Zobrazeno 1 - 10
of 16
pro vyhledávání: '"I J, Clifton"'
Publikováno v:
International Journal of Microbiology, Vol 2011 (2011)
Prior to modern typing methods, cross-infection of P. aeruginosa between people with cystic fibrosis (CF) was felt to be rare. Recently a number of studies have demonstrated the presence of clonal strains of P. aeruginosa infecting people with CF. Th
Externí odkaz:
https://doaj.org/article/8f4b7a75eb054f69a8664e6b93b44147
Publikováno v:
Journal of Applied Crystallography. 28:635-640
The Laue Data Module (LDM) has been defined and implemented in Fortran as the basis for new developments in the processing of Laue X-ray diffraction data. It provides a program-independent way of handling, storing and accessing the parameters require
Publikováno v:
The European respiratory journal. 33(4)
To the Editors: An essential role of the lung cancer multidisciplinary team (MDT) is to provide an accurate and prompt diagnosis enabling resection of malignant disease where appropriate, while minimising the risk of unnecessary surgical intervention
Publikováno v:
Journal of Applied Crystallography. 24:267-277
The efficiency of data collection using the Laue technique varies with the wavelength range, the crystal symmetry, the orientation of the crystal in the X-ray beam, the crystal-to-film distance and the acceptance angle of the detector. By optimizing
Publikováno v:
Journal of Applied Crystallography. 23:169-174
Single-crystal synchrotron-radiation Laue photographs of protein crystals and viruses are densely populated and a considerable amount of spatial overlapping of spots often occurs on the films. An integration procedure which enables the efficient deco
Publikováno v:
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 9(5)
There are conflicting guidelines and variations in clinical practice in the management of bone tuberculosis (TB), including spinal TB. A case who received 6 months of treatment in line with current British Thoracic Society (BTS) guidelines, and subse
Autor:
R C, Wilmouth, K, Edman, R, Neutze, P A, Wright, I J, Clifton, T R, Schneider, C J, Schofield, J, Hajdu
Publikováno v:
Nature structural biology. 8(8)
Studies on the catalytic mechanism and inhibition of serine proteases are widely used as paradigms for teaching enzyme catalysis. Ground-breaking work on the structures of chymotrypsin and subtilisin led to the idea of a conserved catalytic triad for
Publikováno v:
European journal of biochemistry. 268(10)
Human beta-casomorphin-7 (NH2-Tyr-Pro-Phe-Val-Glu-Pro-Ile-CO2H) is a naturally occurring peptide inhibitor of elastase that has been shown to form an acyl-enzyme complex stable enough for X-ray crystallographic analysis at pH 5. To investigate the im
Autor:
H J, Lee, M D, Lloyd, I J, Clifton, K, Harlos, A, Dubus, J E, Baldwin, J M, Frere, C J, Schofield
Publikováno v:
The Journal of biological chemistry. 276(21)
Deacetoxycephalosporin C synthase is an iron(II) 2-oxoglutaratedependent oxygenase that catalyzes the oxidative ring-expansion of penicillin N to deacetoxycephalosporin C. The wild-type enzyme is only able to efficiently utilize 2-oxoglutarate and 2-
Publikováno v:
The Biochemical journal.
beta-Lactams inhibit a range of enzymes via acylation of nucleophilic serine residues. Certain gamma-lactam analogues of monocyclic beta-lactams have also been shown to be reversible inhibitors of porcine pancreatic elastase (PPE), forming acyl-enzym