Zobrazeno 1 - 10
of 54
pro vyhledávání: '"I J, Goldberg"'
Autor:
V. S. Peche, T. A. Pietka, M. Jacome-Sosa, D. Samovski, H. Palacios, G. Chatterjee-Basu, A. C. Dudley, W. Beatty, G. A. Meyer, I. J. Goldberg, N. A. Abumrad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of caveolin-1 tyrosine-14 (Cav-1Y14) and ceramide generation in cav
Externí odkaz:
https://doaj.org/article/6f251f202667484391582bbdd86d20a1
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 1, Pp 77-85 (1997)
We have shown previously that the activity of lipoprotein lipase (LPL), the major enzyme responsible for hydrolysis of triglyceride contained in circulating lipoproteins, is associated with lipoproteins in postheparin plasma. In other studies, microt
Externí odkaz:
https://doaj.org/article/611bf2262e4e4b62b5f80dba8d488555
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 11, Pp 2439-2449 (1996)
Lipoprotein lipase (LPL), the major enzyme responsible for the hydrolysis of triglycerides, is primarily synthesized by adipocytes and myocytes. In addition to synthesis, degradation of cell surface-associated LPL is thought to be important in regula
Externí odkaz:
https://doaj.org/article/7ac0cef2273f4a13a3643f447c4e6328
Autor:
I J Goldberg
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 4, Pp 693-707 (1996)
Although it has been known for over 50 years that lipoprotein lipase (LPL) hydrolyzes triglyceride in chylomicrons, during the past half decade there has been a reinterest in the physiologic and pathophysiologic actions of this enzyme. In part, this
Externí odkaz:
https://doaj.org/article/0623113dae34459aaa480e805a4cdeca
Autor:
J C Rutledge, I J Goldberg
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 7, Pp 1152-1160 (1994)
A cardinal feature of the atherosclerotic lesion is increased low density lipoprotein (LDL) content of the arterial wall. Such increases in vascular wall LDL could result from either increased flux of circulating LDL across the arterial endothelial b
Externí odkaz:
https://doaj.org/article/90a8088714b240c9a26d37bb3521b2f9
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 10, Pp 1569-1577 (1989)
Measurements of enzymatic activity have demonstrated that lipoprotein lipase (LPL), the principal enzyme responsible for hydrolysis of circulating triglyceride, is present in a number of tissues including brain, kidney, and adrenal gland. To determin
Externí odkaz:
https://doaj.org/article/d49279d782ce4150b14bc497650c1fc3
Publikováno v:
Nephrology Dialysis Transplantation. 11:104-107
A major cause of the morbidity and mortality of patients with end-stage renal disease (ESRD) is related to disorders of large blood vessels, especially coronary heart disease. Atherosclerosis, the most common form of this disease, is known to result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b06532dff0501f9fb055b9c891abe43
https://doi.org/10.1093/ndt/11.supp2.104
https://doi.org/10.1093/ndt/11.supp2.104
Autor:
I. J. Goldberg, John C. Rutledge
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 7, Pp 1152-1160 (1994)
A cardinal feature of the atherosclerotic lesion is increased low density lipoprotein (LDL) content of the arterial wall. Such increases in vascular wall LDL could result from either increased flux of circulating LDL across the arterial endothelial b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36437572d679bb2907c7275f4c932826
http://www.sciencedirect.com/science/article/pii/S0022227520399570
http://www.sciencedirect.com/science/article/pii/S0022227520399570
Publikováno v:
Scopus-Elsevier
Journal of Lipid Research, Vol 34, Iss 10, Pp 1793-1803 (1993)
Journal of Lipid Research, Vol 34, Iss 10, Pp 1793-1803 (1993)
Using artificial triglyceride emulsions, we have demonstrated the presence of non-equilibrating pools of apolipoproteins C-II and C-III in human plasma lipoproteins. As the concentrations of acceptor triglycerides were increased, a greater fraction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886b2953ea52ee77cbf57e227ac25601
https://doi.org/10.1016/s0022-2275(20)35742-4
https://doi.org/10.1016/s0022-2275(20)35742-4
Publikováno v:
Journal of the American Society of Nephrology. 3:1409-1415
Patients undergoing maintenance hemodialysis therapy have increased mortality due to cardiovascular disease. One possible etiologic factor for this increased mortality is the lipid abnormalities associated with chronic renal failure. These include el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdbb3ccd177c94fd6e700adb62b8061
https://doi.org/10.1681/asn.v371409
https://doi.org/10.1681/asn.v371409