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Monoclonal antibody directed to a fibrinogen A?? #529???539 epitope inhibits ??-chain crosslinking by transglutaminases

Autor: J H Sobel, G. P. Samokhin, G.F. Kalantarov, T. N. Vlasik, O. V. Mitkevich, J R Shainoff, I. N. Trakht, Z A Streltsova

Publikováno v: Blood Coagulation & Fibrinolysis. 7:85-92

A monoclonal antibody (5A2) recognizing a segment near the C-terminus of the fibrin(ogen) A alpha-chain (A alpha #529-539) was found to inhibit alpha-chain crosslinking catalyzed by coagulation factor XIIIa and by tissue-transglutaminase. The rapid g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26162c9783695e039d3620a07ffbf7db
https://doi.org/10.1097/00001721-199601000-00011

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[The plasmoimmunosorption of low-density lipoproteins in the treatment of patients with hereditary hypercholesterolemia]

Autor: G A, Konovalov, S N, Pokrovskiĭ, I N, Trakht, E, Bokchubaev, E I, Volkova, V V, Kukharchuk

Publikováno v: Terapevticheskii arkhiv. 63(7)

The authors describe the experience gained with the use of apheresis of low density lipoproteins with the aid of the Soviet immunosorption columns with polyclonal and monoclonal antibodies in patients with hereditary hypercholesterolemia resistant to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::991af1a0b7c753a842300ae9b2c295a2
https://pubmed.ncbi.nlm.nih.gov/1788813

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Lung is the target organ for a monoclonal antibody to angiotensin-converting enzyme

Autor: S M, Danilov, V R, Muzykantov, A V, Martynov, E N, Atochina, Sakharov IYu, I N, Trakht, V N, Smirnov

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 64(1)

125I-labeled mouse monoclonal antibody (MoAb) to human angiotensin-converting enzyme (ACE), termed 9B9 and cross-reacting with rat and monkey ACE, when injected into the circulation, accumulates in the lung in up to 10 to 20 greater concentrations th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7fa51d81059477e1ad82f95f9d32fde
https://pubmed.ncbi.nlm.nih.gov/1846655

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Localization of apolipoprotein E in normal and atherosclerotic human aorta

Autor: Vladimir N. Smirnov, Alexander D. Dergunov, Alexander A. Chenchik, Edvard M. Tararak, Clemens Sorg, Vladimir R. Babaev, I. N. Trakht, Elena Yanushevskaya

Publikováno v: Atherosclerosis. 85(2-3)

To elucidate the role of apolipoprotein E (apo E) in atherogenesis, we have investigated the localization of apo E in normal and atherosclerotic aortas as well as in other tissues of 32 post-mortem individuals. Using double immunofluorescence it has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bcaebd946341e7a2fea29fba31b649
https://pubmed.ncbi.nlm.nih.gov/2102087

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[Effect of chylomicron remnants on cholesterol metabolism in cultured rabbit hepatocytes: production of very low density lipoproteins and bile acids]

Autor: D K, Novikov, V A, Kosykh, I N, Trakht, E A, Podrez, V S, Repin

Publikováno v: Biokhimiia (Moscow, Russia). 55(10)

Primary cultures of rabbit hepatocytes were used to investigate the effect of purified (B-100 free) chylomicron remnants (CR) on lipid and bile acid metabolism. ApoB-100-containing lipoproteins were removed from the CR-enriched plasma fraction by aff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2cb4ef8b15e072b1883206dff566545e
https://pubmed.ncbi.nlm.nih.gov/2078630

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[Immunocytochemical analysis of apoprotein E distribution in human tissues]

Autor: V R, Babaev, A D, Dergunov, I N, Trakht, V N, Sirotkin, E M, Tararak, E Iu, Dediueva

Publikováno v: Arkhiv anatomii, gistologii i embriologii. 98(6)

Localization of apoprotein E (apo E) has been studied in different human tissues. For this aim the immunoperoxidase method and peroxidase-antiperoxidase complex, polyclonal and monoclonal antibodies, to apo E have been used. In every human tissue ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4ee10fe62bce7ac387aba1b13c37287
https://pubmed.ncbi.nlm.nih.gov/2400332

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[The localization of apoprotein E in the normal human aortic wall and in atherosclerosis]

Autor: V R, Babaev, A D, Dergunov, L R, Kurashvili, V N, Sirotkin, E V, Ianushevskiĭ, I N, Trakht, E M, Tararak

Publikováno v: Arkhiv patologii. 52(7)

The authors studied the distribution of apoprotein E (apoE) in normal and atherosclerotic human aortic wall. Double immunofluorescent technique and a set of mono- and polyclonal antibodies were used in the study. Apo E was found in normal intima of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67ef83e83a4c31e16bad65b9063b5851
https://pubmed.ncbi.nlm.nih.gov/2285364

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Monoclonal Antibody to Lipid a Prevents the Development of Haemodynamic Disorders in Endotoxemia

Autor: A. Ju. Mayatnikov, D. V. Borovikov, T. N. Vlasik, A. L. Tabachnik, I. N. Trakht, V. L. Golubykh, G. F. Kalantarov, A. A. Shnyra

Publikováno v: Endotoxin ISBN: 9781475751420

It has been recognized that gram-negative bacteriaemia is the major cause of hospital sepsis. The pathology of gram-negative sepsis is attributed to endotoxin. Endotoxins of all gram-negative bacteria have the same lipid moiety, so called lipid A, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a839751d10720a8052060cf6c7770c64
https://doi.org/10.1007/978-1-4757-5140-6_63

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