Zobrazeno 1 - 5
of 5
pro vyhledávání: '"I M, Maisonneuve"'
Autor:
Patrick A. Jokiel, Liwen He, Stanley D. Glick, I. M. Maisonneuve, Jean M. Bidlack, C. J. Pace, Martin E. Kuehne, Mark W. Fleck
Publikováno v:
Journal of Medicinal Chemistry. 46:2716-2730
Variation of the methoxycarbonyl and C-18 substituents of the antiaddictive compound 18-methoxycoronaridine, and contraction of its isoquinuclidine ring segment, provided 15 congeners for SAR evaluation at opioid and alpha3beta4 nicotinic acetylcholi
Publikováno v:
British Journal of Pharmacology. 129:1561-1568
Ibogaine and 18-methoxycoronaridine are naturally occurring alkaloids reported to possess antiaddictive properties in several models of drug dependence. We have examined their effect at μ-opioid receptors regulating neurogenic contractions of severa
Publikováno v:
The Alkaloids. Chemistry and biology. 56
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
The purpose of this study was to determine the effects of chronic "binge" administration of cocaine (hourly x 3 i.p.). Male Fisher rats were treated for 13 days with cocaine (3 x 10 or 15 mg/kg) or saline (3 x 1 ml/kg). On day 14, microdialysis was p
Autor:
I M, Maisonneuve, M J, Kreek
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 268(2)
To address a growing concern about the relevance of the pattern of cocaine administration used in animal studies, the aim of the present work was to establish the dopamine (DA) response of an acute cocaine "binge" that attempts to parallel as closely