Zobrazeno 1 - 5
of 5
pro vyhledávání: '"I P, Baĭkova"'
Publikováno v:
Терапевтический архив, Vol 85, Iss 2, Pp 76-84 (2013)
The given clinical review covers current antiviral therapy for chronic hepatitis C. Traditional antiviral therapy with pegylated interferon-α and ribavirin in patients with chronic hepatitis C virus genotype 1 allows a sustained virological response
Externí odkaz:
https://doaj.org/article/e4015e0defd84f258a5be94479ea0ffe
Publikováno v:
Терапевтический архив, Vol 84, Iss 11, Pp 75-80 (2012)
The review considers the chemical structure, pharmacodynamics and pharmacokinetics of telaprevir, a new direct-acting antiviral agent, used to treat patients with chronic hepatitis C (CHC). The given data on Phase II and III clinical trials enable th
Externí odkaz:
https://doaj.org/article/649ab5e503c14da29dde9dfb96d78825
Publikováno v:
Bioorganicheskaia khimiia. 37(3)
The synthesis of aminopropoxy derivatives of betulin, erythrodiol, uvaol and oleantriol via cyanoethylation of triterpenoids hydroxyl groups and subsequent reduction of cyanoethyl fragments is described. High and specific in vitro antitumor activity
Autor:
O B, Kazakova, N I, Medvedeva, I P, Baĭkova, G A, Tolstikov, T V, Lopatina, M S, Iunusov, L, Zaprutko
Publikováno v:
Bioorganicheskaia khimiia. 36(6)
The synthesis of a new group of triterpenoid acylates on the basis of oleanolic, glycyrrhetic and ursolic acids and betulin is described. In studying the activity of the synthesized compounds in relation to reproduction of virus pathogens of respirat
Autor:
O B, Flekhter, L T, Karachurina, V V, Poroĭkov, L R, Nigmatullina, L A, Baltina, F S, Zarudiĭ, V A, Davydova, L V, Spirikhin, I P, Baĭkova, F Z, Galin, G A, Tolstikov
Publikováno v:
Bioorganicheskaia khimiia. 26(3)
Hemisuccinates, hemiphthalates, acetylsalicylates, cinnamates, and p-methoxycinnamates of lupeol, betulin, and 3-O-acetylbetulin were synthesized via interaction with corresponding acid anhydrides or acid chlorides. A number of betulin esters in posi