Zobrazeno 1 - 4
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pro vyhledávání: '"I J Uings"'
Autor:
S N Farrow, I J Uings
Publikováno v:
Molecular Pathology. 53:295-299
All cells in a multicellular organism are constantly exposed to a variety of extracellular signals that they need to interpret and translate into an appropriate response to their environment. These signals can be soluble factors generated locally (fo
Autor:
I J, Uings, D, Needham, J, Matthews, M, Haase, R, Austin, D, Angell, K, Leavens, J, Holt, K, Biggadike, S N, Farrow
Publikováno v:
British journal of pharmacology. 169(6)
Glucocorticoids are highly effective therapies for a range of inflammatory diseases. Advances in the understanding of the diverse molecular mechanisms underpinning glucocorticoid action suggest that anti-inflammatory molecules with reduced side effec
Publikováno v:
Biochemical Journal. 281:597-600
The tyrosine kinase inhibitors ST271, ST638 and erbstatin inhibited phospholipase D (PLD) activity in human neutrophils stimulated by fMet-Leu-Phe, platelet-activating factor and leukotriene B4. These compounds did not inhibit phorbol ester-stimulate
Publikováno v:
Biochemical pharmacology. 55(3)
A quantitative assay for measuring the autophosphorylation of platelet-derived growth factor (PDGF) receptors in intact vascular smooth muscle cells has been developed and used to screen for novel tyrosine kinase (TK) inhibitors. Several novel inhibi