Výsledky vyhledávání - "I J ten Berge"

Activation and increased expression of adhesion molecules on peripheral blood lymphocytes is a mechanism for the immediate lymphocytopenia after administration of OKT3

Autor: S, Buysmann, F J, Bemelman, P T, Schellekens, Y, van Kooyk, C G, Figdor, I J, ten Berge

Publikováno v: Blood. 87:404-411

We investigated the mechanism by which antihuman CD3 monoclonal antibodies of the isotypes IgG2a (eg, OKT3) and IgA (eg, IXA) can induce the rapid disappearance of virtually all circulating T lymphocytes. We hypothesize that upregulation of adhesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd0ff88c3aebe272748ed0e92d54eb5
https://doi.org/10.1182/blood.v87.1.404.bloodjournal871404

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Effects of a 3-month course of rosuvastatin in patients with systemic lupus erythematosus

Autor: Maarten Limper, H. ten Cate, Eelco W. Meesters, J de Ruiter, Hjalmar R. Hansen, E. C. M. van Gorp, M D de Kruif, Ajda T. Rowshani, C. A. Spek, I J ten Berge

Publikováno v: Annals of the rheumatic diseases, 68(10). BMJ Publishing Group
Annals of the Rheumatic Diseases, 68(10). BMJ Publishing Group

Systemic lupus erythematosus (SLE) is associated with a highly increased cardiovascular risk. Statins can reduce this risk, but may possess additional anti-inflammatory effects that are relevant for the treatment of SLE. In a preliminary study, we in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d7017a604f59325a2e19b429ef25c7
https://pure.amc.nl/en/publications/effects-of-a-3month-course-of-rosuvastatin-in-patients-with-systemic-lupus-erythematosus(ce9e4f34-d9c4-4b06-80b2-2e3fd673eb02).html

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Interferon-gamma in healthy subjects: selective modulation of inflammatory mediators

Autor: J, de Metz, C E, Hack, J A, Romijn, M, Levi, T A, Out, I J, ten Berge, H P, Sauerwein

Publikováno v: European journal of clinical investigation. 31(6)

It is suggested that interferon-gamma (IFN-gamma), like other cytokines, is a mediator in the host inflammatory response, which could be of importance in the pathophysiology of sepsis. The role of IFN-gamma in human host inflammatory responses, howev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::acdc8e17ffa440a0e8dd6fd5046839ef
https://pubmed.ncbi.nlm.nih.gov/11422404

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OKT3 and IL-2 treatment for purging of the latent HIV-1 reservoir in vivo results in selective long-lasting CD4+ T cell depletion

Autor: R M, van Praag, J M, Prins, M T, Roos, P T, Schellekens, I J, Ten Berge, S L, Yong, H, Schuitemaker, A J, Eerenberg, S, Jurriaans, F, de Wolf, C H, Fox, J, Goudsmit, F, Miedema, J M, Lange

Publikováno v: Journal of clinical immunology. 21(3)

Activation of resting T cells has been proposed to purge the reservoir of HIV-1-infected resting CD4+ T cells. We therefore treated three HIV-1-infected patients on antiretroviral therapy with OKT3, a CD3 monoclonal antibody, and recombinant human IL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3edc03c6632b4e9678ba88a54851f832
https://pubmed.ncbi.nlm.nih.gov/11403229

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Rejection of a kidney transplant does not always lead to priming of cytotoxic T cells against mismatched donor HLA class I antigens

Autor: C A, van Kampen, M F, Versteeg-van der Voort Maarschalk, D L, Roelen, I J, ten Berge, F H, Claas

Publikováno v: Transplantation. 71(7)

Previous studies showed that graft rejection is often associated with the presence of primed cytotoxic T cells (CTLs) with a high avidity for donor cells. Similar high avidity CTLs have been found in individuals who have formed IgG anti-HLA antibodie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::156e5d33df13d132ecb1ab89a92d61e1
https://pubmed.ncbi.nlm.nih.gov/11349711

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Mechanisms of lymphocyte-mediated cytotoxicity in acute renal allograft rejection

Autor: P C, Wever, J G, Boonstra, J C, Laterveer, C E, Hack, F J, van der Woude, M R, Daha, I J, ten Berge

Publikováno v: Transplantation. 66(2)

Graft-infiltrating T-cell (GIC) lines cultured from biopsies obtained during acute renal allograft rejection exhibit donor-specific cytotoxicity toward proximal tubular epithelial cell (PTEC) lines cultured from corresponding biopsies. This system al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c748e59731f4c6dad598469689d459f
https://pubmed.ncbi.nlm.nih.gov/9701275

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The CD8+ granzyme B+ T-cell subset in peripheral blood from healthy individuals contains activated and apoptosis-prone cells

Autor: P C, Wever, H J, Van Der Vliet, L H, Spaeny, A M, Wolbink, F N, Van Diepen, C J, Froelich, C E, Hack, I J, ten Berge

Publikováno v: Immunology. 93(3)

Granzyme B (GrB) has been implicated in induction of apoptosis in target cells. The presence of GrB in peripheral blood CD8+ T cells from healthy individuals was analysed in immunocytochemical and flow cytometric studies. Furthermore, CD8+ GrB- T cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::859d8bf8a0327c73de3cf535b0403916
https://pubmed.ncbi.nlm.nih.gov/9640249

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Administration of OKT3 as a two-hour infusion attenuates first-dose side effects

Autor: S, Buysmann, C E, Hack, F N, van Diepen, J, Surachno, I J, ten Berge

Publikováno v: Transplantation. 64(11)

Use of the murine CD3 monoclonal antibody OKT3 is limited by first-dose side effects, which are thought to be caused by the release of inflammatory mediators. Because these processes might be influenced by the speed of administration, we compared a 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::09ffb5c81dde5ec897d69548cf80a8ab
https://pubmed.ncbi.nlm.nih.gov/9415571

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Apoptosis of acinar cells in pancreas allograft rejection

Autor: J G, Boonstra, P C, Wever, J C, Laterveer, J A, Bruijn, F J, van der Woude, I J, ten Berge, M R, Daha

Publikováno v: Transplantation. 64(8)

Recently it has been recognized that apoptosis of target cells may occur during liver and kidney allograft rejection and is probably induced by infiltrating cells. Pancreas rejection is also characterized by a cellular infiltrate, however, the occurr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6170f26920e90d47f604dd89cc6b9d0
https://pubmed.ncbi.nlm.nih.gov/9355845

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Influence of HLA-DRB1* incompatibility on the occurrence of rejection episodes and graft survival in serologically HLA-DR-matched renal transplant combinations

Autor: N M, Lardy, A R, van der Horst, I J, ten Berge, S, Surachno, J M, Wilmink, L P, de Waal

Publikováno v: Transplantation. 64(4)

The aim of the present study was to analyze the effect of HLA-DRB1* mismatches on graft function and graft survival in 92 patients who received serologically HLA-DR split antigen-matched cadaveric renal transplants.The polymorphic second exon of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4832ec0a3cacb6049e8fe88eb4665327
https://pubmed.ncbi.nlm.nih.gov/9293875

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