Zobrazeno 1 - 7
of 7
pro vyhledávání: '"I K Ashok Sivakumar"'
Autor:
Maria Ximena Sosa, I K Ashok Sivakumar, Samantha Maragh, Vamsi Veeramachaneni, Ramesh Hariharan, Minothi Parulekar, Karin M Fredrikson, Timothy T Harkins, Jeffrey Lin, Andrew B Feldman, Pramila Tata, Georg B Ehret, Aravinda Chakravarti
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 10, p e1002737 (2012)
We describe methods for rapid sequencing of the entire human mitochondrial genome (mtgenome), which involve long-range PCR for specific amplification of the mtgenome, pyrosequencing, quantitative mapping of sequence reads to identify sequence variant
Externí odkaz:
https://doaj.org/article/1bf1abfb3b8d4eb796a4ed4b445b9237
Autor:
Dipika Singh, Hedy L. Kindler, Valsamo Anagnostou, Thomas Purcell, Hossein Borghaei, Julie R. Brahmer, Rachel Karchin, Arkadiusz Z. Dudek, Rafael Santana-Davila, Archana Balan, Z. Sun, Sampriti Thapa, Xiaoshan M. Shao, Victor E. Velculescu, Zineb Belcaid, Drew M. Pardoll, Suresh S. Ramalingam, Noushin Niknafs, Suzanne E. Dahlberg, Peter B. Illei, Patrick M. Forde, Christopher Cherry, James R. White, Kellie N. Smith, Hok Yee Chan, Mara Lanis, I K Ashok Sivakumar
Publikováno v:
Nature Medicine
Mesothelioma is a rare and fatal cancer with limited therapeutic options until the recent approval of combination immune checkpoint blockade. Here we report the results of the phase 2 PrE0505 trial (NCT02899195) of the anti-PD-L1 antibody durvalumab
Autor:
Malcolm V. Brock, Benjamin Levy, Jillian Phallen, Matthew D. Hellmann, Victor E. Velculescu, Doreen N. Palsgrove, I K Ashok Sivakumar, Edward Gabrielson, Qing Kay Li, Christine L. Hann, Lamia Rhymee, Valsamo Anagnostou, Peter B. Illei, Patrick M. Forde, Kristen A. Marrone, Alessandro Leal, Josephine Feliciano, Jarushka Naidoo, Daniel C. Bruhm, Franco Verde, James M. Isbell, James R. White, Carolyn Hruban, Janis M. Taube, Tricia R. Cottrell, Robert B. Scharpf, Vilmos Adleff, Drew M. Pardoll, Julie R. Brahmer, Christos S. Georgiades, Rachel Karchin, Noushin Niknafs, Jennifer L. Sauter, Jamie E. Chaft, Kellie N. Smith, Samuel Rosner
Publikováno v:
Cancer Research. 79:1214-1225
Despite the initial successes of immunotherapy, there is an urgent clinical need for molecular assays that identify patients more likely to respond. Here, we report that ultrasensitive measures of circulating tumor DNA (ctDNA) and T-cell expansion ca
Autor:
Lily Zheng, Benjamin Kaminow, Maria Bonsack, Dylan Hirsch, Xiaoshan M. Shao, I K Ashok Sivakumar, Angelika B. Riemer, Rohit Bhattacharya, Rachel Karchin, Victor E. Velculescu, Justin C. Huang, Valsamo Anagnostou, Kymberleigh A. Pagel, Collin Tokheim, Ashton Omdahl
Publikováno v:
Cancer Immunol Res
Computational prediction of binding between neoantigen peptides and major histocompatibility complex (MHC) proteins is an emerging biomarker for predicting patient response to cancer immunotherapy. Current neoantigen predictors focus onin silicoestim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e8549f879594d08f6f6c1d0ef89a35
https://doi.org/10.1101/752469
https://doi.org/10.1101/752469
Autor:
Edward J. Bouwer, I K Ashok Sivakumar, David Berry, Kathryn M. Onesios-Barry, Jody B. G. Proescher
Publikováno v:
Applied and Environmental Microbiology. 80:2440-2450
Many pharmaceuticals and personal care products (PPCPs) have been shown to be biotransformed in water treatment systems. However, little research exists on the effect of initial PPCP concentration on PPCP biotransformation or on the microbial communi
Autor:
Samantha Maragh, Minothi Parulekar, Aravinda Chakravarti, Karin M. Fredrikson, Maria X. Sosa, Pramila Tata, Vamsi Veeramachaneni, Georg Ehret, I K Ashok Sivakumar, Andrew B. Feldman, Ramesh Hariharan, Jeffrey S. Lin, Timothy T. Harkins
Publikováno v:
PLOS Computational Biology, Vol. 8, No 10 (2012) P. e1002737
PLoS Computational Biology
PLoS Computational Biology, Vol 8, Iss 10, p e1002737 (2012)
PLoS Computational Biology
PLoS Computational Biology, Vol 8, Iss 10, p e1002737 (2012)
We describe methods for rapid sequencing of the entire human mitochondrial genome (mtgenome), which involve long-range PCR for specific amplification of the mtgenome, pyrosequencing, quantitative mapping of sequence reads to identify sequence variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd5ce02d5dcf7b62df4cb2883daa2bd
https://archive-ouverte.unige.ch/unige:32235
https://archive-ouverte.unige.ch/unige:32235