Zobrazeno 1 - 10
of 24
pro vyhledávání: '"I M Todor"'
Autor:
O. O. Shevchuk, I. M. Todor, N. Yu. Lukianova, N. K. Rodionova, V. G. Nikolaev, V. F. Chekhun
Publikováno v:
International Journal of Medicine and Medical Research, Vol 5, Iss 1, Pp 66-74 (2019)
Background. Side effects of antineoplastic agents (especially leukopenia and neutropenia) could be the main limiting factors for efficient treatment. Objective. The research is aimed at the study of myeloprotective capability of biosimilars of gra
Externí odkaz:
https://doaj.org/article/d4054e6bf3ad4e68b86296616f2aef95
Publikováno v:
International Journal of Medicine and Medical Research, Vol 4, Iss 2, Pp 72-78 (2019)
Background. Bone marrow (BM) that contains hematopoietic cells of various lineages is a sensitive target for a number of cytotoxic agents including chemotherapy drugs. Objective. Flow cytometry (FCM) was chosen to test cytotoxicity in BM of rats,
Externí odkaz:
https://doaj.org/article/3c02507a71a34a0ab2ac408cdcfc4db2
Autor:
V. F. Chekhun, Yu. V. Lozovska, A. P. Burlaka, I. I. Ganusevich, Yu. V. Shvets, N. Yu. Lukyanova, I. M. Todor, N. A. Tregubova, L. A. Naleskina
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 1, Pp 99-108 (2016)
The study was aimed at determining the changes of metal-containing proteins in blood serum and tumor tissue of animals with parental and doxorubicin-resistant strains of Walker-256 carcinosarcoma before and after the cytostatic administration. It has
Externí odkaz:
https://doaj.org/article/acb7f0aab61a41498461a09b7dab5fb7
Autor:
V. F. Chekhun, Yu. V. Lozovska, A. P. Burlaka, I. I. Ganusevich, Yu. V. Shvets, N. Yu. Lukianova, I. M. Todor, D. V. Demash, A. A. Pavlova, L. A. Naleskina
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 2, Pp 103-112 (2015)
The study was focused on the detection of changes in serum and tumor metal-containing proteins in animals during development of doxorubicin-resistant phenotype in malignant cells after 12 courses of chemotherapy. We found that on every stage of resis
Externí odkaz:
https://doaj.org/article/1921361976924d928f68b362b595f6c8
Publikováno v:
Vіsnik Naukovih Doslіdžen', Vol 0, Iss 1 (2017)
Myelosuppression during intensive chemotherapy frequently is a reason of therapy disruption and rising of patients’ lethality. Effective method for prevention and treatment of neutropenia today is granulocyte colony stimulating factor (G-CSF) drugs
Externí odkaz:
https://doaj.org/article/1c2357dabd9f461bb23707c449e2a921
Autor:
N. Yu. Lukianova, I. M. Todor, Vasyl F. Chekhun, V. G. Nikolaev, N. K. Rodionova, O. O. Shevchuk
Publikováno v:
International Journal of Medicine and Medical Research, Vol 5, Iss 1, Pp 66-74 (2019)
Background. Side effects of antineoplastic agents (especially leukopenia and neutropenia) could be the main limiting factors for efficient treatment. Objective. The research is aimed at the study of myeloprotective capability of biosimilars of granul
Publikováno v:
International Journal of Medicine and Medical Research, Vol 4, Iss 2, Pp 72-78 (2019)
Background. Bone marrow (BM) that contains hematopoietic cells of various lineages is a sensitive target for a number of cytotoxic agents including chemotherapy drugs. Objective. Flow cytometry (FCM) was chosen to test cytotoxicity in BM of rats, tha
Publikováno v:
Experimental Oncology. 38:84-88
Aim: To investigate the role of hepcidin (Hepc) in the formation of cells malignant phenotype in vitro and its expression in the dyna mics of growth of Walker-256 carcinosarcoma with different sensitivity to doxorubicin (Dox). Materials and Methods:
Autor:
I V, Zalutskii, N Y, Lukianova, D M, Storchai, A P, Burlaka, Y V, Shvets, T V, Borikun, I M, Todor, V S, Lukashevich, Y A, Rudnichenko, V F, Chekhun
Publikováno v:
Experimental oncology. 39(2)
To investigate the mechanisms of cytotoxic activity and pro-/antioxidant effect of lactoferrin on hormone receptor-positive and receptor-negative breast cancer cells in vitro.The study was performed on receptor-positive (MCF-7, T47D) and receptor-neg
Publikováno v:
Cytology and Genetics. 49:42-48
The article discusses the study of geno- and cytotoxic effects of 5 nm-sized gold nanoparticles (GNPs) administered to mice at the concentrations of 30 and 60 μg/kg of animals’ body weight on the erythroid lineage cells from the bone marrow (BM) a