Zobrazeno 1 - 10
of 47
pro vyhledávání: '"I O, Petruseva"'
Autor:
I. O. Petruseva, Konstantin N. Naumenko, Aleksei A. Popov, Aleksei N. Evdokimov, Olga I. Lavrik, Konstantin E. Orishchenko
Publikováno v:
Acta Naturae. 13:122-125
The nucleotide excision repair (NER) is one of the main repair systems present in the cells of living organisms. It is responsible for the removal of a wide range of bulky DNA lesions. We succeeded in developing a method for assessing the efficiency
Autor:
Elena I. Ryabchikova, Inna N. Lavrik, Alexei Evdokimov, Olga I. Lavrik, Svetlana A. Romanenko, I. O. Petruseva, Vladimir A. Trifonov, Olga A. Koval, A. V. Popov
Publikováno v:
Aging (Albany NY)
The naked mole rat (NMR), Heterocephalus glaber, is the longest-living rodent species, and is extraordinarily resistant to cancer and aging-related diseases. The molecular basis for these unique phenotypic traits of the NMR is under extensive researc
Autor:
Olga I. Lavrik, Jochen Kuper, Rashid O. Anarbaev, Jeannette Kappenberger, I. O. Petruseva, Caroline Kisker, Natalia Naumenko
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The successful elimination of bulky DNA damages via the nucleotide excision repair (NER) system is largely determined by the damage recognition step. This step consists of primary recognition and verification of the damage. The TFIIH helicase XPD pla
Publikováno v:
Acta Naturae
The nucleotide excision repair (NER) is one of the main repair systems present in the cells of living organisms. It is responsible for the removal of a wide range of bulky DNA lesions. We succeeded in developing a method for assessing the efficiency
Publikováno v:
BIO Web of Conferences, Vol 22, p 01017 (2020)
Naked mole rat is the long-lived and tumor-resistant rodent. Naked mole rat possesses multiple adaptations that may contribute to longevity and cancer-resistance. Higher activity of DNA excision repair systems and their faster recovery after genotoxi
Publikováno v:
Molecular Biology. 52:237-246
Model DNA molecules that contain bulky lesions in both strands have been created, and their properties as substrates of the nucleotide excision repair (NER) system have been analyzed. The modified nucleoside, 5-[3-(4-azido-2,3,5,6-tetrafluorobenzamid
Autor:
I. O. Petruseva, Olga I. Lavrik, Vladimir N. Silnikov, Lyudmila S. Koroleva, A. N. Evdokimov, Alexandra Y. Tsidulko, Alexander V. Popov, Yury N. Vorobiev, Alexander A. Lomzov
Publikováno v:
DNA Repair. 61:86-98
Mammalian nucleotide excision repair (NER) eliminates the broadest diversity of bulky lesions from DNA with wide specificity. However, the double incision efficiency for structurally different adducts can vary over several orders of magnitude. Theref
Publikováno v:
DNA Repair. 108:103225
Clustered damage of DNA consists of two or more lesions located within one or two turns of the DNA helix. Clusters consisting of lesions of various structures can arise under the influence of strong damaging factors, especially if the cells have a co
Publikováno v:
Acta Naturae. 9:31-41
The naked mole-rat (Heterocephalus glaber) is one of the most promising models used to study genome maintenance systems, including the effective repair of damage to DNA. The naked mole-rat is the longest lived rodent species, which is extraordinarily
Autor:
Sergey S. Bogachev, Olga I. Lavrik, Ekaterina A. Potter, Alexey A. Popov, I. O. Petruseva, A. N. Evdokimov, Anastasia S. Proskurina, E. V. Dolgova, Sergey I. Bayborodin, Yaroslav R. Efremov
Publikováno v:
Nucleic acid therapeutics. 29(5)
Murine Krebs-2 tumor-initiating stem cells are known to natively internalize extracellular double-stranded DNA fragments. Being internalized, these fragments interfere in the repair of chemically induced interstrand cross-links. In the current invest