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Akademický článek
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Publikováno v:
J Oncol Pharm Pract
Purpose A survey of guidelines and current practices was conducted to examine the safe handling procedures for antineoplastic and other hazardous drugs that are used in 24 countries including the Americas, Europe, the Mideast, Far East, and Australia
Publikováno v:
Journal of Chromatography B. 1060:316-324
The medical treatment of cancer with antineoplastic drugs is routine, but careful biomonitoring for these powerful drugs in individual healthcare worker exposure is necessary to ensure that engineering controls and exposure intervention measures are
Autor:
Clayton B'Hymer, Patricia I Mathias
Publikováno v:
Biomarkers. 21:293-315
This review describes recent selected HPLC/MS methods for the determination of urinary mercapturates that are useful as noninvasive biomarkers in characterizing human exposure to electrophilic industrial chemicals in occupational and environmental st
Akademický článek
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Autor:
Roger L. Gibson, Christine A. Toennis, Clayton B’Hymer, Kate L. Marlow, Mary Ann Butler, Patricia I. Mathias, Edward F. Krieg, John C. Clark, Narendra P. Singh
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 747:218-227
The genotoxicity of jet propulsion fuel 8 (JP-8) was assessed in the leukocytes of archived blood specimens from U.S. Air Force personnel using the comet assay. No differences in mean comet assay measurements were found between low, moderate, and hig
Autor:
Patricia I. Mathias, Clayton B’Hymer, Kenneth L. Cheever, Katherine L. Marlow, Kevin W. Hanley, Belinda C. Johnson
Publikováno v:
Toxicology Mechanisms and Methods. 22:526-532
Three metabolites of 1-bromopropane (1-BP) were measured in urine samples collected from 30 workers exposed to 1-BP at two facilities making furniture seat cushions and evaluated for use as biomarkers of exposure. The mercapturic acid metabolite, N-a
Akademický článek
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Autor:
Clayton B'Hymer, Patricia I Mathias
High-performance liquid chromatography/mass spectrometry (HPLC/MS) is sensitive and specific for targeted quantitative analysis and is readily utilized for small molecules from biological matrices. This brief review describes recent selected HPLC/MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668a5fab28f14f233552238cbda975ef
https://europepmc.org/articles/PMC4530631/
https://europepmc.org/articles/PMC4530631/
Publikováno v:
Journal of Medical Microbiology. 49:841-844
The bactericidal activity and mechanisms of action of the new fluoroquinolone gemifloxacin were investigated against the laboratory strains Escherichia coli KL16, Staphylococcus aureus E3T and Streptococcus pneumoniae C3LN4. Gemifloxacin was found to