed.ncbi.nlm.nih.gov/7735596
https://pubmed.ncbi.nlm.nih.gov/7735596
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 5(3)
Some well-described similarities exist between tissue plasminogen activator (t-PA) and von Willebrand factor (vWf) which may suggest a link in either the synthesis or release of both proteins from endothelial cells. To investigate this relationship f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ec553c7dab63594724e139edc73d469
https://pubmed.ncbi.nlm.nih.gov/8075304
https://pubmed.ncbi.nlm.nih.gov/8075304
Autor:
R. A. Riemersma, I. R. MacGregor, N. A. Boon, A. M. Perrie, F. Stenhouse, K. G. M. M. Alberti, Robert A. Wright
Publikováno v:
European journal of clinical pharmacology. 46(3)
This double-blind, randomized parallel group study investigated the effect of 6 months beta-adrenoceptor antagonist therapy with either metoprolol (beta 1-selective without intrinsic sympathomimetic activity [ISA]) or epanolol (beta 1-selective with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8cf14637b0891b46488848b0fad9dc
https://pubmed.ncbi.nlm.nih.gov/7915237
https://pubmed.ncbi.nlm.nih.gov/7915237
Publikováno v:
Thrombosis and haemostasis. 68(5)
A non-stasis rodent model of thrombogenicity has been used for dose-ranging studies with a conventional prothrombin complex concentrate (PCC) and to evaluate high purity factor IX concentrates from different manufacturers. Fibrin monomer (soluble fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6c6512e384201ea7c764ba156fc147d
https://pubmed.ncbi.nlm.nih.gov/1455396
https://pubmed.ncbi.nlm.nih.gov/1455396
Publikováno v:
Thrombosis and haemostasis. 66(5)
A non-stasis canine model of thrombogenicity has been used to evaluate batches of high purity factor IX concentrates from 4 manufacturers and a conventional prothrombin complex concentrate (PCC). Platelets, activated partial thromboplastin time (APTT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a34480ad08b79d30c3940b9a3643c34
https://pubmed.ncbi.nlm.nih.gov/1803625
https://pubmed.ncbi.nlm.nih.gov/1803625