Zobrazeno 1 - 10 of 10 pro vyhledávání: '"I M, Feavers"'
1
A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial
Autor: L, Marsay, C, Dold, C A, Green, C S, Rollier, G, Norheim, M, Sadarangani, M, Shanyinde, C, Brehony, A J, Thompson, H, Sanders, H, Chan, K, Haworth, J P, Derrick, I M, Feavers, M C, Maiden, A J, Pollard
Publikováno v: The Journal of Infection
Summary Objectives Outer membrane vesicle (OMV) vaccines are used against outbreaks of capsular group B Neisseria meningitidis (MenB) caused by strains expressing particular PorA outer membrane proteins (OMPs). Ferric enterobactin receptor (FetA) is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::391f056a743282167f2c27d1ccc21b4f
https://pubmed.ncbi.nlm.nih.gov/25982025
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2
Meningococcal vaccines and vaccine developments
Autor: I M, Feavers
Publikováno v: Methods in molecular medicine. 66
Despite rapid advances in the diagnosis of bacterial infections and the availability of effective antibiotics, meningococcal disease continues to represent a substantial public health problem for most countries (1-4). Disease usually develops rapidly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fbae3068e736e3508411130cb8e22d22
https://pubmed.ncbi.nlm.nih.gov/21336743
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3
Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries
Autor: P J, Brett, I M, Feavers, B M, Charalambous
Publikováno v: Methods in molecular medicine. 66
Although capsular polysaccharide-based vaccines are effective at reducing the incidence of meningococcal disease caused by serogroups A, C, Y, and W135 (1-3), immunization against serogroup B disease using similar strategies has proven unsuccessful (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::988b6d093b68eefa40546e567b6a43cc
https://pubmed.ncbi.nlm.nih.gov/21336756
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5
Tissue specific expression of avian vitellogenin gene is correlated with DNA hypomethylation and in vivo specific protein-DNA interactions
Autor: I M Feavers, Hans-Peter Saluz, M. Vaccaro, Haimin Liang, S. Reiber, M. Hughes, Iain J. McEwan, Jean-Pierre Jost
Publikováno v: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 326(1235)
The avian vitellogenin gene is expressed only in the liver of egg-laying hens. It can, however, be activated in immature chicks or roosters by oestradiol. Parallel to the onset of transcription, there is a demethylation of specific mCpGs in the promo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638b7f55679681281d191a4ba65c1b2d
https://pubmed.ncbi.nlm.nih.gov/1968660
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6
Genomic sequencing and in vivo footprinting of an expression-specific DNase I-hypersensitive site of avian vitellogenin II promoter reveal a demethylation of a mCpG and a change in specific interactions of proteins with DNA
Autor: Hans-Peter Saluz, I M Feavers, Josef Jiricny, Jean-Pierre Jost
Publikováno v: Proceedings of the National Academy of Sciences. 85:6697-6700
Genomic sequencing was used to study the in vivo methylation pattern of two CpG sites in the promoter region of the avian vitellogenin gene. The CpG at position +10 was fully methylated in DNA isolated from tissues that do not express the gene but wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2826fc71ddfd2274d82cfecee8e4f0a
https://doi.org/10.1073/pnas.85.18.6697
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7
An Estradiol-dependent Protein from Chicken Liver Binds Single-stranded DNA and RNA
Autor: J.-P. Jost, I. M. Feavers, Haimin Liang, Iain J. McEwan
Publikováno v: Journal of Biological Chemistry. 264:9114-9117
We have identified two estradiol-dependent single-stranded DNA binding proteins in the nucleus and cytoplasm of chicken hepatocytes that bind the sequence 5'TCACCTTCGCTATG3' in the first exon of the chicken vitellogenin gene. As judged by chromatogra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5c62c266f7401d895fd993d6e87aeee
https://doi.org/10.1016/s0021-9258(18)60498-3
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8
Interaction of two nonhistone proteins with the estradiol response element of the avian vitellogenin gene modulates the binding of estradiol-receptor complex
Autor: Jean-Pierre Jost, Josef Jiricny, I M Feavers, Hans-Peter Saluz, Bruno Moncharmont
The DNA sequence corresponding to the estradiol response element has been synthesized and tested in vitro for the binding of specific proteins. Gel retardation experiments combined with dimethyl sulfate protection experiments revealed that this regio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcb0505f129ea7c5eecdd4863f86811
https://europepmc.org/articles/PMC299314/
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9
An estradiol-dependent protein from chicken liver binds single-stranded DNA and RNA
Autor: I M, Feavers, I J, McEwan, H, Liang, J P, Jost
Publikováno v: The Journal of biological chemistry. 264(16)
We have identified two estradiol-dependent single-stranded DNA binding proteins in the nucleus and cytoplasm of chicken hepatocytes that bind the sequence 5'TCACCTTCGCTATG3' in the first exon of the chicken vitellogenin gene. As judged by chromatogra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b2f54b36ed15822379c5d3b51379655
https://pubmed.ncbi.nlm.nih.gov/2470751
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