Zobrazeno 1 - 10
of 131
pro vyhledávání: '"I M, Modlin"'
Autor:
M. Kidd, P.L. Filosso, Karel Pacak, A. Frilling, I. M. Modlin, Anna Malczewska, Lisa Bodei, Christos Toumpanakis, Massimo Falconi, Gerlof D. Valk, Kjell Öberg
Publikováno v:
Ann Oncol
BACKGROUND: Biomarkers are key tools in cancer management. In neuroendocrine tumors (NETs), Chromogranin A (CgA) was considered acceptable as a biomarker. We compared the clinical efficacy of a multigenomic blood biomarker (NETest) to CgA over a 5-ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493b439d1743c0bf1c50f2a1e330902a
https://hdl.handle.net/11380/1294986
https://hdl.handle.net/11380/1294986
Autor:
Dafydd Aled Rees, Marisol Vazquez, Roswitha Pfragner, Borzo Gharibi, Atul Kalhan, I. M. Modlin, Mark Kidd, James Neal, Jack Ham, Bharat Jasani
Publikováno v:
Purinergic Signalling. 8:265-274
The clinical management of neuroendocrine tumours is complex. Such tumours are highly vascular suggesting tumour-related angiogenesis. Adenosine, released during cellular stress, damage and hypoxia, is a major regulator of angiogenesis. Herein, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b6c5c5ac81a4e37ffe33a2337a4248
https://doi.org/10.1007/s11302-011-9280-5
https://doi.org/10.1007/s11302-011-9280-5
Publikováno v:
Regulatory Peptides. 143:109-117
Gastrin regulates ECL cell histamine release and is a critical determinant of acid secretion. ECL cell secretion and proliferation is inhibited by gastrin antagonists and somatostatin but little is known about the role of dopamine agonists in this pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fc1f16966c957544f5b78908be17df
https://doi.org/10.1016/j.regpep.2007.04.002
https://doi.org/10.1016/j.regpep.2007.04.002
Autor:
L, Bodei, M, Kidd, I M, Modlin, V, Prasad, S, Severi, V, Ambrosini, D J, Kwekkeboom, E P, Krenning, R P, Baum, G, Paganelli, I, Drozdov
Publikováno v:
European journal of nuclear medicine and molecular imaging. 42(9)
Precise determination of neuroendocrine tumor (NET) disease status and response to therapy remains a rate-limiting concern for disease management. This reflects limitations in biomarker specificity and resolution capacity of imaging. In order to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c7ea623c20da5ac4e88729e7dbc66a7
https://pubmed.ncbi.nlm.nih.gov/26067089
https://pubmed.ncbi.nlm.nih.gov/26067089
Publikováno v:
The American journal of gastroenterology. 110(8)
Current monoanalyte blood-based biomarkers for the diagnosis and follow-up of neuroendocrine tumors (NETs) do not achieve satisfactory metrics of sensitivity and specificity. We report the sensitivity and selectivity of the PCR-based test, the NETest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e97ad63c65068edd47ae1a2b007c7d8
https://pubmed.ncbi.nlm.nih.gov/26032155
https://pubmed.ncbi.nlm.nih.gov/26032155
Autor:
I. M. Modlin, M. Kidd, Jarosław B. Ćwikła, K. Roszkowska-Purska, Lisa Bodei, Jakub Pałucki, Anna Lewczuk, A. Kolasinska-Cwikla, L. Sawicki
Publikováno v:
Annals of Oncology. 28:v151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e0fb5bf1dff2e49cd3b4c90d021a71
https://doi.org/10.1093/annonc/mdx368.026
https://doi.org/10.1093/annonc/mdx368.026
Publikováno v:
The American Journal of Gastroenterology. 93:306-310
Several areas of broad agreement exist concerning the management of specific patient groups with clear-cut complications of H. pylori-colonization. Other aspects of this infection remain less well defined. These include the mode of transmission and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150d0255c8565a9d93ba69ce08d11a54
https://doi.org/10.1016/s0002-9270(98)00007-0
https://doi.org/10.1016/s0002-9270(98)00007-0
Gastroenteropancreatic (GEP) and bronchopulmonary (BP) neuroendocrine neoplasms (NENs) represent the second most prevalent gastrointestinal malignancy and exhibit a poor prognosis, but their etiopathogenesis is unknown. This article explores the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e11641caca52b7a2b2eac693da4f259
https://doi.org/10.1016/b978-0-12-374984-0.00198-4
https://doi.org/10.1016/b978-0-12-374984-0.00198-4
Autor:
Håkan Ahlman, Ola Nilsson, I M Modlin, Elvar Theodorsson, Bo Wängberg, Lars Kölby, G. Granérus
Publikováno v:
Endocrinology. 137:4435-4442
Histamine is an important stimulator of gastric acid secretion. In experimental animals, inhibition of acid secretion by long term histamine2 receptor blockade causes hypergastrinemia, proliferation of enterochromaffin-like (ECL) cells, and formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a9cc87109a4bd443e4a2c04369858a
https://doi.org/10.1210/endo.137.10.8828505
https://doi.org/10.1210/endo.137.10.8828505