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pro vyhledávání: '"I M, Lico"'
Publikováno v:
ChemInform. 24
Publikováno v:
Drugs under experimental and clinical research. 16(5)
Very little is known about the structure-activity relationship of quinolone antibacterials at the 2-position. Because of the loss of biological activity with 2-methyl and 2-hydroxyl substitution, modifications at C-2 were generally considered to be u
Publikováno v:
Drugs under experimental and clinical research. 16(9)
Tosufloxacin (5, A-61827 tosylate or T-3262) is currently under product development by both Abbott Laboratories and Toyama Chemical Co. Its registration as antibacterial agent has been approved in Japan. It has been found to be extremely effective in