Výsledky vyhledávání

Automatic detection and genetic profiling of disseminated neuroblastoma cells

Autor: G, Méhes, A, Luegmayr, C M, Hattinger, T, Lörch, I M, Ambros, H, Gadner, P F, Ambros

Publikováno v: Medical and pediatric oncology. 36(1)

Rare tumor cells circulating in the hematopoietic system can escape identification. On the other hand, the nature of these cells, positive for an immunologiCal tumor marker, cannot be determined without any genetic information.To overcome these probl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c3f6f19b797f38dfcd89a3301f9eb69
https://pubmed.ncbi.nlm.nih.gov/11464886

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Intratumoural heterogeneity of 1p deletions and MYCN amplification in neuroblastomas

Autor: P F, Ambros, I M, Ambros, R, Kerbl, A, Luegmayr, S, Rumpler, R, Ladenstein, G, Amann, H, Kovar, E, Horcher, B, De Bernardi, J, Michon, H, Gadner

Publikováno v: Medical and pediatric oncology. 36(1)

At least three genetic hallmarks identify aggressive tumour behaviour in neuroblastomas; amplification of the oncogene MYCN; deletion (loss of heterozygosity [LOH]) at the short arm of chromosome 1 (del1p36), seen in approximately 28% of the cases; a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e05561309d21ec755c19bbb41f17394
https://pubmed.ncbi.nlm.nih.gov/11464855

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Prognostic impact of deletions at 1p36 and numerical aberrations in Ewing tumors

Autor: C M, Hattinger, S, Rumpler, S, Strehl, I M, Ambros, A, Zoubek, U, Pötschger, H, Gadner, P F, Ambros

Publikováno v: Genes, chromosomescancer. 24(3)

Ewing's sarcoma, peripheral primitive neuroectodermal tumors, and Askin tumors are referred to as Ewing tumors (ETs), and are characterized by high MIC2 expression and a t(11;22)(q24;q12) or other rearrangements involving 22q12. In addition to these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::44475c2181b919bda927f62ab6178071
https://pubmed.ncbi.nlm.nih.gov/10451705

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The International Neuroblastoma Pathology Classification (the Shimada system)

Autor: H, Shimada, I M, Ambros, L P, Dehner, J, Hata, V V, Joshi, B, Roald, D O, Stram, R B, Gerbing, J N, Lukens, K K, Matthay, R P, Castleberry

Publikováno v: Cancer. 86(2)

The International Neuroblastoma Pathology Committee, which is comprised of six member pathologists, was convened with the objective of proposing a prognostically significant and biologically relevant classification based on morphologic features of ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::34009bad92557f024534d20b4bd6f6c1
https://pubmed.ncbi.nlm.nih.gov/10421273

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Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee

Autor: H, Shimada, I M, Ambros, L P, Dehner, J, Hata, V V, Joshi, B, Roald

Publikováno v: Cancer. 86(2)

As part of the international cooperative effort to develop a complete set of International Neuroblastoma Risk Groups, the International Neuroblastoma Pathology Committee (INPC) initiated activities in 1994 to devise a morphologic classification of ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e2a274adaf8de062db0c4846daf1801
https://pubmed.ncbi.nlm.nih.gov/10421272

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Neuroblastoma screening for children: delay, repeat, or delete?

Autor: R, Kerbl, C E, Urban, I M, Ambros, P F, Ambros

Publikováno v: Medical and pediatric oncology. 31(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72bc21f03be161d510da1c031a0967be
https://pubmed.ncbi.nlm.nih.gov/9680938

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Demonstration of the translocation der(16)t(1;16)(q12;q11.2) in interphase nuclei of Ewing tumors

Autor: C M, Hattinger, S, Rumpler, I M, Ambros, S, Strehl, T, Lion, A, Zoubek, H, Gadner, P F, Ambros

Publikováno v: Genes, chromosomescancer. 17(3)

The der(16)t(1;16) has been detected cytogenetically in a number of malignancies including Ewing tumors (ETs). To enable fast and reliable analysis of der(16) chromosomes, we established an interphase cytogenetic approach. By using two DNA probes hyb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28dd8b273e70698c20696839843f46d3
https://pubmed.ncbi.nlm.nih.gov/8946192

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Connatal localized neuroblastoma. The case to delay treatment

Autor: R, Kerbl, C E, Urban, H, Lackner, G, Höfler, I M, Ambros, M, Ratschek, P F, Ambros

Publikováno v: Cancer. 77(7)

Spontaneous regression is well documented for a subset of widespread neuroblastomas (Stage 4S) and for localized residual tumors after incomplete resection. Possible spontaneous regression of untreated localized neuroblastoma in infants is frequently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a80443a27b4b6f25edaccf36a971a659
https://pubmed.ncbi.nlm.nih.gov/8608521

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Detection of Ip36 deletions in paraffin sections of neuroblastoma tissues

Autor: C, Stock, I M, Ambros, G, Mann, H, Gadner, G, Amann, P F, Ambros

Publikováno v: Genes, chromosomescancer. 6(1)

Nonradioactive in situ hybridization (NISH) on sections of paraffin-embedded neuroblastoma tissue was performed to evaluate numerical and structural aberrations of chromosome 1. Two biotinylated probes specific for the heterochromatic (D1Z1) and subt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e4492ebd82208af88899365ba74ee4c
https://pubmed.ncbi.nlm.nih.gov/7680215

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